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 | Acesso ao texto completo restrito à biblioteca da Embrapa Caprinos e Ovinos. Para informações adicionais entre em contato com cnpc.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
01/08/1992 |
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Data da última atualização: |
24/05/2023 |
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Autoria: |
JUN, M. H.; JOHNSON, R. H.; MAGUIRE, D. J.; HOPKINS, P. S. |
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Título: |
Enhancement and metastasis after immunotherapy of ovine squamous-cell carcinoma. |
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Ano de publicação: |
1978 |
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Fonte/Imprenta: |
British Journal of Cancer, v. 38, n. 3, p. 382-391, Sep. 1978. |
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DOI: |
10.1038/bjc.1978.218 |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: Extracts of ovine squamous-cell carcinoma (OSCC) prepared by different procedures, were injected at varying concentrations into 184 tumour-bearing sheep. At a total protein of 0.5 mg and greater, there was significant enhancement and metastasis in all 120 sheep examined. Extracts of OSCC containing less than 0.5 mg protein, or of human squamous-cell carcinoma and normal sheep skin containing high levels of protein, had no effect on subsequent tumour development. Extracts of foetal sheep skin at the 3mg-protein level produced significant enhancement and metastasis. The degree of enhancement was inversely proportional to the developmental stage of the tumour at the time of treatment. |
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Palavras-Chave: |
Patologia. |
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Thesagro: |
Ovino. |
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Thesaurus Nal: |
Immunology; Immunotherapy; Neoplasm antigens; Neoplasm proteins; Sheep diseases; Skin neoplasms; Squamous cell carcinoma. |
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Categoria do assunto: |
H Saúde e Patologia |
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Marc: |
LEADER 01496naa a2200277 a 4500
001 1521311
005 2023-05-24
008 1978 bl uuuu u00u1 u #d
024 7 $a10.1038/bjc.1978.218$2DOI
100 1 $aJUN, M. H.
245 $aEnhancement and metastasis after immunotherapy of ovine squamous-cell carcinoma.$h[electronic resource]
260 $c1978
520 $aAbstract: Extracts of ovine squamous-cell carcinoma (OSCC) prepared by different procedures, were injected at varying concentrations into 184 tumour-bearing sheep. At a total protein of 0.5 mg and greater, there was significant enhancement and metastasis in all 120 sheep examined. Extracts of OSCC containing less than 0.5 mg protein, or of human squamous-cell carcinoma and normal sheep skin containing high levels of protein, had no effect on subsequent tumour development. Extracts of foetal sheep skin at the 3mg-protein level produced significant enhancement and metastasis. The degree of enhancement was inversely proportional to the developmental stage of the tumour at the time of treatment.
650 $aImmunology
650 $aImmunotherapy
650 $aNeoplasm antigens
650 $aNeoplasm proteins
650 $aSheep diseases
650 $aSkin neoplasms
650 $aSquamous cell carcinoma
650 $aOvino
653 $aPatologia
700 1 $aJOHNSON, R. H.
700 1 $aMAGUIRE, D. J.
700 1 $aHOPKINS, P. S.
773 $tBritish Journal of Cancer$gv. 38, n. 3, p. 382-391, Sep. 1978.
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Embrapa Caprinos e Ovinos (CNPC) |
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| 1. |  | GONÇALVES, G. S.; CEMBRANELLI, M. de A. R.; PAIVA, L. DE C.; SILVA, M. V. G. B.; MARTINS, M. F.; PANETTO, J. C. do C.; FERREIRA JÚNIOR, E.; MACHADO, M. A.; REIS, D. R. de L. (ed.). Programa de melhoramento genético da raça Girolando - 7ª Prova de Pré-Seleção de Touros - Maio/2019. Juiz de Fora: Embrapa Gado de Leite, 2019. 25 p. (Embrapa Gado de Leite. Documentos, 238).| Biblioteca(s): Embrapa Gado de Leite. |
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