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 | Acesso ao texto completo restrito à biblioteca da Embrapa Gado de Leite. Para informações adicionais entre em contato com rosangela.lacerda@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Gado de Leite. |
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Data corrente: |
10/11/2022 |
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Data da última atualização: |
10/11/2022 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
CASCARDO, B.; BERNARDES, C.; SOUZA, G. N. de; SILVA, K. M.; PIRES, N. R.; ALENCAR, N. X. de; LESSA, D. A. B. |
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Afiliação: |
BIANCA CASCARDO, Universidade Federal Fluminense; CAMILA BERNARDES, Universidade Federal Fluminense; GUILHERME NUNES DE SOUZA, CNPGL; KATIA M. SILVA, Universidade Federal Fluminense; NATALIA R. PIRES, Universidade Federal Fluminense; NAYRO XAVIER DE ALENCAR, Universidade Federal Fluminense; DANIEL A. B. LESSA, Universidade Federal Fluminense. |
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Título: |
Diagnostic value of tracheal wash cytology for monitoring exercise-induced pulmonary hemorrhage in thoroughbred racehorses. |
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Ano de publicação: |
2022 |
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Fonte/Imprenta: |
Journal of Equine Veterinary Science, v. 118, 104128, 2022. |
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DOI: |
https://doi.org/10.1016/j.jevs.2022.104128 |
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Idioma: |
Inglês |
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Conteúdo: |
Lower airway cytology has been proposed as a complementary diagnostic method to confirm the presence and quantifying the severity of exercise-induced pulmonary hemorrhage (EIPH). Bronchoalveolar lavage is usually preferred over tracheal wash (TW), yet the need for sedation imposes as a limitation for active sport horses in addition to be a highly invasive technique. This study aims to evaluate the diagnostic value of TW with Total Hemosiderin Score (THS) for monitoring EIPH in active Thoroughbred racehorses. A sampling of 47 randomly selected Thoroughbreds were endoscopically examined for EIPH grading 30 to 60 minutes after competing in an official race and then classified as Group 1 (EIPH-negative), Group 2 (EIPH-positive) or Group 3 (furosemide users). Tracheal wash fluids (TWFs) were collected from 24 to 30 hours later and smears were stained for differential cell count and hemosiderophage grading and counting to calculate THS. Differential cell counts were compared by the median test. Comparisons between mean THS values by EIPH grade and by group were compared by the Mann-Whitney test and ANOVA, respectively. Test performance criteria were determined with a contingency table. It was not possible to establish a THS cut-off point but statistical results showed that, at THS stand view, all groups had similar results despite their EIPH grades. Most animals showed no signs of neutrophilic inflammation, but haemosiderophages were found even on a first-time runner from Group 1. Thus, TW can detect evidence of lung bleeding even on horses with no history of EIPH. The implementation of TW analysis to diagnose EIPH in racehorses is promising, as TW is both low-cost and a less invasive tool. MenosLower airway cytology has been proposed as a complementary diagnostic method to confirm the presence and quantifying the severity of exercise-induced pulmonary hemorrhage (EIPH). Bronchoalveolar lavage is usually preferred over tracheal wash (TW), yet the need for sedation imposes as a limitation for active sport horses in addition to be a highly invasive technique. This study aims to evaluate the diagnostic value of TW with Total Hemosiderin Score (THS) for monitoring EIPH in active Thoroughbred racehorses. A sampling of 47 randomly selected Thoroughbreds were endoscopically examined for EIPH grading 30 to 60 minutes after competing in an official race and then classified as Group 1 (EIPH-negative), Group 2 (EIPH-positive) or Group 3 (furosemide users). Tracheal wash fluids (TWFs) were collected from 24 to 30 hours later and smears were stained for differential cell count and hemosiderophage grading and counting to calculate THS. Differential cell counts were compared by the median test. Comparisons between mean THS values by EIPH grade and by group were compared by the Mann-Whitney test and ANOVA, respectively. Test performance criteria were determined with a contingency table. It was not possible to establish a THS cut-off point but statistical results showed that, at THS stand view, all groups had similar results despite their EIPH grades. Most animals showed no signs of neutrophilic inflammation, but haemosiderophages were found even on a first-time runner from Group 1.... Mostrar Tudo |
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Palavras-Chave: |
Airways; Haemosiderophages; Prussian Blue; Pulmonary bleeding; THS. |
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Thesagro: |
Cavalo de Corrida; Citologia; Eqüino; Hemorragia; Pulmão. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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Marc: |
LEADER 02669naa a2200325 a 4500
001 2148180
005 2022-11-10
008 2022 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1016/j.jevs.2022.104128$2DOI
100 1 $aCASCARDO, B.
245 $aDiagnostic value of tracheal wash cytology for monitoring exercise-induced pulmonary hemorrhage in thoroughbred racehorses.$h[electronic resource]
260 $c2022
520 $aLower airway cytology has been proposed as a complementary diagnostic method to confirm the presence and quantifying the severity of exercise-induced pulmonary hemorrhage (EIPH). Bronchoalveolar lavage is usually preferred over tracheal wash (TW), yet the need for sedation imposes as a limitation for active sport horses in addition to be a highly invasive technique. This study aims to evaluate the diagnostic value of TW with Total Hemosiderin Score (THS) for monitoring EIPH in active Thoroughbred racehorses. A sampling of 47 randomly selected Thoroughbreds were endoscopically examined for EIPH grading 30 to 60 minutes after competing in an official race and then classified as Group 1 (EIPH-negative), Group 2 (EIPH-positive) or Group 3 (furosemide users). Tracheal wash fluids (TWFs) were collected from 24 to 30 hours later and smears were stained for differential cell count and hemosiderophage grading and counting to calculate THS. Differential cell counts were compared by the median test. Comparisons between mean THS values by EIPH grade and by group were compared by the Mann-Whitney test and ANOVA, respectively. Test performance criteria were determined with a contingency table. It was not possible to establish a THS cut-off point but statistical results showed that, at THS stand view, all groups had similar results despite their EIPH grades. Most animals showed no signs of neutrophilic inflammation, but haemosiderophages were found even on a first-time runner from Group 1. Thus, TW can detect evidence of lung bleeding even on horses with no history of EIPH. The implementation of TW analysis to diagnose EIPH in racehorses is promising, as TW is both low-cost and a less invasive tool.
650 $aCavalo de Corrida
650 $aCitologia
650 $aEqüino
650 $aHemorragia
650 $aPulmão
653 $aAirways
653 $aHaemosiderophages
653 $aPrussian Blue
653 $aPulmonary bleeding
653 $aTHS
700 1 $aBERNARDES, C.
700 1 $aSOUZA, G. N. de
700 1 $aSILVA, K. M.
700 1 $aPIRES, N. R.
700 1 $aALENCAR, N. X. de
700 1 $aLESSA, D. A. B.
773 $tJournal of Equine Veterinary Science$gv. 118, 104128, 2022.
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