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Registro Completo |
Biblioteca(s): |
Embrapa Amazônia Oriental. |
Data corrente: |
05/10/2017 |
Data da última atualização: |
20/05/2022 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
TORMA, P. do C. M. R.; BRASIL, A. V. S.; CARVALHO, A. V.; JABLONSKI, A.; RABELO, T. K.; MOREIRA, J. C. F.; GELAIN, D. P.; FLÔRES, S. H.; AUGUSTI, P. R.; RIOS, A. de O. |
Afiliação: |
Priscila do Carmo Marchioro Raupp Torma, UFRGS; Allana Von Sulzback Brasil, UFRGS; ANA VANIA CARVALHO, CPATU; André Jablonski, UFRGS; Thallita Kelly Rabelo, UFRGS; José Cláudio Fonseca Moreira, UFRGS; Daniel Pens Gelain, UFRGS; Simone Hickmann Flôres, UFRGS; Paula Rossini Augusti, UFRGS; Alessandro de Oliveira Rios, UFRGS. |
Título: |
Hydroethanolic extracts from different genotypes of açaí (Euterpe oleracea) presented antioxidant potential and protected human neuron-like cells (SH-SY5Y). |
Ano de publicação: |
2017 |
Fonte/Imprenta: |
Food Chemistry, v. 222, p. 94-104, May 2017. |
DOI: |
http://dx.doi.org/10.1016/j.foodchem.2016.12.006 |
Idioma: |
Inglês |
Conteúdo: |
Fruit breeding programs have resulted in bioactive compounds increase and health effects. Thus, this study aimed to evaluate the antioxidant activity and neuroprotective effects of the hydroethanolic extracts from six açaí (Euterpe oleracea) genotypes using ABTS, deoxyribose, and glutathione oxidation assays, as well as, SH-SY5Y cells insulted with H2O2. L22P13 genotype showed the highest total content of anthocyanins, while L06P13 showed a high content of total carotenoids. However, the genotypes showed no difference in the antioxidant activity by ABTS and deoxyribose assays. The hydroethanolic extracts from different genotypes of açaí showed a protective effect (13?62%) on SH-SY5Y cells insulted by H2O2 at a concentration of 50 lg/mL by DCFH-DA assay. Except L04P16, no genotypes showed cytotoxicity in the SRB assay. These results indicate that açaí genotypes have antioxidant effect against reactive species generated in SH-SY5Y cells, suggesting a neuroprotective effect of the hydroethanolic extracts from these fruits. |
Palavras-Chave: |
Antocianinas; Atividade antioxidante; Carotenóides. |
Thesagro: |
Açaí. |
Categoria do assunto: |
Q Alimentos e Nutrição Humana |
Marc: |
LEADER 01971naa a2200289 a 4500 001 2076774 005 2022-05-20 008 2017 bl uuuu u00u1 u #d 024 7 $ahttp://dx.doi.org/10.1016/j.foodchem.2016.12.006$2DOI 100 1 $aTORMA, P. do C. M. R. 245 $aHydroethanolic extracts from different genotypes of açaí (Euterpe oleracea) presented antioxidant potential and protected human neuron-like cells (SH-SY5Y).$h[electronic resource] 260 $c2017 520 $aFruit breeding programs have resulted in bioactive compounds increase and health effects. Thus, this study aimed to evaluate the antioxidant activity and neuroprotective effects of the hydroethanolic extracts from six açaí (Euterpe oleracea) genotypes using ABTS, deoxyribose, and glutathione oxidation assays, as well as, SH-SY5Y cells insulted with H2O2. L22P13 genotype showed the highest total content of anthocyanins, while L06P13 showed a high content of total carotenoids. However, the genotypes showed no difference in the antioxidant activity by ABTS and deoxyribose assays. The hydroethanolic extracts from different genotypes of açaí showed a protective effect (13?62%) on SH-SY5Y cells insulted by H2O2 at a concentration of 50 lg/mL by DCFH-DA assay. Except L04P16, no genotypes showed cytotoxicity in the SRB assay. These results indicate that açaí genotypes have antioxidant effect against reactive species generated in SH-SY5Y cells, suggesting a neuroprotective effect of the hydroethanolic extracts from these fruits. 650 $aAçaí 653 $aAntocianinas 653 $aAtividade antioxidante 653 $aCarotenóides 700 1 $aBRASIL, A. V. S. 700 1 $aCARVALHO, A. V. 700 1 $aJABLONSKI, A. 700 1 $aRABELO, T. K. 700 1 $aMOREIRA, J. C. F. 700 1 $aGELAIN, D. P. 700 1 $aFLÔRES, S. H. 700 1 $aAUGUSTI, P. R. 700 1 $aRIOS, A. de O. 773 $tFood Chemistry$gv. 222, p. 94-104, May 2017.
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1. |  | SOUSA, N. A.; OLIVEIRA, G. A. L.; OLIVEIRA, A. P. de; LOPES, A. L. F.; ILES, B.; NOGUEIRA, K. M.; ARAÚJO, T. S. L.; SOUZA, L. K. M.; ARAÚJO, A. R.; RAMOS-JESUS, J.; PLÁCIDO, A.; AMARAL, C.; CAMPELO, Y. D. M.; BARBOSA, E. A.; PORTUGAL, C. C.; SOCODATO, R.; LOBO, A.; RELVAS, J.; BEMQUERER, M.; EATON, P.; LEITE, J. R. S. A; MEDEIROS, J. V. R. Novel ocellatin peptides mitigate LPS-induced ROS formation and NF-kB activation in microglia and hippocampal neurons. Scientific Reports, v. 10, n. 1, article 2696, 2020.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
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