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 | Acesso ao texto completo restrito à biblioteca da Embrapa Suínos e Aves. Para informações adicionais entre em contato com cnpsa.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Suínos e Aves. |
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Data corrente: |
15/10/2015 |
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Data da última atualização: |
15/03/2016 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
GODOY, T. F.; MOREIRA, G. C. M.; BOSCHIERO, C.; GHEYAS, A. A.; GASPARIN, G.; PADUAN, M.; ANDRADE, S. C. S.; MONTENEGRO, H.; BURT, D. W.; LEDUR, M. C.; COUTINHO, L. L. |
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Afiliação: |
THAYS FERNANDA GODOY, ESALQ; GABRIEL COSTA MONTEIRO MOREIRA, ESALQ; CLARISSA BOSCHIERO, ESALQ; ALMAS A. GHEYAS, University of Edinburgh; GUSTAVO GASPARIN, ESALQ; MARCELA PADUAN, ESALQ; SONIA CRISTINA DA SILVA ANDRADE, ESALQ; HORACIO MONTENEGRO, ESALQ; DAVID W. BURT, University of Edinburgh; MONICA CORREA LEDUR, CNPSA; LUIZ LEHMANN COUTINHO, ESALQ. |
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Título: |
SNP and INDEL detection in a QTL region on chicken chromosome 2 associated with muscle deposition. |
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Ano de publicação: |
2015 |
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Fonte/Imprenta: |
Animal Genetics, v. 6, n. 2, p. 158-163, 2015. |
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DOI: |
10.1111/age.12271 |
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Idioma: |
Inglês |
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Conteúdo: |
Genetic improvement is important for the poultry industry, contributing to increased efficiency of meat production and quality. Because breast muscle is the most valuable part of the chicken carcass, knowledge of polymorphisms influencing this trait can help breeding programs. Therefore, the complete genome of 18 chickens from two different experimental lines (broiler and layer) from EMBRAPA was sequenced, and SNPs and INDELs were detected in a QTL region for breast muscle deposition on chicken chromosome 2 between microsatellite markers MCW0185 and MCW0264 (105 849?112 649 kb). Initially, 94 674 unique SNPs and 10 448 unique INDELs were identified in the target region. After quality filtration, 77% of the SNPs (85 765) and 60% of the INDELs (7828) were retained. The studied region contains 66 genes, and functional annotation of the filtered variants identified 517 SNPs and three INDELs in exonic regions. Of these, 357 SNPs were classified as synonymous, 153 as nonsynonymous, three as stopgain, four INDELs as frameshift and three INDELs as nonframeshift. These exonic mutations were identified in 37 of the 66 genes from the target region, three of which are related to muscle development (DTNA, RB1CC1 and MOS). Fifteen non-tolerated SNPs were detected in several genes (MEP1B, PRKDC, NSMAF, TRAPPC8, SDR16C5, CHD7, ST18 and RB1CC1). These loss-of-function and exonic variants present in genes related to muscle development can be considered candidate variants for further studies in chickens. Further association studies should be performed with these candidate mutations as should validation in commercial populations to allow a better explanation of QTL effects. MenosGenetic improvement is important for the poultry industry, contributing to increased efficiency of meat production and quality. Because breast muscle is the most valuable part of the chicken carcass, knowledge of polymorphisms influencing this trait can help breeding programs. Therefore, the complete genome of 18 chickens from two different experimental lines (broiler and layer) from EMBRAPA was sequenced, and SNPs and INDELs were detected in a QTL region for breast muscle deposition on chicken chromosome 2 between microsatellite markers MCW0185 and MCW0264 (105 849?112 649 kb). Initially, 94 674 unique SNPs and 10 448 unique INDELs were identified in the target region. After quality filtration, 77% of the SNPs (85 765) and 60% of the INDELs (7828) were retained. The studied region contains 66 genes, and functional annotation of the filtered variants identified 517 SNPs and three INDELs in exonic regions. Of these, 357 SNPs were classified as synonymous, 153 as nonsynonymous, three as stopgain, four INDELs as frameshift and three INDELs as nonframeshift. These exonic mutations were identified in 37 of the 66 genes from the target region, three of which are related to muscle development (DTNA, RB1CC1 and MOS). Fifteen non-tolerated SNPs were detected in several genes (MEP1B, PRKDC, NSMAF, TRAPPC8, SDR16C5, CHD7, ST18 and RB1CC1). These loss-of-function and exonic variants present in genes related to muscle development can be considered candidate variants for further studies i... Mostrar Tudo |
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Palavras-Chave: |
Músculo de peito; SNPs. |
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Thesagro: |
Frango; Melhoramento genético animal; Mutação. |
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Thesaurus Nal: |
Animal genetics; Breast muscle; Broiler chickens; Genetic polymorphism; Quantitative trait loci; Single nucleotide polymorphism. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02784naa a2200385 a 4500
001 2026548
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008 2015 bl uuuu u00u1 u #d
024 7 $a10.1111/age.12271$2DOI
100 1 $aGODOY, T. F.
