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 | Acesso ao texto completo restrito à biblioteca da Embrapa Gado de Leite. Para informações adicionais entre em contato com cnpgl.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Gado de Leite. |
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Data corrente: |
21/04/2024 |
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Data da última atualização: |
23/04/2024 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
ONORATO, G. de C.; AMARAL, D. L. A. S. do; OLIVEIRA, L. F. C. de; BRANDAO, H. de M.; MUNK, M. |
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Afiliação: |
GEOVANA DE CARVALHO ONORATO, UNIVERSIDADE FEDERAL DE JUIZ DE FORA; DANIELLE LUCIANA AURORA SOARES DO AMARAL, UNIVERSIDADE FEDERAL DE JUIZ DE FORA; LUIZ FERNANDO CAPPA DE OLIVEIRA, UNIVERSIDADE FEDERAL DE JUIZ DE FORA; HUMBERTO DE MELLO BRANDAO, CNPGL; MICHELE MUNK, UNIVERSIDADE FEDERAL DE JUIZ DE FORA. |
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Título: |
Barium titanate nanoparticles exhibit cytocompatibility in cultured bovine fibroblasts: a model for dermal exposure. |
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Ano de publicação: |
2024 |
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Fonte/Imprenta: |
Current Journal of Applied Science and Technology, v. 43, n. 5, article CJAST.115461, 2024. |
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DOI: |
https://doi.org/10.9734/cjast/2024/v43i54372 |
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Idioma: |
Inglês |
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Conteúdo: |
The emergence of barium titanate nanoparticles (BaTiO3 NPs) represents an advancement in various fields such as technology, health, and agribusiness. However, increased production heightens the risk of their dispersion into the environment, thereby raising concerns about potential exposure to animals and humans, including the risk of dermal exposure. This study explores the chemical-physical properties of BaTiO3 NPs and their cytocompatibility using a bovine fibroblast cell model. The size and Zeta potential of the NPs were analyzed using scanning electron microscopy and dynamic light scattering technique. Raman spectroscopy was used to characterize the composition of the BaTiO3 NPs. Bovine fibroblasts were exposed in vitro to NPs (0.1 to 100 μg mL-1 ) for 24 hours to evaluate the cytocompatibility using the Thiazolyl Blue Tetrazolium Bromide assay and Trypan Blue exclusion test. The data were evaluated by analysis of variance and the means compared by the Tukey test. Scanning electron microscopy revealed that BaTiO3 NPs measured approximately 100 nm. Dynamic light scattering analysis indicated a hydrodynamic size of 149.27 nm with a polydispersion index of 0.37, and the Zeta potential was -13mV. Raman spectroscopy analysis highlighted the cubic phase of BaTiO3 NPs. Cytotoxicity tests demonstrated that BaTiO3 NPs did not affect cell viability, with 10 μg mL-1 resulting in enhanced cell proliferation. Overall, these findings underscore the non-toxic characteristics of BaTiO3 NPs in fibroblast cells, positioning them as promising and cytocompatible nanomaterials. MenosThe emergence of barium titanate nanoparticles (BaTiO3 NPs) represents an advancement in various fields such as technology, health, and agribusiness. However, increased production heightens the risk of their dispersion into the environment, thereby raising concerns about potential exposure to animals and humans, including the risk of dermal exposure. This study explores the chemical-physical properties of BaTiO3 NPs and their cytocompatibility using a bovine fibroblast cell model. The size and Zeta potential of the NPs were analyzed using scanning electron microscopy and dynamic light scattering technique. Raman spectroscopy was used to characterize the composition of the BaTiO3 NPs. Bovine fibroblasts were exposed in vitro to NPs (0.1 to 100 μg mL-1 ) for 24 hours to evaluate the cytocompatibility using the Thiazolyl Blue Tetrazolium Bromide assay and Trypan Blue exclusion test. The data were evaluated by analysis of variance and the means compared by the Tukey test. Scanning electron microscopy revealed that BaTiO3 NPs measured approximately 100 nm. Dynamic light scattering analysis indicated a hydrodynamic size of 149.27 nm with a polydispersion index of 0.37, and the Zeta potential was -13mV. Raman spectroscopy analysis highlighted the cubic phase of BaTiO3 NPs. Cytotoxicity tests demonstrated that BaTiO3 NPs did not affect cell viability, with 10 μg mL-1 resulting in enhanced cell proliferation. Overall, these findings underscore the non-toxic characteristics of BaTiO3 ... Mostrar Tudo |
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Palavras-Chave: |
Fibroblasto bovino; Modelos in vitro; Nanomaterial; Nanomaterial cerâmico; Piezoeletricidade; Titanato. |
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Thesagro: |
Bário. |
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Categoria do assunto: |
W Química e Física |
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Marc: |
LEADER 02467naa a2200265 a 4500
001 2163766
005 2024-04-23
008 2024 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.9734/cjast/2024/v43i54372$2DOI
100 1 $aONORATO, G. de C.
