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Registro Completo |
Biblioteca(s): |
Embrapa Gado de Corte. |
Data corrente: |
01/06/1993 |
Data da última atualização: |
15/10/2007 |
Autoria: |
VALLE, C. B. do. |
Afiliação: |
EMBRAPA. Centro Nacional de Pesquisa de Gado de Corte (Campo Grande, MS). |
Título: |
A busca de novas forrageiras: as pastagens do futuro - I. |
Ano de publicação: |
1993 |
Fonte/Imprenta: |
In : CURSO de pastagens para sementeiros, 1993, Campo Grande, MS. Campo Grande, MS: EMBRAPA, CNPGC, 1993. |
Páginas: |
p. 48-54. |
Idioma: |
Português |
Notas: |
CNPGC. |
Palavras-Chave: |
EMBRAPA-CNPGC; Forrageira; Melhoramento genetico. |
Thesagro: |
Brachiaria; Centrosema; Panicum Maximum; Pastagem; Seleção. |
Thesaurus Nal: |
Calopogonium; Paspalum. |
Categoria do assunto: |
-- |
Marc: |
LEADER 00706naa a2200253 a 4500 001 1321523 005 2007-10-15 008 1993 bl uuuu u00u1 u #d 100 1 $aVALLE, C. B. do 245 $aA busca de novas forrageiras$bas pastagens do futuro - I. 260 $c1993 300 $ap. 48-54. 500 $aCNPGC. 650 $aCalopogonium 650 $aPaspalum 650 $aBrachiaria 650 $aCentrosema 650 $aPanicum Maximum 650 $aPastagem 650 $aSeleção 653 $aEMBRAPA-CNPGC 653 $aForrageira 653 $aMelhoramento genetico 773 $tIn : CURSO de pastagens para sementeiros, 1993, Campo Grande, MS. Campo Grande, MS: EMBRAPA, CNPGC, 1993.
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Registro original: |
Embrapa Gado de Corte (CNPGC) |
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Registro Completo
Biblioteca(s): |
Embrapa Pecuária Sudeste. |
Data corrente: |
04/09/2019 |
Data da última atualização: |
09/01/2020 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
B - 1 |
Autoria: |
SANTOS, R. M. dos; FERNANDO, F. S.; MONTASSIER, M. de F. S.; SILVA, K. R.; LOEPS, P. D.; PAVANI, C.; BORZI, M. M.; OKINO, C. H.; MONTASSIER, H. J. |
Afiliação: |
Romeu Moreira dos Santos, UNESP; Filipe Santos Fernando, UNESP; Maria de Fátima Silva Montassier, UNESP; Ketherson Rodrigues Silva, UNESP; Priscila Diniz Lopes, UNESP; Caren Pavani, UNESP; Mariana Monezi Borzi, UNESP; CINTIA HIROMI OKINO, CPPSE; Helio José Montassier, UNESP. |
Título: |
Memory immune responses and protection of chickens against a nephropathogenic infectious bronchitis virus strain by combining live heterologous and inactivated homologous vaccines. |
Ano de publicação: |
2019 |
Fonte/Imprenta: |
The Journal of Veterinary Medical Science, v.81, n.4, p.612-619, 2019. |
DOI: |
10.1292/jvms.18-0065 |
Idioma: |
Inglês |
Conteúdo: |
In this study, we evaluated antibody and cell-mediated immune (CMI) responses in the mucosal and systemic compartments and protection against challenge with a nephropathogenic Brazilian (BR-I) strain of infectious bronchitis virus (IBV) in chickens submitted to a vaccination regime comprising a priming dose of heterologous live attenuated Massachusetts vaccine followed by a booster dose of an experimental homologous inactivated vaccine two weeks later. This immunization protocol elicited significant increases in serum and lachrymal levels of anti-IBV IgG antibodies and upregulated the expression of CMI response genes, such as those encoding CD8? chain and Granzyme homolog A in tracheal and kidney tissues at 3, 7, and 11 days post-infection in the vaccinated chickens. Additionally, vaccinated and challenged chickens showed reduced viral loads and microscopic lesion counts in tracheal and kidney tissues, and their antibody and CMI responses were negatively correlated with viral loads in the trachea and kidney. In conclusion, the combination of live attenuated vaccine containing the Massachusetts strain with a booster dose of an inactivated vaccine, containing a BR-I IBV strain, confers effective protection against infection with nephropathogenic homologous IBV strain because of the induction of consistent memory immune responses mediated by IgG antibodies and TCD8 cells in the mucosal and systemic compartments of chickens submitted to this vaccination regime. |
Palavras-Chave: |
Cell mediated immunity; Oil adjuvant. |
Thesaurus NAL: |
Avian coronavirus; Humoral immunity; Mucosal immunity. |
Categoria do assunto: |
X Pesquisa, Tecnologia e Engenharia |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/201566/1/Memory-Immune-Responses.pdf
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Marc: |
LEADER 02441naa a2200289 a 4500 001 2111878 005 2020-01-09 008 2019 bl uuuu u00u1 u #d 024 7 $a10.1292/jvms.18-0065$2DOI 100 1 $aSANTOS, R. M. dos 245 $aMemory immune responses and protection of chickens against a nephropathogenic infectious bronchitis virus strain by combining live heterologous and inactivated homologous vaccines.$h[electronic resource] 260 $c2019 520 $aIn this study, we evaluated antibody and cell-mediated immune (CMI) responses in the mucosal and systemic compartments and protection against challenge with a nephropathogenic Brazilian (BR-I) strain of infectious bronchitis virus (IBV) in chickens submitted to a vaccination regime comprising a priming dose of heterologous live attenuated Massachusetts vaccine followed by a booster dose of an experimental homologous inactivated vaccine two weeks later. This immunization protocol elicited significant increases in serum and lachrymal levels of anti-IBV IgG antibodies and upregulated the expression of CMI response genes, such as those encoding CD8? chain and Granzyme homolog A in tracheal and kidney tissues at 3, 7, and 11 days post-infection in the vaccinated chickens. Additionally, vaccinated and challenged chickens showed reduced viral loads and microscopic lesion counts in tracheal and kidney tissues, and their antibody and CMI responses were negatively correlated with viral loads in the trachea and kidney. In conclusion, the combination of live attenuated vaccine containing the Massachusetts strain with a booster dose of an inactivated vaccine, containing a BR-I IBV strain, confers effective protection against infection with nephropathogenic homologous IBV strain because of the induction of consistent memory immune responses mediated by IgG antibodies and TCD8 cells in the mucosal and systemic compartments of chickens submitted to this vaccination regime. 650 $aAvian coronavirus 650 $aHumoral immunity 650 $aMucosal immunity 653 $aCell mediated immunity 653 $aOil adjuvant 700 1 $aFERNANDO, F. S. 700 1 $aMONTASSIER, M. de F. S. 700 1 $aSILVA, K. R. 700 1 $aLOEPS, P. D. 700 1 $aPAVANI, C. 700 1 $aBORZI, M. M. 700 1 $aOKINO, C. H. 700 1 $aMONTASSIER, H. J. 773 $tThe Journal of Veterinary Medical Science$gv.81, n.4, p.612-619, 2019.
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Embrapa Pecuária Sudeste (CPPSE) |
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