245 $aSNP and INDEL detection in a QTL region on chicken chromosome 2 associated with muscle deposition.$h[electronic resource]
260 $c2015
520 $aGenetic improvement is important for the poultry industry, contributing to increased efficiency of meat production and quality. Because breast muscle is the most valuable part of the chicken carcass, knowledge of polymorphisms influencing this trait can help breeding programs. Therefore, the complete genome of 18 chickens from two different experimental lines (broiler and layer) from EMBRAPA was sequenced, and SNPs and INDELs were detected in a QTL region for breast muscle deposition on chicken chromosome 2 between microsatellite markers MCW0185 and MCW0264 (105 849?112 649 kb). Initially, 94 674 unique SNPs and 10 448 unique INDELs were identified in the target region. After quality filtration, 77% of the SNPs (85 765) and 60% of the INDELs (7828) were retained. The studied region contains 66 genes, and functional annotation of the filtered variants identified 517 SNPs and three INDELs in exonic regions. Of these, 357 SNPs were classified as synonymous, 153 as nonsynonymous, three as stopgain, four INDELs as frameshift and three INDELs as nonframeshift. These exonic mutations were identified in 37 of the 66 genes from the target region, three of which are related to muscle development (DTNA, RB1CC1 and MOS). Fifteen non-tolerated SNPs were detected in several genes (MEP1B, PRKDC, NSMAF, TRAPPC8, SDR16C5, CHD7, ST18 and RB1CC1). These loss-of-function and exonic variants present in genes related to muscle development can be considered candidate variants for further studies in chickens. Further association studies should be performed with these candidate mutations as should validation in commercial populations to allow a better explanation of QTL effects.
650 $aAnimal genetics
650 $aBreast muscle
650 $aBroiler chickens
650 $aGenetic polymorphism
650 $aQuantitative trait loci
650 $aSingle nucleotide polymorphism
650 $aFrango
650 $aMelhoramento genético animal
650 $aMutação
653 $aMúsculo de peito
653 $aSNPs
700 1 $aMOREIRA, G. C. M.
700 1 $aBOSCHIERO, C.
700 1 $aGHEYAS, A. A.
700 1 $aGASPARIN, G.
700 1 $aPADUAN, M.
700 1 $aANDRADE, S. C. S.
700 1 $aMONTENEGRO, H.
700 1 $aBURT, D. W.
700 1 $aLEDUR, M. C.
700 1 $aCOUTINHO, L. L.
773 $tAnimal Genetics$gv. 6, n. 2, p. 158-163, 2015.