245 $aBarium titanate nanoparticles exhibit cytocompatibility in cultured bovine fibroblasts$ba model for dermal exposure.$h[electronic resource]
260 $c2024
520 $aThe emergence of barium titanate nanoparticles (BaTiO3 NPs) represents an advancement in various fields such as technology, health, and agribusiness. However, increased production heightens the risk of their dispersion into the environment, thereby raising concerns about potential exposure to animals and humans, including the risk of dermal exposure. This study explores the chemical-physical properties of BaTiO3 NPs and their cytocompatibility using a bovine fibroblast cell model. The size and Zeta potential of the NPs were analyzed using scanning electron microscopy and dynamic light scattering technique. Raman spectroscopy was used to characterize the composition of the BaTiO3 NPs. Bovine fibroblasts were exposed in vitro to NPs (0.1 to 100 μg mL-1 ) for 24 hours to evaluate the cytocompatibility using the Thiazolyl Blue Tetrazolium Bromide assay and Trypan Blue exclusion test. The data were evaluated by analysis of variance and the means compared by the Tukey test. Scanning electron microscopy revealed that BaTiO3 NPs measured approximately 100 nm. Dynamic light scattering analysis indicated a hydrodynamic size of 149.27 nm with a polydispersion index of 0.37, and the Zeta potential was -13mV. Raman spectroscopy analysis highlighted the cubic phase of BaTiO3 NPs. Cytotoxicity tests demonstrated that BaTiO3 NPs did not affect cell viability, with 10 μg mL-1 resulting in enhanced cell proliferation. Overall, these findings underscore the non-toxic characteristics of BaTiO3 NPs in fibroblast cells, positioning them as promising and cytocompatible nanomaterials.
650 $aBário
653 $aFibroblasto bovino
653 $aModelos in vitro
653 $aNanomaterial
653 $aNanomaterial cerâmico
653 $aPiezoeletricidade
653 $aTitanato
700 1 $aAMARAL, D. L. A. S. do
700 1 $aOLIVEIRA, L. F. C. de
700 1 $aBRANDAO, H. de M.
700 1 $aMUNK, M.
773 $tCurrent Journal of Applied Science and Technology$gv. 43, n. 5, article CJAST.115461, 2024.
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Embrapa Gado de Leite (CNPGL) |
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| Registros recuperados : 22 | |
| 2. |  | MOSCARDI, F.; SOLDORIO, I. L.; PARO, F. E. Estabilidade dos fungos entomopatogênicos Beauveria bassiana e Metarhizium anisopliae em diferentes condições de armazenamento. In: CONGRESSO BRASILEIRO DE ENTOMOLOGIA, 13.; SIMPÓSIO INTERNACIONAL SOBRE "BICUDO" DO ALGODOEIRO, 1.; ENCONTRO SOBRE "COCHONILHA" DA PALMA FORRAGEIRA, 2.; ENCONTRO SOBRE MOSCAS-DAS-FRUTAS, 3., 1991, Recife. Resumos... Recife: SEB, 1991. v. 1. p. 242.| Biblioteca(s): Embrapa Soja. |
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| 3. | | SOSA-GÓMEZ, D. R.; MOSCARDI, F.; SOLDORIO, I. L. Flutuação estacional do inóculo de fungos entomopatogênicos em solos do Paraná sob condições de semeadura direta e convencional de soja. In: CONGRESSO BRASILEIRO DE ENTOMOLOGIA, 13.; SIMPÓSIO INTERNACIONAL SOBRE "BICUDO" DO ALGODOEIRO, 1.; ENCONTRO SOBRE "COCHONILHA" DA PALMA FORRAGEIRA, 2.; ENCONTRO SOBRE MOSCAS-DAS-FRUTAS, 3., 1991, Recife. Resumos... Recife: SEB, 1991. v. 1. p. 247.| Biblioteca(s): Embrapa Soja. |
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| 6. | | MOSCARDI, F.; SOSA-GÓMEZ, D. R.; SOLDORIO, I. L.; PARO, F. E. Avaliação de formulações de Baculovirus anticarsia, destinadas ao controle da lagarta da soja, Anticarsia gemmatalis. In: CONGRESSO BRASILEIRO DE ENTOMOLOGIA, 13.; SIMPÓSIO INTERNACIONAL SOBRE "BICUDO" DO ALGODOEIRO, 1.; ENCONTRO SOBRE "COCHONILHA" DA PALMA FORRAGEIRA, 2.; ENCONTRO SOBRE MOSCAS-DAS-FRUTAS, 3., 1991, Recife. Resumos... Recife: SEB, 1991. v. 1. p. 233.| Biblioteca(s): Embrapa Soja. |
