Registro Completo |
Biblioteca(s): |
Ebooks. |
Data corrente: |
01/02/2013 |
Data da última atualização: |
01/02/2013 |
Autoria: |
WILSON, C. N.; MUSTAFA, S. J. |
Afiliação: |
Constance N. Wilson; S. Jamal Mustafa. |
Título: |
Adenosine Receptors in Health and Disease. |
Ano de publicação: |
2009 |
Fonte/Imprenta: |
Springer eBooks. |
Volume: |
193 |
Descrição Física: |
digital. |
Série: |
Handbook of Experimental Pharmacology, |
ISBN: |
9783540896159 |
DOI: |
10.1007/978-3-540-89615-9 |
Idioma: |
Inglês |
Conteúdo: |
Since their discovery approximately 25 years ago, adenosine receptors have now emerged as important novel molecular targets in disease and drug discovery. These proteins play important roles in the entire spectrum of disease from inflammation to immune suppression. Because of their expression on a number of different cell types and in a number of different organ systems they play important roles in specific diseases, including asthma, rheumatoid arthritis, Parkinson’s disease, multiple sclerosis, Alzheimer’s disease, heart disease, stroke, cancer, sepsis, and obesity. As a result of intense investigations into understanding the molecular structures and pharmacology of these proteins, new molecules have been synthesized that have high specificity for these proteins and are now entering clinical trials. These molecules will define the next new classes of drugs for a number of diseases with unmet medical needs. |
Palavras-Chave: |
Biomedicine; Cytology; Pharmacology/Toxicology. |
Thesaurus Nal: |
cell biology; human physiology; medicine; toxicology. |
Categoria do assunto: |
-- |
URL: |
https://dx.doi.org/10.1007/978-3-540-89615-9
|
Marc: |
LEADER 01636nam a2200253 a 4500 001 1947492 005 2013-02-01 008 2009 bl uuuu u0uu1 u #d 020 $a9783540896159 024 7 $a10.1007/978-3-540-89615-9$2DOI 100 1 $aWILSON, C. N. 245 $aAdenosine Receptors in Health and Disease.$h[electronic resource] 260 $aSpringer eBooks.$c2009 300 $a193$cdigital. 490 $aHandbook of Experimental Pharmacology,$v193 520 $a<P>Since their discovery approximately 25 years ago, adenosine receptors have now emerged as important novel molecular targets in disease and drug discovery. These proteins play important roles in the entire spectrum of disease from inflammation to immune suppression. Because of their expression on a number of different cell types and in a number of different organ systems they play important roles in specific diseases, including asthma, rheumatoid arthritis, Parkinson’s disease, multiple sclerosis, Alzheimer’s disease, heart disease, stroke, cancer, sepsis, and obesity. As a result of intense investigations into understanding the molecular structures and pharmacology of these proteins, new molecules have been synthesized that have high specificity for these proteins and are now entering clinical trials. These molecules will define the next new classes of drugs for a number of diseases with unmet medical needs. </P> 650 $acell biology 650 $ahuman physiology 650 $amedicine 650 $atoxicology 653 $aBiomedicine 653 $aCytology 653 $aPharmacology/Toxicology 700 1 $aMUSTAFA, S. J.
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Ebooks (Ebooks) |
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