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 | Acesso ao texto completo restrito à biblioteca da Embrapa Caprinos e Ovinos. Para informações adicionais entre em contato com cnpc.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
01/08/1992 |
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Data da última atualização: |
06/06/2023 |
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Autoria: |
CORK, L. C.; HADLOW, W. J.; GORHAM, J. R.; PIPER, R. C.; CRAWFORD, T. B. |
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Título: |
Pathology of viral leukoencephalomyelitis of goats. |
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Ano de publicação: |
1974 |
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Fonte/Imprenta: |
Acta Neuropathologica, v. 29, n. 4, p. 281-292, 1974. |
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DOI: |
10.1007/BF00685482. |
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Idioma: |
Inglês |
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Conteúdo: |
The morphologic changes of viral leukoencephalomyelitis of goats (VLG), an afebrile paralytic disease of 2--4 month old kids, were studied in 13 naturally infected goats: 11 during the first 5--22 days of clinical disease and two that survived 8 months and 3 years after onset of clinical signs. Lesions in the early clinical phase of the disease included interstitial pneumonia and widely disseminated myelinoclastic perivascular lesions in the brain and spinal cord. In the central nervous system, hypertrophied and hyperplastic reticulin fibers of the vascular sheath encompassed an inflammatory cell infiltrate composed of lymphocytes, plasma cells, and macrophages. Occasionally, malacia occurred, and several animals had transverse myelitis. Neuronal necrosis and neuronophagia were not features of the disease. Lesions were most frequent in the subpia and subependyma. Pulmonary lesions were not present in goats that survived the initial clinical phase of the disease, but myelin had disappeared from large areas of the spinal cord and from small loci in the brain. Nodular accumulations of mononuclear cells and small perivascular cuffs were also present in the central nervous system. VLG resembles visna in the topographic distribution and myelinoclastic nature of its lesions. Like visna, it bears some resemblance to post-infectious encephalitis of man. |
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Palavras-Chave: |
Demyelinating diseases; Doenca infecciosa; Encephalomyelitis; Virus diseases. |
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Thesagro: |
Caprino; Doença; Encefalite; Sistema Nervoso. |
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Thesaurus Nal: |
Animal disease models; Animal pathology; Brain; Disease transmission; Goat diseases; Goats; Lymphocytes; Plasma cells; Spinal cord. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02389naa a2200385 a 4500
001 1522847
005 2023-06-06
008 1974 bl uuuu u00u1 u #d
024 7 $a10.1007/BF00685482.$2DOI
100 1 $aCORK, L. C.
245 $aPathology of viral leukoencephalomyelitis of goats.$h[electronic resource]
260 $c1974
520 $aThe morphologic changes of viral leukoencephalomyelitis of goats (VLG), an afebrile paralytic disease of 2--4 month old kids, were studied in 13 naturally infected goats: 11 during the first 5--22 days of clinical disease and two that survived 8 months and 3 years after onset of clinical signs. Lesions in the early clinical phase of the disease included interstitial pneumonia and widely disseminated myelinoclastic perivascular lesions in the brain and spinal cord. In the central nervous system, hypertrophied and hyperplastic reticulin fibers of the vascular sheath encompassed an inflammatory cell infiltrate composed of lymphocytes, plasma cells, and macrophages. Occasionally, malacia occurred, and several animals had transverse myelitis. Neuronal necrosis and neuronophagia were not features of the disease. Lesions were most frequent in the subpia and subependyma. Pulmonary lesions were not present in goats that survived the initial clinical phase of the disease, but myelin had disappeared from large areas of the spinal cord and from small loci in the brain. Nodular accumulations of mononuclear cells and small perivascular cuffs were also present in the central nervous system. VLG resembles visna in the topographic distribution and myelinoclastic nature of its lesions. Like visna, it bears some resemblance to post-infectious encephalitis of man.
650 $aAnimal disease models
650 $aAnimal pathology
650 $aBrain
650 $aDisease transmission
650 $aGoat diseases
650 $aGoats
650 $aLymphocytes
650 $aPlasma cells
650 $aSpinal cord
650 $aCaprino
650 $aDoença
650 $aEncefalite
650 $aSistema Nervoso
653 $aDemyelinating diseases
653 $aDoenca infecciosa
653 $aEncephalomyelitis
653 $aVirus diseases
700 1 $aHADLOW, W. J.
700 1 $aGORHAM, J. R.
700 1 $aPIPER, R. C.
700 1 $aCRAWFORD, T. B.
773 $tActa Neuropathologica$gv. 29, n. 4, p. 281-292, 1974.
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