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Registro Completo |
Biblioteca(s): |
Embrapa Agroindústria Tropical; Embrapa Pecuária Sudeste; Embrapa Pecuária Sul. |
Data corrente: |
09/05/2019 |
Data da última atualização: |
17/02/2020 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
SOARES, S. M.; DOMINGUES, R.; GASPAR, E. B.; SANTOS, P. A. dos; CANUTO, K. M.; MINHO, A. P.; VIEIRA, M. I. B. |
Afiliação: |
SUELEN MENDONÇA SOARES, UPF; ROBERT DOMINGUES, CPPSUL; EMANUELLE BALDO GASPAR, CPPSUL; PATRÍCIO AZEVEDO DOS SANTOS, URCAMP; KIRLEY MARQUES CANUTO, CNPAT; ALESSANDRO PELEGRINE MINHO, CPPSE; MARIA ISABEL BOTELHO VIEIRA, UPF. |
Título: |
In vitro ovicidal effect of a Senecio brasiliensis extract and its fractions on Haemonchus contortus. |
Ano de publicação: |
2019 |
Fonte/Imprenta: |
BMC Veterinary Research, v. 15, n. 99, 25 Mar. 2019. |
Páginas: |
9 p. |
DOI: |
10.1186/s12917-019-1843-7 |
Idioma: |
Inglês |
Conteúdo: |
Background: Haemonchosis affects sheep husbandry and its treatment is often compromised due to the development of anthelminthic resistance. Plant-derived bioactive compounds have been studied as alternative to control Haemonchus contortus. The objective of this study was to evaluate the effect of Senecio brasiliensis extracts on H. contortus egg hatching and infective larvae migration. Results: The aqueous extract from dried and fresh plant and alkaloid-enriched fraction of the previously dried leaves of S. brasiliensis inhibited H. contortus egg hatching. The main plant compound in alkaloid fraction was integerrimine, a pyrrolizidine alkaloid (PA). However, the aqueous extract from dried plant displayed higher efficacy when compared to their alkaloid enriched or non-polar fractions, meaning that, although PAs contributed to the ovicidal effect, other compounds in the plant can also contribute to their effect. Furthermore, the aqueous extract from dried plant also had higher efficacy than aqueous extract from fresh plant in larvae migration inhibition. Finally, extract from dried plant presented low in vitro cytotoxic effect. Conclusion: Taken together our results suggest a good anthelmintic effect of S. brasiliensis, especially when aqueous extract is prepared from dried plant. Further in vivo studies should be performed focused on forms of administration of this extract in rearing sheep. |
Palavras-Chave: |
Alcalóides de pirrolizidina; Antelmíntico; Egg hatching; Incubação de ovos; Infective larvae migration; Migração de larvas infectantes; Pequenos ruminantes. |
Thesagro: |
Anti-Helmíntico; Extrato Vegetal; Incubação Artificial; Maria Mole; Nematóide; Planta Tóxica. |
Thesaurus Nal: |
Plant extracts; Pyrrolizidine alkaloids; Small ruminants. |
Categoria do assunto: |
-- |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/197181/1/In-vitro-ovicidal-effect-Senecio.pdf
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/208998/1/ART19126.pdf
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Marc: |
LEADER 02626naa a2200409 a 4500 001 2108906 005 2020-02-17 008 2019 bl uuuu u00u1 u #d 024 7 $a10.1186/s12917-019-1843-7$2DOI 100 1 $aSOARES, S. M. 245 $aIn vitro ovicidal effect of a Senecio brasiliensis extract and its fractions on Haemonchus contortus.$h[electronic resource] 260 $c2019 300 $a9 p. 520 $aBackground: Haemonchosis affects sheep husbandry and its treatment is often compromised due to the development of anthelminthic resistance. Plant-derived bioactive compounds have been studied as alternative to control Haemonchus contortus. The objective of this study was to evaluate the effect of Senecio brasiliensis extracts on H. contortus egg hatching and infective larvae migration. Results: The aqueous extract from dried and fresh plant and alkaloid-enriched fraction of the previously dried leaves of S. brasiliensis inhibited H. contortus egg hatching. The main plant compound in alkaloid fraction was integerrimine, a pyrrolizidine alkaloid (PA). However, the aqueous extract from