Data/hora: 05/06/2024 13:00:00

Biblioteca(s): 	Embrapa Unidades Centrais.	
Data corrente: 	02/04/2018	
Data da última atualização: 	02/04/2018	
Autoria: 	ZHU, H.; ZHANG, H.; WANG, Y.; CIREN, D.; DONG, H.; WU, Q.; REHMAN, M. U.; NABI, F.; MEHMOOD, K.; LI, J.	
Afiliação: 	Hongyun Zhu, Key Laboratory of Clinical Veterinary Medicine in Tibet/XiZang Agriculture and Animal Husbandry College; Hui Zhang, College of Veterinary Medicine/Huazhong Agricultural University; Yajing Wang, College of Veterinary Medicine/Huazhong Agricultural University; Danba Ciren, Key Laboratory of Clinical Veterinary Medicine in Tibet/XiZang Agriculture and Animal Husbandry College; Hailong Dong, Key Laboratory of Clinical Veterinary Medicine in Tibet/XiZang Agriculture and Animal Husbandry College; Qingxia Wu, College of Veterinary Medicine/Huazhong Agricultural University; Mujeeb Ur Rehman, College of Veterinary Medicine/Huazhong Agricultural University; Fazul Nabi, College of Veterinary Medicine/Huazhong Agricultural University; Khalid Mehmood, College of Veterinary Medicine/Huazhong Agricultural University,University College of Veterinary and Animal Sciences, Islamia University of Bahawalpur; Jiakui Li, Key Laboratory of Clinical Veterinary Medicine in Tibet/XiZang Agriculture and Animal Husbandry College.	
Título: 	Phylogenetic and pathotypic characterization of newcastle disease virus in Tibetan chickens, China.	
Ano de publicação: 	2018	
Fonte/Imprenta: 	Pesquisa Veterinária Brasileira, Rio de Janeiro, v. 38, n. 1, p. 37-40, janeiro 2018.	
Idioma: 	Inglês	
Conteúdo: 	Chickens are considered to be potential reservoirs of Newcastle disease virus (NDV). In this study, six Newcastle disease virus strains were isolated and characterized in Tibetan chickens. The HN gene was sequenced, and phylogenetic relationship to reference strains was studied. The phylogenetic analysis demonstrated that these six isolated strains were closely related to NDV isolates of the reference strains GQ245823, KT002186, KU527561, J563939, AY225110, EU305607, KM056357, Y18898, GQ245832, AF077761 and lasota strain. Among them, EU305607, KJ563939 and KM056357 were isolated from India, while lasota strain came from attenuated vaccine widely used in China. Then, mean death time (MDT) and intracerebral pathogenicity index (ICPI) were used to estimate the pathogenicity of the isolates. Pathogenicity experiment showed HNH1 and HN17 to be virulent. Our results indicated that genetically diverse viruses circulate in Tibetan chickens, and based upon the phlogeographic analysis, we estimated the origin of ancestral viruses of the isolates and its sister strains located in India and China (lasota strain). It indicates the importance of continuous surveillance to enhance current understanding of the genetic evolution of the NDV strains.	
Palavras-Chave: 	Tibetan chickens.	
Thesaurus Nal: 	Newcastle disease virus; Pathogenicity; Phylogeny.	
Categoria do assunto: 	--	
URL: 	http://ainfo.cnptia.embrapa.br/digital/bitstream/item/174793/1/Phylogenetic-and-pathojtypic-characterization-of-newcastle.pdf	
Registro original: 	Embrapa Unidades Centrais (AI-SEDE)	
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