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Registro original: |
Embrapa Suínos e Aves (CNPSA) |
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Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
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| Registros recuperados : 29 | |
| 10. |  | BACCA, T.; LIMA, E. R.; PICANÇO, M. C.; GUEDES, R. N. C.; VIANA, J. H. M. Optimum spacing of pheromone traps for monitoring the coffee leaf miner Leucoptera coffeella. Entomologia Experimentalis et Applicata, Dordrecht, v. 119, n. 1, p. 39-45, 2006.| Tipo: Artigo em Periódico Indexado |
| Biblioteca(s): Embrapa Milho e Sorgo. |
|    |
| 11. | | BACCA, T.; LIMA, E. R.; PICANÇO, M. C.; GUEDES, R. N. C.; VIANA, J. H. M. Sampling plan for the coffe leaf miner Leucoptera coffeella with sex pheromone traps. Journal of Apllied Entomology, Hamburg, v. 132, n. 6, p. 430-438, 2008.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: Internacional - A |
| Biblioteca(s): Embrapa Milho e Sorgo. |
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| 12. | | LIMA, J. L. S. de; CAVALCANTI, N. de B.; LIMA, E. R. de; CARVALHO, K. M. de. Levantamento fitoecologico do municipio de Petrolina, PE. In: CONGRESSO NACIONAL DE BOTANICA, 47., 1996, Nova Friburgo, RJ. Resumos... Nova Friburgo: SBB, 1996. p. 190.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Semiárido. |
|  |
| 13. | | SILVA, R. B.; ZANUNCIO, J. C.; SERRÃO, J. E.; LIMA, E. R.; FIGUEIREDO, M. L. C.; CRUZ, I. Suitability of different artificial diets for development and survival of stages of the predaceous ladybird beetle Eriopis connexa. Phytoparasitica, Bet Dagan, v. 37, p. 115-123, 2009.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 1 |
| Biblioteca(s): Embrapa Milho e Sorgo. |
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| 14. | | SILVA, F. W. S.; ELLIOT, S. L.; VIOL, D. L.; FARIA, S. V.; LIMA, E. R. de; VALICENTE, F. H. Plasticidade fenotípica e resistência a doenças em Anticarsia gemmatalis. In: CONGRESSO BRASILEIRO DE ENTOMOLOGIA, 23., 2010, Natal. Anais... Natal: Sociedade Brasileira de Entomologia, 2010. 1 CD-ROM.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Milho e Sorgo. |
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| 15. | | FRANCISCO, P. R. M.; CHAVES, I. de B.; CHAVES, L. H. G.; LIMA, E. R. V. de; BRANDAO, Z. N.; SILVA, B. B. da. Análise espectral e avaliação de índices de vegetação para o mapeamento da caatinga. In: SIMPÓSIO REGIONAL DE GEOPROCESSAMENTO E SENSORIAMENTO REMOTO - GEONORDESTE, 6., 2012, Aracaju. Anais. Aracaju,SE: Embrapa Tabuleiros Costeiros, 2012. n.p.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Algodão. |
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| 16. | | FRANCISCO, P. R. M.; CHAVES, I. DE B.; CHAVES, L. H. G.; LIMA, E. R. V. DE; BRANDAO, Z. N.; SILVA, B. B. DA. Análise espectral e avaliação de índices de vegetação para o mapeamento da caatinga. A Mira, v. 22, n. 165, p. 61-64, 2013.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: Local - A |
| Biblioteca(s): Embrapa Algodão. |
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| 18. | | LIMA, J. L. S. de; CAVALCANTI, N. de B.; LIMA, E. R. de; CARVALHO, K. M. de; ORESOTU, B. A.; OLIVEIRA, C. A. V. Levantamento fitoecologico do municipio de Afranio- PE. In: CONGRESSO NACIONAL DE BOTANICA, 48., 1997, Crato. Resumos... Fortaleza: BNB, 1997. p. 230.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Semiárido. |
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| 19. | | LIMA, J. L. S. de; CAVALCANTI, N. de B.; LIMA, E. R. de; CARVALHO, K. M. de; ORESOTU, B. A.; OLIVEIRA, C. A. V. Levantamento fitoecologico do municipio de Ouricuri- PE. In: CONGRESSO NACIONAL DE BOTANICA, 48., 1997, Crato. Resumos... Fortaleza: BNB, 1997. p. 230| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Semiárido. |
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| 20. | | LOURENÇO, R. M.; LIMA, E. R. L. de; EID, J. G.; CORRÊA, O. A.; MOTA, S. A. P. da; MACHADO, N. T. Estudos relativos aos potenciais de determinadas oleaginosas para a produção de biocombustíveis. In: CONGRESSO BRASILEIRO DE MAMONA, 5.; SIMPÓSIO INTERNACIONAL DE OLEAGINOSAS ENERGÉTICAS, 2.; FÓRUM CAPIXABA DE PINHÃO-MANSO, 1., 2012, Guarapari. Desafios e Oportunidades: anais. Campina Grande: Embrapa Algodão, 2012. p. 6| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Algodão. |
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| Registros recuperados : 29 | |
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| Nenhum registro encontrado para a expressão de busca informada. |
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