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| 8. | | MORALES C. L. MOSCARDI, F.; KASTELIC, J. C.; PARO, F. E.; SOLDORIO, I. L. Comparação da suscetibilidade de dois noctuideos pragas da soja, Anticarsia gemmatalis Hubner e Pseudoplusia includens (Walker), a Bacillus thuringiensis. In: CONGRESSO BRASILEIRO DE ENTOMOLOGIA, 13.; SIMPÓSIO INTERNACIONAL SOBRE "BICUDO" DO ALGODOEIRO, 1.; ENCONTRO SOBRE "COCHONILHA" DA PALMA FORRAGEIRA, 2.; ENCONTRO SOBRE MOSCAS-DAS-FRUTAS, 3., 1991, Recife. Resumos... Recife: SEB, 1991. v. 1. p. 226.| Biblioteca(s): Embrapa Soja. |
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| 9. | | MORALES C. L.; MSOCARDI, F.; KASTELIC, J. G.; PARO, F. E.; SOLDORIO, I. L. Avaliação de duas metodologias para condução de bioensaios com Baculovirus. In: CONGRESSO BRASILEIRO DE ENTOMOLOGIA, 13.; SIMPÓSIO INTERNACIONAL SOBRE "BICUDO" DO ALGODOEIRO, 1.; ENCONTRO SOBRE "COCHONILHA" DA PALMA FORRAGEIRA, 2.; ENCONTRO SOBRE MOSCAS-DAS-FRUTAS, 3., 1991, Recife. Resumos... Recife: SEB, 1991. v. 1. 234.| Biblioteca(s): Embrapa Soja. |
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| 14. | | MORALES, L.; MOSCARDI, F.; SÓSA-GOMEZ, D. R.; PARO, F. E.; SOLDORIO, I. L. Fluorescent brighteners improve Anticarsia gemmatalis (Lepidoptera: Noctuidae) nucleopolyhedrovirus (AgMNPV) activity on AgMNPV-susceptible and resistant strains of the insect. Biological Control, Orlando, v. 20, n. 3, p. 247-253, Mar. 2001.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: Internacional - B |
| Biblioteca(s): Embrapa Soja. |
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| 15. | | MORALES, L.; VENTURA, M. U.; MOSCARDI, F.; PARO, F.; SOLDORIO, I. Efeito do extrato de flor de Melia azedarach em Anticarsia gemmatalis, e em mistura com o seu virus de poliedrose nuclear. In: CONGRESSO BRASILEIRO DE ENTOMOLOGIA, 16.; ENCONTRO NACIONAL DE FITOSSANITARISTAS, 7., 1997, Salvador. Resumos... Salvador: Sociedade Entomologica do Brasil / Cruz das Almas: EMBRAPA-CNPMF, 1997. p.110-111.| Biblioteca(s): Embrapa Soja. |
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| 17. | | MOSCARDI, F.; SOSA-GÓMEZ, D. R.; MORALES, L.; PARO, F. E.; SOLDORIO, I. L. Selection for resistance in the laboratory to the nucleopolyhedrovirus of Anticarsia gemmatalis (Lepidoptera: Noctuidae) (AgMNPV). In: CONGRESSO NACIONAL DE CONTROL BIOLÓGICO, 26., 2003, Guadalajara. Memorias. [S.l.]: Sociedad Mexicana de Control Biológico, [2003]. p. 319-322. Editado por Marcelino Vázquez Garcia, J. Francisco Pérez Domínguez, Karla H. Ibarra Cortés, Claudia I. Balpuesta León, Jorge Rafael Vázquez Reyes, Jesús Cervantes Ríos, Nelly Ibarra Frías.| Biblioteca(s): Embrapa Soja. |
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| 19. | | MORALES, L.; MOSCARDI, F.; KASTELIC, J. G.; SÓSA-GOMEZ, D. R.; PARO, F. E.; SOLDORIO, I. L. Suscetibilidade de Anticarsia gemmatalis Hubner e Chrysodeixis includens (Walker) (Lepidoptera: Noctuidae), a Bacillus thuringiensis (Berliner). Anais da Sociedade Entomologica do Brasil, Londrina, v. 24, n. 3, p. 593-598, dez. 1995.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: Nacional - B |
| Biblioteca(s): Embrapa Soja. |
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| 20. | | MEDEIROS, U. K. L.; PEDRINI, M. R. S.; ANDRADE JÚNIOR, W. M.; PARO, F.; SOLDÓRIO, I. L.; MOSCARDI, F.; SOUZA, M. L.; MEDEIROS, M. E. D. Avaliação da qualidade do inseticida biológico Baculovírus anticarsia obtido a partir do processo de secagem em leito de jorro. In: SIMPÓSIO DE CONTROLE BIOLÓGICO, 9., 2005, Recife. Anais... Recife, 2005. p. 190.| Biblioteca(s): Embrapa Soja. |
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| Registros recuperados : 22 | |
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| Nenhum registro encontrado para a expressão de busca informada. |
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