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 | Acesso ao texto completo restrito à biblioteca da Embrapa Pecuária Sudeste. Para informações adicionais entre em contato com cppse.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Pecuária Sudeste. |
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Data corrente: |
20/10/2016 |
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Data da última atualização: |
07/11/2018 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
PEREIRA, G. L.; MATTEIS, R. de; REGITANO, L. C. de A.; CHARDULO, L. A. L.; CURI, R. A. |
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Afiliação: |
GUILHERME L. PEREIRA, UNESP; RAFAEL DE MATTEIS, UNESP; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE; LUÍS ARTUR L. CHARDULO, UNESP; ROGÉRIO A. CURI, UNESP. |
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Título: |
MSTN, CKM, and DMRT3 gene variants in different lines of quarter horses. |
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Ano de publicação: |
2016 |
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Fonte/Imprenta: |
Journal of Equine Veterinary Science, v.39, p.33-37, apr. 2016. |
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Volume: |
39 |
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Páginas: |
33-37 |
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DOI: |
http://dx.doi.org/10.1016/j.jevs.2015.09.001 |
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Idioma: |
Inglês |
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Conteúdo: |
and creatine kinase muscle (CKM) (g.22999655C>A) genes have been associated with optimum racing distance and muscle development and racing performance in Thoroughbred horses, respectively. Considering that, since its formation, the Quarter Horse breed has received important genetic influence from the English breed, the genes cited become important candidates for athletic performance in the racing line of the American breed. An SNP in the equine doublesex and mab-3-related transcription factor 3 (DMRT3) gene (g.22999655C>A) has been described, which is responsible for the gait phenotype in homozygous individuals. Using a sample of 296 Quarter Horses of the racing line and 68 animals of the cutting line, the objective of this study was to compare the frequencies of the three SNPs cited above between a random subsample of animals of the cutting line (n ¼ 20) and animals with extreme phenotypes for racing performance (n ¼ 20 per extreme phenotype). The MSTN SNP showed practically no variation, with the observation of only one heterozygous animal (CT) in the cutting line, suggesting that this gene has been under great selective pressure within the racing segment. The CKM gene variant studied was found to be polymorphic, but no significant associates were observed between its alleles and the different lines or groups. Two animals carrying the CA heterozygous DMRT3 genotype were identified in the group with poor racing performance and one in the cutting line, indicating that this variant can be a limiting factor for the development of greater speeds. Menosand creatine kinase muscle (CKM) (g.22999655C>A) genes have been associated with optimum racing distance and muscle development and racing performance in Thoroughbred horses, respectively. Considering that, since its formation, the Quarter Horse breed has received important genetic influence from the English breed, the genes cited become important candidates for athletic performance in the racing line of the American breed. An SNP in the equine doublesex and mab-3-related transcription factor 3 (DMRT3) gene (g.22999655C>A) has been described, which is responsible for the gait phenotype in homozygous individuals. Using a sample of 296 Quarter Horses of the racing line and 68 animals of the cutting line, the objective of this study was to compare the frequencies of the three SNPs cited above between a random subsample of animals of the cutting line (n ¼ 20) and animals with extreme phenotypes for racing performance (n ¼ 20 per extreme phenotype). The MSTN SNP showed practically no variation, with the observation of only one heterozygous animal (CT) in the cutting line, suggesting that this gene has been under great selective pressure within the racing segment. The CKM gene variant studied was found to be polymorphic, but no significant associates were observed between its alleles and the different lines or groups. Two animals carrying the CA heterozygous DMRT3 genotype were identified in the group with poor racing performance and one in the cutting line, indicating that this v... Mostrar Tudo |
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Palavras-Chave: |
Cavalo de um quarto; Equine; Gens variantes; SNP. |
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Thesagro: |
Eqüino. |
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Categoria do assunto: |
G Melhoramento Genético |
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Marc: |
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024 7 $ahttp://dx.doi.org/10.1016/j.jevs.2015.09.001$2DOI
100 1 $aPEREIRA, G. L.
245 $aMSTN, CKM, and DMRT3 gene variants in different lines of quarter horses.$h[electronic resource]
260 $c2016
300 $a33-37 39
490 $v39
520 $aand creatine kinase muscle (CKM) (g.22999655C>A) genes have been associated with optimum racing distance and muscle development and racing performance in Thoroughbred horses, respectively. Considering that, since its formation, the Quarter Horse breed has received important genetic influence from the English breed, the genes cited become important candidates for athletic performance in the racing line of the American breed. An SNP in the equine doublesex and mab-3-related transcription factor 3 (DMRT3) gene (g.22999655C>A) has been described, which is responsible for the gait phenotype in homozygous individuals. Using a sample of 296 Quarter Horses of the racing line and 68 animals of the cutting line, the objective of this study was to compare the frequencies of the three SNPs cited above between a random subsample of animals of the cutting line (n ¼ 20) and animals with extreme phenotypes for racing performance (n ¼ 20 per extreme phenotype). The MSTN SNP showed practically no variation, with the observation of only one heterozygous animal (CT) in the cutting line, suggesting that this gene has been under great selective pressure within the racing segment. The CKM gene variant studied was found to be polymorphic, but no significant associates were observed between its alleles and the different lines or groups. Two animals carrying the CA heterozygous DMRT3 genotype were identified in the group with poor racing performance and one in the cutting line, indicating that this variant can be a limiting factor for the development of greater speeds.
650 $aEqüino
653 $aCavalo de um quarto
653 $aEquine
653 $aGens variantes
653 $aSNP
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700 1 $aREGITANO, L. C. de A.
700 1 $aCHARDULO, L. A. L.
700 1 $aCURI, R. A.
773 $tJournal of Equine Veterinary Science$gv.39, p.33-37, apr. 2016.
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| 3. |  | SILVA JUNIOR, J. J.; COELHO, E. F.; SANT'ANA, J. A. V.; SANTANA JUNIOR, E. B.; PAMPONET, A. M.; NASCIMENTO JUNIOR, A. L. Efeito da fertirrigação com manipueira na produtividade da banana da Terra (Musa paradisiaca group Cavendish). In: CONGRESSO NACIONAL DE IRRIGAÇÃO E DRENAGEM, 19., 2009, Montes Claros. Os efeitos multiplicadores da agricultura irrigada: anais. Montes Claros: ABID, 2009. 1 CD-ROM. pdf109.| Tipo: Artigo em Anais de Congresso / Nota Técnica |
| Biblioteca(s): Embrapa Mandioca e Fruticultura. |
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| 4. | | SILVA JUNIOR, J. J.; COELHO, E. F.; SANT'ANA, J. A. V.; SANTANA JUNIOR, E. B.; PAMPONET, A. M.; NASCIMENTO JUNIOR, A. L. Efeito da fertirrigação com manipueira no solo com banana da Terra. In: CONGRESSO NACIONAL DE IRRIGAÇÃO E DRENAGEM, 19., 2009, Montes Claros. Os efeitos multiplicadores da agricultura irrigada: anais. Montes Claros: ABID, 2009. 1 CD-ROM. pdf 96.| Tipo: Artigo em Anais de Congresso / Nota Técnica |
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