| |
|
|
 | Acesso ao texto completo restrito à biblioteca da Embrapa Pecuária Sudeste. Para informações adicionais entre em contato com cppse.biblioteca@embrapa.br. |
|
Registro Completo |
|
Biblioteca(s): |
Embrapa Pecuária Sudeste. |
|
Data corrente: |
16/11/2020 |
|
Data da última atualização: |
10/08/2022 |
|
Tipo da produção científica: |
Artigo em Periódico Indexado |
|
Autoria: |
TOSCANO, J. H. B.; OKINO, C. H.; SANTOS, I. B. dos; GIRALDELO, L. A.; HAEHLING, M. B. von; ESTEVES, S. N.; BASSETTO, C. C.; AMARANTE, A. F. T. do; CHAGAS, A. C. de S. |
|
Afiliação: |
João Henrique Barbosa Toscano, UNESP; CINTIA HIROMI OKINO, CPPSE; Isabella Barbosa dos Santos, UNESP; Luciana Aparecida Giraldelo, UNICEP; Marei Borsch von Haehling, UNESP; SERGIO NOVITA ESTEVES, CPPSE; Cesar Cristiano Bassetto, UNESP; Alessandro Francisco Talamini do Amarante, UNESP; ANA CAROLINA DE SOUZA CHAGAS, CPPSE. |
|
Título: |
Local and systemic immune mediators of Morada Nova lambs with divergent Haemonchus contortus resistance phenotypes. |
|
Ano de publicação: |
2020 |
|
Fonte/Imprenta: |
Parasite Immunology, v. 42, e12790, 2020. |
|
Páginas: |
10 p. |
|
DOI: |
https://doi.org/10.1111/pim.12790 |
|
Idioma: |
Inglês |
|
Conteúdo: |
Aims: Local and systemic immune mediators of Morada Nova lambs with divergent Haemonchus contortus resistance phenotypes were evaluated. Methods and Results: Lambs were ranked through faecal egg counts (FEC) after two parasitic challenges with 4,000 H.contortus L3. After the second challenge, the lambs underwent a third artificial infection and were euthanized 7 days later. Immunerelated genes were quantified locally in abomasal mucosa and lymph nodes (CD4, IFN?, IL4, IL5, IL13, IL2RA and MS4A2) and systemically in the whole blood (IL4 and IL13). Anti-H. contortus IgG and IgA antibodies and eosinophils and mast cells counts were also investigated. Resistant animals presented higher systemic IgG and IgA titres, both negatively correlated with FEC. Susceptible animals had higher blood levels of IL4 transcripts. At the local level, resistant lambs had higher eosinophils counts and superior MS4A2 levels in abomasal fundic mucosa, besides higher IgA levels in abomasal mucus, while susceptible lamb had superior IL4 expression in abomasal lymph nodes. Conclusion: These data indicate that resistant lambs had an immune response mediated by antibody-mediated cytotoxicity. Also, the systemic humoral profile, particularly IgA isotype, seems to be a good resistance marker for Morada Nova sheep, as we found differences between groups even when FEC did not differ. |
|
Palavras-Chave: |
Host resistance; Morada Nova. |
|
Thesagro: |
Elisa; Haemonchus Contortus. |
|
Thesaurus Nal: |
Eosinophils; Gene expression; Sheep breeds. |
|
Categoria do assunto: |
H Saúde e Patologia |
|
Marc: |
LEADER 02332naa a2200325 a 4500
001 2126621
005 2022-08-10
008 2020 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1111/pim.12790$2DOI
100 1 $aTOSCANO, J. H. B.
245 $aLocal and systemic immune mediators of Morada Nova lambs with divergent Haemonchus contortus resistance phenotypes.$h[electronic resource]
260 $c2020
300 $a10 p.
