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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
01/04/2005 |
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Data da última atualização: |
01/04/2005 |
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Autoria: |
MARSHALL, K.; HENSHALL, J.; VAN DER WERF, J. H. J. |
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Título: |
Response from marker-assisted selection when various proportions of animals are marker typed: a multiple trait simulation study relevant to the sheepmeat industry. |
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Ano de publicação: |
2002 |
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Fonte/Imprenta: |
Animal Science, v. 74, pt 2, p. 223-232, 2002. |
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Idioma: |
Inglês |
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Conteúdo: |
A simulation study, based on a closed sheepmeat breeding nucleus and incorporating marker-assisted selection (MAS), was used to evaluate response when different proportions of animaIs were marker typed. Two traits were included in the simulation: trait 1, a production trait where phenotypes were available prior to selection, and trait 2, a carcass trait where phenotypic information was not available on breeding animaIs. Selection on an index which comprised estimated breeding values (EBVs) for both traits was possible by calculating EBVs for trait 2 as the sum of EBVs for a polygenic component, obtained from a genetic regression, and EBVs for a major gene component, obtained by inferring genotypes at a major gene locus from a linked marker locus. Different marker typing strategies were evaluated. These differed in the criteria tlsed to select progeny for typing, and in the proportion of male and female progeny selected. Typing progeny that were likely to be used as a breeding animal, but excluding those whose marker genotype could be predicted with reasonable certainty, was an efficient genotyping strategy. Close to maximum gain at the major gene locus was achieved when only a proportion of animaIs were marker typed (for example 90% of maximum response was achieved with a little over one-third of the selection candidates marker typed), This indicates the potential for substantial savings in relation to the cosi of marker typing in commercial breeding flocks. |
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Palavras-Chave: |
Genética quantitativa; Melhoramento genético; QTLs. |
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Thesagro: |
Carne; Genética Animal; Ovino; Seleção Genética. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02194naa a2200229 a 4500
001 1531058
005 2005-04-01
008 2002 bl uuuu u00u1 u #d
100 1 $aMARSHALL, K.
245 $aResponse from marker-assisted selection when various proportions of animals are marker typed$ba multiple trait simulation study relevant to the sheepmeat industry.
260 $c2002
520 $aA simulation study, based on a closed sheepmeat breeding nucleus and incorporating marker-assisted selection (MAS), was used to evaluate response when different proportions of animaIs were marker typed. Two traits were included in the simulation: trait 1, a production trait where phenotypes were available prior to selection, and trait 2, a carcass trait where phenotypic information was not available on breeding animaIs. Selection on an index which comprised estimated breeding values (EBVs) for both traits was possible by calculating EBVs for trait 2 as the sum of EBVs for a polygenic component, obtained from a genetic regression, and EBVs for a major gene component, obtained by inferring genotypes at a major gene locus from a linked marker locus. Different marker typing strategies were evaluated. These differed in the criteria tlsed to select progeny for typing, and in the proportion of male and female progeny selected. Typing progeny that were likely to be used as a breeding animal, but excluding those whose marker genotype could be predicted with reasonable certainty, was an efficient genotyping strategy. Close to maximum gain at the major gene locus was achieved when only a proportion of animaIs were marker typed (for example 90% of maximum response was achieved with a little over one-third of the selection candidates marker typed), This indicates the potential for substantial savings in relation to the cosi of marker typing in commercial breeding flocks.
650 $aCarne
650 $aGenética Animal
650 $aOvino
650 $aSeleção Genética
653 $aGenética quantitativa
653 $aMelhoramento genético
653 $aQTLs
700 1 $aHENSHALL, J.
700 1 $aVAN DER WERF, J. H. J.
773 $tAnimal Science$gv. 74, pt 2, p. 223-232, 2002.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
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