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 | Acesso ao texto completo restrito à biblioteca da Embrapa Gado de Leite. Para informações adicionais entre em contato com cnpgl.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Gado de Leite. |
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Data corrente: |
12/11/2024 |
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Data da última atualização: |
12/11/2024 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
CERQUEIRA, A. F. L. W.; BRANDAO, H. de M.; TAVARES, G. D.; RODARTE, M. P. |
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Afiliação: |
ANA FLÁVIA LAWALL WERNECK CERQUEIRA, UNIVERSIDADE FEDERAL DE JUIZ DE FORA; HUMBERTO DE MELLO BRANDAO, CNPGL; GUILHERME DINIZ TAVARES, UNIVERSIDADE FEDERAL DE JUIZ DE FORA; MIRIAN PEREIRA RODARTE, UNIVERSIDADE FEDERAL DE JUIZ DE FORA. |
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Título: |
Ferulic acid: a review of mechanisms of action, absorption, toxicology, application on wound healing. |
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Ano de publicação: |
2024 |
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Fonte/Imprenta: |
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, v. 23, p. 1-10, 2024. |
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DOI: |
https://doi.org/10.2174/0118715230309592240723105514 |
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Idioma: |
Inglês |
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Conteúdo: |
Ferulic acid is a widely distributed phenolic substance with diverse bioactive properties, which has been widely used in the pharmaceutical, food, and cosmetic industries. Wounds are complex skin lesions to treat and their treatment is long and costly. This encourages the search for alternative treatments, especially in the area of bioactive substances of natural origin. Aims: This work aims to make a bibliographic survey on studies of the use of ferulic acid in the treatment of wounds. Results: The studies found show that ferulic acid acts through different mechanisms of action such as antioxidant, anti-inflammatory, antimicrobial, collagen production, angiogenic, and reepithelialization effects. These properties act synergistically in different stages of healing, which differentiates it from conventional treatments. In addition, ferulic acid has dermal absorption, low skin metabolism, and low toxicity. Conclusion: Studies in this area are recent and further research is needed to expand the possibilities and therapeutic efficiency of ferulic acid in wound healing. |
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Palavras-Chave: |
Ácido ferúlico; Antimicrobiano; Fenólico; Ferida. |
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Thesagro: |
Antiinflamatório; Antioxidante. |
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Categoria do assunto: |
H Saúde e Patologia |
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Marc: |
LEADER 01869naa a2200241 a 4500
001 2169079
005 2024-11-12
008 2024 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.2174/0118715230309592240723105514$2DOI
100 1 $aCERQUEIRA, A. F. L. W.
245 $aFerulic acid$ba review of mechanisms of action, absorption, toxicology, application on wound healing.$h[electronic resource]
260 $c2024
520 $aFerulic acid is a widely distributed phenolic substance with diverse bioactive properties, which has been widely used in the pharmaceutical, food, and cosmetic industries. Wounds are complex skin lesions to treat and their treatment is long and costly. This encourages the search for alternative treatments, especially in the area of bioactive substances of natural origin. Aims: This work aims to make a bibliographic survey on studies of the use of ferulic acid in the treatment of wounds. Results: The studies found show that ferulic acid acts through different mechanisms of action such as antioxidant, anti-inflammatory, antimicrobial, collagen production, angiogenic, and reepithelialization effects. These properties act synergistically in different stages of healing, which differentiates it from conventional treatments. In addition, ferulic acid has dermal absorption, low skin metabolism, and low toxicity. Conclusion: Studies in this area are recent and further research is needed to expand the possibilities and therapeutic efficiency of ferulic acid in wound healing.
650 $aAntiinflamatório
650 $aAntioxidante
653 $aÁcido ferúlico
653 $aAntimicrobiano
653 $aFenólico
653 $aFerida
700 1 $aBRANDAO, H. de M.
700 1 $aTAVARES, G. D.
700 1 $aRODARTE, M. P.
773 $tAnti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry$gv. 23, p. 1-10, 2024.
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