520 $aAims: Local and systemic immune mediators of Morada Nova lambs with divergent Haemonchus contortus resistance phenotypes were evaluated. Methods and Results: Lambs were ranked through faecal egg counts (FEC) after two parasitic challenges with 4,000 H.contortus L3. After the second challenge, the lambs underwent a third artificial infection and were euthanized 7 days later. Immunerelated genes were quantified locally in abomasal mucosa and lymph nodes (CD4, IFN?, IL4, IL5, IL13, IL2RA and MS4A2) and systemically in the whole blood (IL4 and IL13). Anti-H. contortus IgG and IgA antibodies and eosinophils and mast cells counts were also investigated. Resistant animals presented higher systemic IgG and IgA titres, both negatively correlated with FEC. Susceptible animals had higher blood levels of IL4 transcripts. At the local level, resistant lambs had higher eosinophils counts and superior MS4A2 levels in abomasal fundic mucosa, besides higher IgA levels in abomasal mucus, while susceptible lamb had superior IL4 expression in abomasal lymph nodes. Conclusion: These data indicate that resistant lambs had an immune response mediated by antibody-mediated cytotoxicity. Also, the systemic humoral profile, particularly IgA isotype, seems to be a good resistance marker for Morada Nova sheep, as we found differences between groups even when FEC did not differ.
650 $aEosinophils
650 $aGene expression
650 $aSheep breeds
650 $aElisa
650 $aHaemonchus Contortus
653 $aHost resistance
653 $aMorada Nova
700 1 $aOKINO, C. H.
700 1 $aSANTOS, I. B. dos
700 1 $aGIRALDELO, L. A.
700 1 $aHAEHLING, M. B. von
700 1 $aESTEVES, S. N.
700 1 $aBASSETTO, C. C.
700 1 $aAMARANTE, A. F. T. do
700 1 $aCHAGAS, A. C. de S.
773 $tParasite Immunology$gv. 42, e12790, 2020.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Pecuária Sudeste (CPPSE) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
|
| Acesso ao texto completo restrito à biblioteca da Embrapa Recursos Genéticos e Biotecnologia. Para informações adicionais entre em contato com cenargen.biblioteca@embrapa.br. |
Registro Completo
|
Biblioteca(s): |
Embrapa Recursos Genéticos e Biotecnologia. |
|
Data corrente: |
02/08/2023 |
|
Data da última atualização: |
07/11/2023 |
|
Tipo da produção científica: |
Artigo em Periódico Indexado |
|
Circulação/Nível: |
A - 1 |
|
Autoria: |
SREEDASYAM, A.; PLOTT, C.; HOSSAIN, M. S.; LOVELL, J. T.; GRIMWOOD, J.; JENKINS, J. W.; DAUM, C.; BARRY, K.; CARLSON, J.; SHU, S.; PHILLIPS, J.; AMIREBRAHIMI, M.; ZANE, M.; WANG, M.; GOODSTEIN, D.; HAAS, F. B.; HISS, M.; PERROUD, P.-F.; JAWDY, S. S.; YANG, Y.; HU, R.; JOHNSON, J.; KROPAT, J.; GALLAHER, S. D.; LIPZEN, A.; SHAKIROV, E. V.; WENG, X.; TORRES-JEREZ, I.; WEERS, B.; CONDE, D.; PAPPAS, M. de C. R.; LIU, L.; MUCHLINSKI, A.; JIANG, H.; SHYU, C.; HUANG, P.; SEBASTIAN, J.; LAIBEN, C.; MEDLIN, A.; CAREY, S.; CARRELL, A. A.; CHEN, J.-G.; PERALES, M.; SWAMINATHAN, K.; ALLONA, I.; GRATTAPAGLIA, D.; COOPER, E. A.; THOLL, D.; VOGEL, V. P.; WESTON, D. J.; YANG, X.; BRUTNELL, T. P.; KELLOGG, E. A.; BAXTER, I.; UDVARDI, M.; TANG, Y.; MOCKLER, T. C.; JUENGER, T. E.; MULLET, J.; RENSING, S. A.; TUSKAN, G. A.; MERCHANT, S. S.; STACEY, G.; SCHMUTZ, J. |
|
Afiliação: |
