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Registro Completo |
Biblioteca(s): |
Embrapa Agroindústria de Alimentos. |
Data corrente: |
27/05/2021 |
Data da última atualização: |
28/09/2021 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
THEODORO, J. M. V.; MARTINEZ, O. D. M.; GRANCIERI, M.; TOLEDO, R. C. L.; BINOTI, M. L.; MARTINS, A. M. D.; CARVALHO, C. W. P. de; LISBOA, P. C.; MARTINO, H. S. |
Afiliação: |
JAQUELINE MACIEL VIEIRA THEODORO, UFV; OSCAR DAVID MEDINA MARTINEZ, UFV; MARIANA GRANCIERI, UFV; RENATA CELI LOPES TOLEDO, UFV; MIRELLA LIMA BINOTI, UFV; AMANDA M. DIAS MARTINS, UFRRJ; CARLOS WANDERLEI PILER DE CARVALHO, CTAA; PATRÍCIA CRISTINA LISBOA, Universidade Estadual do Rio de Janeiro; HÉRCIA STAMPINI DUARTE MARTINO, UFV. |
Título: |
Germinated millet flour (Pennisetum Glaucum (L.) R. BR.) improves adipogenesis and glucose metabolism and maintains thyroid function in vivo. |
Ano de publicação: |
2021 |
Fonte/Imprenta: |
Food & Function, v. 12, p. 6083-6090, 2021. |
DOI: |
https://doi.org/10.1039/D0FO03388J |
Idioma: |
Inglês |
Conteúdo: |
This study investigated the effects of germinated millet flour on adipogenesis, insulin resistance, glucose tolerance and thyroid function in Wistar rats fed with a high-fat high-fructose diet (HFHF). The experiment was divided into two phases. Phase 1: control group, which received AIN-93M diet (n = 10) and HFHF group (n = 20), which received a diet rich in saturated fat (31%) and fructose (20%), for eight weeks. Phase 2: intervention: the control group maintained the AIN-93M diet (n = 10) and the HFHF group was divided into two groups: the HFHF (n = 10) and the germinated millet group (n = 10), for 10 weeks. The germinated millet flour maintained (p>0, 05) the plasma levels of thyroid hormones, increased (p<0.05) the protein kinase B (AKT) mRNA expression and the phospho-AKT1 protein concentration, the phosphofructokinase (PFK) mRNA and activated protein kinase (AMPK) mRNA expression, and the brown adipose tissue and reduced (p<0.05) the glucose triglyceride index (TyG), glucose, insulin and hypercorticosteronemia, compared to the HFHF group. These effects contributed to reduce the gluconeogenesis, hyperinsulinemia and adiposity. Thus, germinated millet flour is a good alternative for modulating the adipogenesis and glucose metabolism, without interfering with the thyroid hormones, in rats with an insulin resistance condition with a high-fat high-fructose diet. |
Thesaurus Nal: |
Food technology. |
Categoria do assunto: |
-- |
Marc: |
LEADER 02176naa a2200241 a 4500 001 2132068 005 2021-09-28 008 2021 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.1039/D0FO03388J$2DOI 100 1 $aTHEODORO, J. M. V. 245 $aGerminated millet flour (Pennisetum Glaucum (L.) R. BR.) improves adipogenesis and glucose metabolism and maintains thyroid function in vivo.$h[electronic resource] 260 $c2021 520 $aThis study investigated the effects of germinated millet flour on adipogenesis, insulin resistance, glucose tolerance and thyroid function in Wistar rats fed with a high-fat high-fructose diet (HFHF). The experiment was divided into two phases. Phase 1: control group, which received AIN-93M diet (n = 10) and HFHF group (n = 20), which received a diet rich in saturated fat (31%) and fructose (20%), for eight weeks. Phase 2: intervention: the control group maintained the AIN-93M diet (n = 10) and the HFHF group was divided into two groups: the HFHF (n = 10) and the germinated millet group (n = 10), for 10 weeks. The germinated millet flour maintained (p>0, 05) the plasma levels of thyroid hormones, increased (p<0.05) the protein kinase B (AKT) mRNA expression and the phospho-AKT1 protein concentration, the phosphofructokinase (PFK) mRNA and activated protein kinase (AMPK) mRNA expression, and the brown adipose tissue and reduced (p<0.05) the glucose triglyceride index (TyG), glucose, insulin and hypercorticosteronemia, compared to the HFHF group. These effects contributed to reduce the gluconeogenesis, hyperinsulinemia and adiposity. Thus, germinated millet flour is a good alternative for modulating the adipogenesis and glucose metabolism, without interfering with the thyroid hormones, in rats with an insulin resistance condition with a high-fat high-fructose diet. 650 $aFood technology 700 1 $aMARTINEZ, O. D. M. 700 1 $aGRANCIERI, M. 700 1 $aTOLEDO, R. C. L. 700 1 $aBINOTI, M. L. 700 1 $aMARTINS, A. M. D. 700 1 $aCARVALHO, C. W. P. de 700 1 $aLISBOA, P. C. 700 1 $aMARTINO, H. S. 773 $tFood & Function$gv. 12, p. 6083-6090, 2021.
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Embrapa Agroindústria de Alimentos (CTAA) |
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1. |  | PICOLI, T.; PETER, C. M.; VARGAS, G. D.; HUBNER, S. O.; LIMA, M. de; FISCHER, G. Potencial antiviral e virucida da melitina e apamina contra herpesvírus bovino tipo 1 e vírus da diarreia viral bovina. Pesquisa Veterinária Brasileira, Rio de Janeiro, v. 38, n. 4, p. 595-604, abril 2018 Título em inglês: Antiviral and virucidal potential of melittin and apamin against bovine herpesvirus type 1 and bovine viral diarrhea virus.Biblioteca(s): Embrapa Unidades Centrais. |
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2. |  | MUNHOZ, L. S.; VARGAS, G. D.; FISCHER, G.; LIMA, M. de; ESTEVES, P. A.; HÜBNER, S. de O. Avian IgY antibodies: characteristics and applications in immunodiagnostic. Ciência Rural, Santa Maria, v. 44, n. 1, p. 153-160, 2014.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
Biblioteca(s): Embrapa Suínos e Aves. |
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3. |  | CATALAN, A. A. da S.; AVILA, V. S. de; LOPES, L. L.; MONTAGNER, P.; VARGAS, G. D.; XAVIER, E. G.; ROLL, V. F. B. Perfil metabólico, hematológico e comportamental de poedeiras suplementadas com Panax ginseng. Archivos de Zootecnia, Córdoba, v. 62, n. 237, p. 89-100, 2013.Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 2 |
Biblioteca(s): Embrapa Suínos e Aves. |
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4. |  | FINGER, P. F.; DUMMER, L. A.; CUNHA, C. E. P.; CONCEIÇÃO, F. R.; MUNHOZ, L. S.; NUNES, C, F.; VIANCELLI, A.; ESTEVES, P. A.; FISCHER, G.; VARGAS, G. D.; HÜBNER, S. O. Construction of expression vector pPICZalfaB for cloning of S1 glycoprotein gene of the infectious bronchitis virus (IBV) in Pichia pastoris. Virus Reviews and Research, v. 15, supl. 1, p. 305, oct. 2010. Trabalho apresentado no NATIONAL MEETING OF VIROLOGY, 21.; MERCOSUL MEETING OF VIROLOGY, 5. Projeto/Plano de Ação: 03.09.01800-01.Tipo: Resumo em Anais de Congresso |
Biblioteca(s): Embrapa Suínos e Aves. |
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