dried plant displayed higher efficacy when compared to their alkaloid enriched or non-polar fractions, meaning that, although PAs contributed to the ovicidal effect, other compounds in the plant can also contribute to their effect. Furthermore, the aqueous extract from dried plant also had higher efficacy than aqueous extract from fresh plant in larvae migration inhibition. Finally, extract from dried plant presented low in vitro cytotoxic effect. Conclusion: Taken together our results suggest a good anthelmintic effect of S. brasiliensis, especially when aqueous extract is prepared from dried plant. Further in vivo studies should be performed focused on forms of administration of this extract in rearing sheep. 650 $aPlant extracts 650 $aPyrrolizidine alkaloids 650 $aSmall ruminants 650 $aAnti-Helmíntico 650 $aExtrato Vegetal 650 $aIncubação Artificial 650 $aMaria Mole 650 $aNematóide 650 $aPlanta Tóxica 653 $aAlcalóides de pirrolizidina 653 $aAntelmíntico 653 $aEgg hatching 653 $aIncubação de ovos 653 $aInfective larvae migration 653 $aMigração de larvas infectantes 653 $aPequenos ruminantes 700 1 $aDOMINGUES, R. 700 1 $aGASPAR, E. B. 700 1 $aSANTOS, P. A. dos 700 1 $aCANUTO, K. M. 700 1 $aMINHO, A. P. 700 1 $aVIEIRA, M. I. B. 773 $tBMC Veterinary Research$gv. 15, n. 99, 25 Mar. 2019.
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Registro original: |
Embrapa Pecuária Sul (CPPSUL) |
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Registros recuperados : 6 | |
1. | | SOARES, S. M.; GASPAR, E. B.; SUÑÉ, R. W.; VIEIRA, M. I. B.; MINHO, A. P. Correlação entre testes laboratoriais e a campo para detecção de mastite subclínica em rebanhos leiteiros. Anais do Salão Internacional de Ensino, Pesquisa e Extensão, Bagé, v. 8, n. 4, 2016.Tipo: Artigo em Anais de Congresso |
Biblioteca(s): Embrapa Pecuária Sul. |
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3. | | VIEIRA, M. I. B.; LEITE, R. C.; MARTINS, J. R.; SACCO, A. M. S.; SILVA, J. G. C. Resposta imune humoral contra Anaplasma marginale (Theiler, 1910) em bovinos submetidos a distintas estratégias de controle do carrapato vetor Boophilus microplus (Canestrini, 1887). Revista Brasileira de Parasitologia Veterinária, v. 11, n. 2, p. 71-76, 2002.Tipo: Artigo em Periódico Indexado | Circulação/Nível: Nacional - A |
Biblioteca(s): Embrapa Pecuária Sul. |
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4. | | SOARES, S. M.; DOMINGUES, R.; GASPAR, E. B.; SANTOS, P. A. dos; CANUTO, K. M.; MINHO, A. P.; VIEIRA, M. I. B. In vitro ovicidal effect of a Senecio brasiliensis extract and its fractions on Haemonchus contortus. BMC Veterinary Research, v. 15, n. 99, 25 Mar. 2019. 9 p.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Agroindústria Tropical; Embrapa Pecuária Sudeste; Embrapa Pecuária Sul. |
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5. | | ROSÉS, T. de S.; ANDREOLLA, A. P.; SOVERAL, L. de F.; VIEIRA, M. I. B.; KICH, J. D.; FRANDALOSO, R.; KREUTZ, L. C. Synthetic gene as target to assess the sensitivity of PCR to detect Trichinella spp. larvae in meat from a non-endemic region. Tropical Animal Health and Production, v. 52, n. 2, p. 619-623, Mar. 2020.Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 1 |
Biblioteca(s): Embrapa Suínos e Aves. |
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6. | | LIMA, E. S. de; ROCHA, C. S.; RITTERBUSCH, G. A.; MORES, N.; AMARAL, A. L. do; VENTURA, L.; DAMBRÓS, R. M.; KUCHIISHI, S. S.; VIEIRA, M. I. B.; ZANELLA, J. R. C. Differential serological screening of reproductive infectious agents important for surveillance. In: INTERNATIONAL PIG VETERINARY SOCIETY(IPVS) CONGRESS, 21., 2010, Vancouver. Proceedings... Vancouver: IPVS, 2010. p. 1122. 1 CD-Rom. Projeto/Plano de Ação: 1600.30.004.Tipo: Artigo em Anais de Congresso |
Biblioteca(s): Embrapa Suínos e Aves. |
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Registros recuperados : 6 | |
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