AVINASH SREEDASYAM, Hudson Alpha Institute for Biotechnology, USA; CHRISTOPHER PLOTT, Hudson Alpha Institute for Biotechnology, USA; MD SHAKHAWAT HOSSAIN, University of Missouri, USA; JOHN T. LOVELL, Hudson Alpha Institute for Biotechnology, USA; JANE GRIMWOOD, Hudson Alpha Institute for Biotechnology, USA; JERRY W. JENKINS, Hudson Alpha Institute for Biotechnology, USA; CHRISTOPHER DAUM, Lawrence Berkeley National Laboratory, USA; KERRIE BARRY, Lawrence Berkeley National Laboratory, USA; JOSEPH CARLSON, Lawrence Berkeley National Laboratory, USA; SHENGQIANG SHU, Lawrence Berkeley National Laboratory, USA; JEREMY PHILLIPS, Lawrence Berkeley National Laboratory, USA; MOJGAN AMIREBRAHIMI, Lawrence Berkeley National Laboratory, USA; MATTHEW ZANE, Lawrence Berkeley National Laboratory, USA; MEI WANG, Lawrence Berkeley National Laboratory, USA; DAVID GOODSTEIN, Lawrence Berkeley National Laboratory, USA; FABIAN B. HAAS, University of Marburg, Germany; MANUEL HISS, University of Marburg, Germany; PIERRE-FRANÇOIS PERROUD, University of Marburg, Germany; SARA S. JAWDY, Oak Ridge National Laboratory, USA; YONGIL YANG, Oak Ridge National Laboratory, USA; RONGBIN HU, Oak Ridge National Laboratory, USA; JENIFER JOHNSON, Lawrence Berkeley National Laboratory, USA; JANETTE KROPAT, University of California, USA; SEAN D. GALLAHER, University of California, USA; ANNA LIPZEN, Lawrence Berkeley National Laboratory, USA; EUGENE V. SHAKIROV, University of Texas at Austin, USA; XIAOYU WENG, University of Texas at Austin, USA; IVONE TORRES-JEREZ, Noble Research Institute, USA; BROCK WEERS, Texas A&M University, USA; DANIEL CONDE, Universidad Politécnica de Madrid, Spain; MARILIA DE CASTRO RODRIGUES PAPPAS, Cenargen; LIFENG LIU, Lawrence Berkeley National Laboratory, USA; ANDREW MUCHLINSKI, Virginia Tech, USA; HUI JIANG, Donald Danforth Plant Science Center, USA; CHRISTINE SHYU, Donald Danforth Plant Science Center, USA; PU HUANG, Donald Danforth Plant Science Center, USA; JOSE SEBASTIAN, Donald Danforth Plant Science Center, USA; CAROL LAIBEN, Donald Danforth Plant Science Center, USA; ALYSSA MEDLIN, Donald Danforth Plant Science Center, USA; SANKALPI CAREY, Donald Danforth Plant Science Center, USA; ALYSSA A. CARRELL, Oak Ridge National Laboratory, USA; JIN-GUI CHEN, Oak Ridge National Laboratory, USA; MARIANO PERALES, Universidad Politécnica de Madrid, Madrid; KANKSHITA SWAMINATHAN, Hudson Alpha Institute for Biotechnology, Huntsville, USA; ISABEL ALLONA, Universidad Politécnica de Madrid, Madrid; DARIO GRATTAPAGLIA, Cenargen; ELIZABETH A. COOPER, Clemson University, USA; DOROTHEA THOLL, Virginia Tech, USA; JOHN P. VOGEL, Lawrence Berkeley National Laboratory, USA; DAVID J. WESTON, Oak Ridge National Laboratory, USA; XIAOHAN YANG, Oak Ridge National Laboratory, USA; THOMAS P. BRUTNELL, McClintock LLC, USA; ELIZABETH A. KELLOGG, Donald Danforth Plant Science Center, USA; IVAN BAXTER, Donald Danforth Plant Science Center, USA; MICHAEL UDVARDI, Noble Research Institute, USA; YUHONG TANG, Noble Research Institute, USA; TODD C. MOCKLER, Donald Danforth Plant Science Center, USA; THOMAS E. JUENGER, University of Texas at Austin, USA; JOHN MULLET, Texas A&M University, USA; STEFAN A. RENSING, University of Marburg, Germany; GERALD A. TUSKAN, Oak Ridge National Laboratory, USA; SABEEHA S. MERCHANT, Univerty of California, USA; GARY STACEY, University of Missouri, USA; JEREMY SCHMUTZ, Hudson Alpha Institute for Biotechnology, USA. |
|
Título: |
JGI Plant Gene Atlas: an updateable transcriptome resource to improve functional gene descriptions across the plant kingdom. |
|
Ano de publicação: |
2023 |
|
Fonte/Imprenta: |
Nucleic Acids Research, v. 51, n. 16, p. 8383-8401, 2023. |
|
DOI: |
https://doi.org/10.1093/nar/gkad616 |
|
Idioma: |
Inglês |
|
Notas: |
Na publicação: Marilia R. Pappas. |
|
Palavras-Chave: |
Gene Atlas plants; Joint Genome Institute (JGI); Ontology. |
|
Categoria do assunto: |
-- |
|
Marc: |
LEADER 02411naa a2200925 a 4500
001 2155579
005 2023-11-07
008 2023 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1093/nar/gkad616$2DOI
100 1 $aSREEDASYAM, A.
