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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
08/01/1997 |
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Data da última atualização: |
17/05/2023 |
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Autoria: |
ADAM, S. E. I.; TARTOUR, G. |
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Título: |
Effects of Ipomoea carnea on the liver and on serum enzymes in young ruminants. |
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Ano de publicação: |
1973 |
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Fonte/Imprenta: |
Journal of Comparative Pathology, v. 83, n. 4, p. 531-542, Oct. 1973. |
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DOI: |
10.1016/0021-9975(73)90011-x |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: The sequential changes in the livers of 10 goats, 3 sheep and 2 calves given daily oral doses of 5 g./kg. body weight of fresh leaves of Ipomoea carnea were studied by serial biopsy. Seven goats and 2 sheep died during the 5 to 107 day period and 3 other goats and 1 sheep were killed in a moribund state, 121 days after the commencement of dosing. Neither of the 2 calves died during the experiment. Inappetence, dullness, dyspnoea and paresis of the hind limbs were prominent clinical signs of Ipomoea poisoning in both goats and sheep. Gradual deterioration of the general condition and debility were seen in one of the calves. Both calves were killed on the 121st day. Reduction in cytoplasmic basophilia of the liver cells, fatty change, loss of glycogen, focal hepatocellular necrosis, accumulation of mononuclear cells and polymorphs, new bile ductule formation and portal fibrosis developed between the 21 and 121 days in goats and sheep. None of the calves showed hepatic portal fibroplasia. Regression of the parenchymal-cell changes was seen in one of the calves. All animals showed an increase in the concentrations of glutamate-oxaloacetate transaminase and arginase in the serum. Glutamate pyruvate transaminase activity did not change. Post-mortem examination of goats, sheep and one of the calves revealed excess fluid in the serous cavities, oedema of the lungs, congestion of the kidneys, subendocardial haemorrhage and necrosis of the liver and hepatic fibrosis. |
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Palavras-Chave: |
Aspartate Aminotransferases; Bioquimica serica; Pathology Liver; Patologia; Pulmonary Edema. |
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Thesagro: |
Caprino; Intoxicação; Planta Tóxica. |
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Thesaurus Nal: |
Animal pathology; Arginase; Enzymology; Goat diseases; Goats; Hyperplasia; Ipomoea carnea; Kidneys; Plant poisoning; Sheep diseases. |
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Categoria do assunto: |
H Saúde e Patologia |
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Marc: |
LEADER 02501naa a2200361 a 4500
001 1523468
005 2023-05-17
008 1973 bl uuuu u00u1 u #d
024 7 $a10.1016/0021-9975(73)90011-x$2DOI
100 1 $aADAM, S. E. I.
245 $aEffects of Ipomoea carnea on the liver and on serum enzymes in young ruminants.$h[electronic resource]
260 $c1973
520 $aAbstract: The sequential changes in the livers of 10 goats, 3 sheep and 2 calves given daily oral doses of 5 g./kg. body weight of fresh leaves of Ipomoea carnea were studied by serial biopsy. Seven goats and 2 sheep died during the 5 to 107 day period and 3 other goats and 1 sheep were killed in a moribund state, 121 days after the commencement of dosing. Neither of the 2 calves died during the experiment. Inappetence, dullness, dyspnoea and paresis of the hind limbs were prominent clinical signs of Ipomoea poisoning in both goats and sheep. Gradual deterioration of the general condition and debility were seen in one of the calves. Both calves were killed on the 121st day. Reduction in cytoplasmic basophilia of the liver cells, fatty change, loss of glycogen, focal hepatocellular necrosis, accumulation of mononuclear cells and polymorphs, new bile ductule formation and portal fibrosis developed between the 21 and 121 days in goats and sheep. None of the calves showed hepatic portal fibroplasia. Regression of the parenchymal-cell changes was seen in one of the calves. All animals showed an increase in the concentrations of glutamate-oxaloacetate transaminase and arginase in the serum. Glutamate pyruvate transaminase activity did not change. Post-mortem examination of goats, sheep and one of the calves revealed excess fluid in the serous cavities, oedema of the lungs, congestion of the kidneys, subendocardial haemorrhage and necrosis of the liver and hepatic fibrosis.
650 $aAnimal pathology
650 $aArginase
650 $aEnzymology
650 $aGoat diseases
650 $aGoats
650 $aHyperplasia
650 $aIpomoea carnea
650 $aKidneys
650 $aPlant poisoning
650 $aSheep diseases
650 $aCaprino
650 $aIntoxicação
650 $aPlanta Tóxica
653 $aAspartate Aminotransferases
653 $aBioquimica serica
653 $aPathology Liver
653 $aPatologia
653 $aPulmonary Edema
700 1 $aTARTOUR, G.
773 $tJournal of Comparative Pathology$gv. 83, n. 4, p. 531-542, Oct. 1973.
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| 1. |  | GUIMARÃES, C. R. B.; SEBER, M. F.; NASCIMENTO NETO, J. da P.; FERNANDES, C. A. C.; RODRIGUES, E. P. C. D.; TORRES, B. A. P.; VIANA, J. H. M.; PALHÃO, M. P. Uterine tone: a neglected criterion for the selection of bovine embryo transfer recipients. Reproduction in Domestic Animals, v. 59, n. 7, e14671, 2024.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 3 |
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