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Registro Completo |
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Biblioteca(s): |
Embrapa Agroindústria Tropical. |
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Data corrente: |
16/06/2025 |
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Data da última atualização: |
18/06/2025 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
XAVIER FILHO, R. R. B.; RIBEIRO, P. R. V.; SILVA, L. M. A. e; PEREIRA, L. L.; FREIRE, G. A.; MARTINS, C. B. R.; WONG, D. V. T.; DIONISIO, A. P.; ALENCAR, N. M. N. DE; FREDERICO, M. J. S.; CANUTO, K. M. |
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Afiliação: |
RAIMUNDO RIGOBERTO BARBOSA XAVIER FILHO, UNIVERSIDADE ESTADUAL DO CEARÁ; PAULO RICELI VASCONCELOS RIBEIRO, CNPAT; LORENA MARA ALEXANDRE E SILVA, CNPAT; LANDERSON LOPES PEREIRA, UNIVERSIDADE FEDERAL DO CEARÁ; GABRIELA ARAÚJO FREIRE, UNIVERSIDADE FEDERAL DO CEARÁ; CAIO BRUNO RODRIGUES MARTINS, UNIVERSIDADE FEDERAL DO CEARÁ; DEYSI VIVIANA TENAZOA WONG, UNIVERSIDADE FEDERAL DO CEARÁ; ANA PAULA DIONISIO, CNPAT; NYLANE MARIA NUNES DE ALENCAR, UNIVERSIDADE FEDERAL DO CEARÁ; MARISA JADNA SILVA FREDERICO, UNIVERSIDADE FEDERAL DO CEARÁ; KIRLEY MARQUES CANUTO, CNPAT. |
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Título: |
Chemical Composition and Antidiabetic Potential of a Phenolic-Rich Extract from Cashew Fiber. |
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Ano de publicação: |
2025 |
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Fonte/Imprenta: |
ACS Food Science & Technology, 2025. |
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DOI: |
https://doi.org/10.1021/acsfoodscitech.5c00074 |
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Idioma: |
Inglês |
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Conteúdo: |
Cashew fiber is a byproduct used as an ingredient in food products; however, little is known about its functional properties. Therefore, we evaluated the chemical composition and antidiabetic potential of a phenolic-rich extract from the cashew fiber (PECF) using spectrometric techniques and experiments with C57BL/6 mice to assess its effect on glycemia and insulin resistance. In the glucose tolerance test, fasted animals received PECF (1−100 mg/kg i.p.) followed by a glucose load of 2 g/kg. Dexamethasone was used to induce insulin resistance, and the animals received PECF daily for 5 days. As a result, PECF (1 mg/kg) reduced blood glucose, triglycerides, and total cholesterol levels; meanwhile, HDL levels and insulin sensitivity were increased. Its mechanism of action seems to be related to α-glucosidase inhibitory and antioxidant activities of phenolic acids and flavonol glycosides by increasing glutathione and reducing TBARs. Thus, cashew fiber was shown to be a good source of hypoglycemic compounds for plant-based foods and nutraceuticals potentially useful for diabetes control. |
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Palavras-Chave: |
Anacardic acid; Hipoglicemico. |
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Thesagro: |
Anacardium Occidentale; Caju; Diabete. |
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Thesaurus Nal: |
Cashew fruit; Diabetes; Hypoglycemic agents; Polyphenols. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02147naa a2200361 a 4500
001 2176622
005 2025-06-18
008 2025 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1021/acsfoodscitech.5c00074$2DOI
100 1 $aXAVIER FILHO, R. R. B.
245 $aChemical Composition and Antidiabetic Potential of a Phenolic-Rich Extract from Cashew Fiber.$h[electronic resource]
260 $c2025
520 $aCashew fiber is a byproduct used as an ingredient in food products; however, little is known about its functional properties. Therefore, we evaluated the chemical composition and antidiabetic potential of a phenolic-rich extract from the cashew fiber (PECF) using spectrometric techniques and experiments with C57BL/6 mice to assess its effect on glycemia and insulin resistance. In the glucose tolerance test, fasted animals received PECF (1−100 mg/kg i.p.) followed by a glucose load of 2 g/kg. Dexamethasone was used to induce insulin resistance, and the animals received PECF daily for 5 days. As a result, PECF (1 mg/kg) reduced blood glucose, triglycerides, and total cholesterol levels; meanwhile, HDL levels and insulin sensitivity were increased. Its mechanism of action seems to be related to α-glucosidase inhibitory and antioxidant activities of phenolic acids and flavonol glycosides by increasing glutathione and reducing TBARs. Thus, cashew fiber was shown to be a good source of hypoglycemic compounds for plant-based foods and nutraceuticals potentially useful for diabetes control.
650 $aCashew fruit
650 $aDiabetes
650 $aHypoglycemic agents
650 $aPolyphenols
650 $aAnacardium Occidentale
650 $aCaju
650 $aDiabete
653 $aAnacardic acid
653 $aHipoglicemico
700 1 $aRIBEIRO, P. R. V.
700 1 $aSILVA, L. M. A. e
700 1 $aPEREIRA, L. L.
700 1 $aFREIRE, G. A.
700 1 $aMARTINS, C. B. R.
700 1 $aWONG, D. V. T.
700 1 $aDIONISIO, A. P.
700 1 $aALENCAR, N. M. N. DE
700 1 $aFREDERICO, M. J. S.
700 1 $aCANUTO, K. M.
773 $tACS Food Science & Technology, 2025.
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Registro original: |
Embrapa Agroindústria Tropical (CNPAT) |
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