245 $aJGI Plant Gene Atlas$ban updateable transcriptome resource to improve functional gene descriptions across the plant kingdom.$h[electronic resource]
260 $c2023
500 $aNa publicação: Marilia R. Pappas.
653 $aGene Atlas plants
653 $aJoint Genome Institute (JGI)
653 $aOntology
700 1 $aPLOTT, C.
700 1 $aHOSSAIN, M. S.
700 1 $aLOVELL, J. T.
700 1 $aGRIMWOOD, J.
700 1 $aJENKINS, J. W.
700 1 $aDAUM, C.
700 1 $aBARRY, K.
700 1 $aCARLSON, J.
700 1 $aSHU, S.
700 1 $aPHILLIPS, J.
700 1 $aAMIREBRAHIMI, M.
700 1 $aZANE, M.
700 1 $aWANG, M.
700 1 $aGOODSTEIN, D.
700 1 $aHAAS, F. B.
700 1 $aHISS, M.
700 1 $aPERROUD, P.-F.
700 1 $aJAWDY, S. S.
700 1 $aYANG, Y.
700 1 $aHU, R.
700 1 $aJOHNSON, J.
700 1 $aKROPAT, J.
700 1 $aGALLAHER, S. D.
700 1 $aLIPZEN, A.
700 1 $aSHAKIROV, E. V.
700 1 $aWENG, X.
700 1 $aTORRES-JEREZ, I.
700 1 $aWEERS, B.
700 1 $aCONDE, D.
700 1 $aPAPPAS, M. de C. R.
700 1 $aLIU, L.
700 1 $aMUCHLINSKI, A.
700 1 $aJIANG, H.
700 1 $aSHYU, C.
700 1 $aHUANG, P.
700 1 $aSEBASTIAN, J.
700 1 $aLAIBEN, C.
700 1 $aMEDLIN, A.
700 1 $aCAREY, S.
700 1 $aCARRELL, A. A.
700 1 $aCHEN, J.-G.
700 1 $aPERALES, M.
700 1 $aSWAMINATHAN, K.
700 1 $aALLONA, I.
700 1 $aGRATTAPAGLIA, D.
700 1 $aCOOPER, E. A.
700 1 $aTHOLL, D.
700 1 $aVOGEL, V. P.
700 1 $aWESTON, D. J.
700 1 $aYANG, X.
700 1 $aBRUTNELL, T. P.
700 1 $aKELLOGG, E. A.
700 1 $aBAXTER, I.
700 1 $aUDVARDI, M.
700 1 $aTANG, Y.
700 1 $aMOCKLER, T. C.
700 1 $aJUENGER, T. E.
700 1 $aMULLET, J.
700 1 $aRENSING, S. A.
700 1 $aTUSKAN, G. A.
700 1 $aMERCHANT, S. S.
700 1 $aSTACEY, G.
700 1 $aSCHMUTZ, J.
773 $tNucleic Acids Research$gv. 51, n. 16, p. 8383-8401, 2023.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Recursos Genéticos e Biotecnologia (CENARGEN) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
Fechar
|
| Nenhum registro encontrado para a expressão de busca informada. |
|
|
