|
|
Registro Completo |
Biblioteca(s): |
Embrapa Unidades Centrais. |
Data corrente: |
30/01/2017 |
Data da última atualização: |
29/12/2017 |
Autoria: |
WEISS, M.; ANZILIERO, D.; MARTINS, M.; WEIBLEN, R.; FLORES, E. F. |
Afiliação: |
MARCELO WEISS, UNOESC; DENIZ ANZILIERO, IMED; MATHIAS MARTINS, UFSM; RUDI WEIBLEN, UFSM; EDUARDO FRUTADO FLORES, UFSM. |
Título: |
Safety and immunogenicity of a glycoprotein E gene-deleted bovine herpesvirus 1 strain as a candidate vaccine strain. |
Ano de publicação: |
2016 |
Fonte/Imprenta: |
Pesquisa Veterinária Brasileira, Rio de Janeiro, v. 36, n. 11, p. 1067-1074, nov. 2016. |
Idioma: |
Inglês |
Conteúdo: |
A glycoprotein E-deleted Brazilian bovine herpesvirus 1 (BoHV-1gE?) was tested regarding to safety and immunogenicity. Intramuscular inoculation of young calves with a high virus dose did not result in clinical signs or virus shedding during acute infection or after dexamethasone administration. Calves vaccinated once IM (group I) or subcutaneously (group II) with live BoHV-1gE? or twice with inactivated virus plus aluminum hydroxide (group IV) or MontanideTM (group V) developed VN titers of 2 to 8 (GMT:2); 2 to 4 (GMT:1.65); 2 to 16 (GMT:2.45) and 2 to 128 (GMT:3.9), respectively. All BoHV-1gE? vaccinated calves remained negative in an anti-gE ELISA. Lastly, six young calves vaccinated with live BoHV-1gE? and subsequently challenged with a virulent BoHV-1 strain shed less virus and developed only mild and transient nasal signs comparing to unvaccinated calves. Thus, the recombinant BoHV-1gE? is safe and immunogenic for calves and allows for serological differentiation by a gE-ELISA test. |
Palavras-Chave: |
Differential vaccine; Marker vaccine; Vacina diferencial; Vacina marcada. |
Thesaurus Nal: |
Bovine herpesvirus 1; Cattle. |
Categoria do assunto: |
-- |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/154255/1/Safety-and-immunogenicity.pdf
|
Marc: |
LEADER 01761naa a2200241 a 4500 001 2062165 005 2017-12-29 008 2016 bl uuuu u00u1 u #d 100 1 $aWEISS, M. 245 $aSafety and immunogenicity of a glycoprotein E gene-deleted bovine herpesvirus 1 strain as a candidate vaccine strain.$h[electronic resource] 260 $c2016 520 $aA glycoprotein E-deleted Brazilian bovine herpesvirus 1 (BoHV-1gE?) was tested regarding to safety and immunogenicity. Intramuscular inoculation of young calves with a high virus dose did not result in clinical signs or virus shedding during acute infection or after dexamethasone administration. Calves vaccinated once IM (group I) or subcutaneously (group II) with live BoHV-1gE? or twice with inactivated virus plus aluminum hydroxide (group IV) or MontanideTM (group V) developed VN titers of 2 to 8 (GMT:2); 2 to 4 (GMT:1.65); 2 to 16 (GMT:2.45) and 2 to 128 (GMT:3.9), respectively. All BoHV-1gE? vaccinated calves remained negative in an anti-gE ELISA. Lastly, six young calves vaccinated with live BoHV-1gE? and subsequently challenged with a virulent BoHV-1 strain shed less virus and developed only mild and transient nasal signs comparing to unvaccinated calves. Thus, the recombinant BoHV-1gE? is safe and immunogenic for calves and allows for serological differentiation by a gE-ELISA test. 650 $aBovine herpesvirus 1 650 $aCattle 653 $aDifferential vaccine 653 $aMarker vaccine 653 $aVacina diferencial 653 $aVacina marcada 700 1 $aANZILIERO, D. 700 1 $aMARTINS, M. 700 1 $aWEIBLEN, R. 700 1 $aFLORES, E. F. 773 $tPesquisa Veterinária Brasileira, Rio de Janeiro$gv. 36, n. 11, p. 1067-1074, nov. 2016.
Download
Esconder MarcMostrar Marc Completo |
Registro original: |
Embrapa Unidades Centrais (AI-SEDE) |
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
Registros recuperados : 26 | |
13. | | SILVA, J. G. da; SARMENTO, P. H. L.; NASCENTE, A. S.; GONZAGA, A. C. O. Desempenho de ceifadoras, recolhedoras trilhadoras e colhedoras automotrizes na colheita do feijão-comum na região do cerrado. In: CONGRESSO NACIONAL DE PESQUISA DE FEIJÃO, 13., 2021, Goiânia. Conectividade tecnológica, intensificação sustentável: resumos. Brasília, DF: Embrapa; Santo Antônio de Goiás: Embrapa Arroz e Feijão, 2021. p. 243. Evento online.Tipo: Resumo em Anais de Congresso |
Biblioteca(s): Embrapa Arroz e Feijão. |
| |
14. | | SARMENTO, P. H. L.; NORONHA JÚNIOR, N. C. de; OLIVEIRA, L. F. C. de. Rentabilidade dos sistemas de produção. In: ALTMANN, N.; LOBO JUNIOR, M.; NUNES, R. de S.; TORMEN, N. R.; SARMENTO, P. H. L. (ed.). Vida no solo. Brasília, DF: GTEC Brasil Central, 2023. Capítulo 8, p. 132-140. il.Tipo: Capítulo em Livro Técnico-Científico |
Biblioteca(s): Embrapa Arroz e Feijão. |
| |
Registros recuperados : 26 | |
|
Nenhum registro encontrado para a expressão de busca informada. |
|
|