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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
06/07/2017 |
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Data da última atualização: |
06/07/2017 |
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Autoria: |
RADIX, P. M. WALTERS, C. S. ADKINS, J. A. |
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Título: |
The influence of ethionine-supplemented soy protein diet on cell-mediated and humoral immunity. |
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Ano de publicação: |
1983 |
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Fonte/Imprenta: |
The Journal of Nutrition, v. 113, n. 1, p. 159-164, Jan. 1983. |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: These studies were designed to investigate the influence of ethionine, a suspected carcinogen, on cell-mediated (CMI) and humoral immunity. It is believed that ethionine, an analog of methionine which is produced by intestinal bacteria, could have significant relevance to health. To study the effect of ethionine on immune responsiveness, three groups of mice were allowed to feed ad libitum for 5 weeks on one of the following regimens: diet 1, a basal diet of 16% soy protein; diet 2, soy protein supplemented with 0.6% dl-methionine; and diet 3, soy protein supplemented with 0.1% dl-ethionine. The immunological parameters measured were responsiveness to mitogens, [phytohemagglutinin (PHA), concanavalin A (Con A), pokeweed mitogen (PWM), and lipopolysaccharide (LPS)], delayed-type hypersensitivity (DTH) to dinitrofluorobenzene (DNFB), and antibody formation to sheep red blood cells (SRBC). There were no significant differences in mitogen and antigen responses in mice maintained on diets 1 and 2 as measured by thymidine uptake in proliferating lymphocytes. However, there was a significant suppression in mitogen responsiveness in mice that received diet 3. DTH was also suppressed in mice on diet 3. Antibody levels were similar in all groups. Thus, there was clear evidence of suppression of CMI by ethionine in these studies. |
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Palavras-Chave: |
Dinitrofluorobenzene; Dosage effects; Drug effects; Mitogens; Protein requirements; Supplementary feeding. |
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Thesaurus Nal: |
Ethionine; Hypersensitivity; Immunology; Lipopolysaccharides; Mice; Pharmacology; Sheep; Soybeans. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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Marc: |
LEADER 02175naa a2200289 a 4500
001 2072025
005 2017-07-06
008 1983 bl uuuu u00u1 u #d
100 1 $aRADIX, P. M. WALTERS, C. S. ADKINS, J. A.
245 $aThe influence of ethionine-supplemented soy protein diet on cell-mediated and humoral immunity.
260 $c1983
520 $aAbstract: These studies were designed to investigate the influence of ethionine, a suspected carcinogen, on cell-mediated (CMI) and humoral immunity. It is believed that ethionine, an analog of methionine which is produced by intestinal bacteria, could have significant relevance to health. To study the effect of ethionine on immune responsiveness, three groups of mice were allowed to feed ad libitum for 5 weeks on one of the following regimens: diet 1, a basal diet of 16% soy protein; diet 2, soy protein supplemented with 0.6% dl-methionine; and diet 3, soy protein supplemented with 0.1% dl-ethionine. The immunological parameters measured were responsiveness to mitogens, [phytohemagglutinin (PHA), concanavalin A (Con A), pokeweed mitogen (PWM), and lipopolysaccharide (LPS)], delayed-type hypersensitivity (DTH) to dinitrofluorobenzene (DNFB), and antibody formation to sheep red blood cells (SRBC). There were no significant differences in mitogen and antigen responses in mice maintained on diets 1 and 2 as measured by thymidine uptake in proliferating lymphocytes. However, there was a significant suppression in mitogen responsiveness in mice that received diet 3. DTH was also suppressed in mice on diet 3. Antibody levels were similar in all groups. Thus, there was clear evidence of suppression of CMI by ethionine in these studies.
650 $aEthionine
650 $aHypersensitivity
650 $aImmunology
650 $aLipopolysaccharides
650 $aMice
650 $aPharmacology
650 $aSheep
650 $aSoybeans
653 $aDinitrofluorobenzene
653 $aDosage effects
653 $aDrug effects
653 $aMitogens
653 $aProtein requirements
653 $aSupplementary feeding
773 $tThe Journal of Nutrition$gv. 113, n. 1, p. 159-164, Jan. 1983.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
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| Registros recuperados : 11 | |
| 6. |  | EIRA, M. T. S.; RIBEIRO, V. S.; FAZUOLI, L. C.; GUERREIRO FILHO, O.; WALTERS, C. Coffee seed cryopreservation: current research progress. In: INTERNATIONAL CONFERENCE ON COFFEE SCIENCE, 21., 2006, Montpellier, France. Table of contents... Montpellier, France: Association for Science and Information on Coffee, 2006.| Tipo: Artigo em Anais de Congresso / Nota Técnica |
| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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| 7. | | EIRA, M. T. S. da; RIBEIRO, V. S.; FUZUOLI, L. C.; GUERREIRO FILHO, O.; WALTERS, C. Coffee seed cryopreservation: current research progress. In:INTERNATIONAL CONFERENCE ON COFFEE SCIENCE, 21., 2006, Montpellier, France. Table of contents... Montpellier, France: Association for Science and Information on Coffee, 2007. 1 CD-ROM.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Café. |
|  |
| 10. | | EIRA, M. T. S.; WALTERS, C.; CALDAS, L. S.; FAZUOLI, L. C.; SAMPAIO, J. B.; DIAS, M. C. L. L. Tolerance of coffea spp. seeds to desiccation and low temperature. Revista Brasileira de Fisiologia Vegetal, Brasília, v. 11, n. 2, p. 97-105, 1999.| Biblioteca(s): Embrapa Cerrados. |
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| 11. | | EIRA, M. T. S.; SILVA, E. A. A. da; CASTRO, R. D. de; DUSSERT, S.; WALTERS, C.; BEWLEY, J. D.; HILHORST, H. W. M. Coffee seed physiology. Brazilian Journal of Plant Physiology, v. 18, n. 1, p. 149-163, 2006.| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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| Registros recuperados : 11 | |
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