Data/hora: 05/06/2024 12:07:41

Biblioteca(s): 	Embrapa Pecuária Sudeste.	
Data corrente: 	02/12/2020	
Data da última atualização: 	02/12/2020	
Autoria: 	DINIZ, W. J. S.; ROSA, K. O. da; TIZIOTO, P. C.; MOURÃO, G. B.; OLIVEIRA, P. S. N. de; SOUZA, M. M. de; REGITANO, L. C. de A.	
Afiliação: 	Wellison J. S. Diniz, UFSCar; Kamila O. da Rosa, UNESP; Polyana C. Tizioto, NGS Soluções Genômicas; Gerson B. Mourão, USP, ESALQ; Priscila S. N. de Oliveira, UFSCAR; Marcela M. de Souza, Iowa State University; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE.	
Título: 	FABP1 and SLC2A5 expression levels affect feed efficiency-related traits.	
Ano de publicação: 	2020	
Fonte/Imprenta: 	Agri Gene, v. 15, p. 1-7, e100100, mar. 2020.	
DOI: 	https://doi.org/10.1016/j.aggene.2019.100100	
Idioma: 	Inglês	
Conteúdo: 	Improving the efficiency of production to reduce the environmental footprints is pivotal to the sustainability of livestock systems. Despite the advances in cattle feed efficiency (FE) measurement and identification of potential mechanisms involved, much is still unclear regarding the genetic and biological basis of this trait. Nevertheless, lipid and carbohydrate metabolism have been outlined as important in determining efficient and inefficient animals. To address the role of genes partaking in these processes and previously involved with residual feed intake (RFI), we carried out a liver expression profile in Nelore steers (n = 83). Six target genes (FABP1, FADS2, PPP1R26, RGS2, SLC2A5, and UCP2) were measured by qPCR analysis. A general linear mixed model approach was applied to associate them with dry matter intake (DMI), body weight (BW), metabolic BW (MBW, kg), DMI as a percentage of BW (DMI%BW), and average daily gain (ADG, kg/d). Residual feed intake (RFI), feed conversion ratio (FCR), feed efficiency (FE), Kleiber index (KI), and relative growth rate (RGR) were also evaluated. Our results support that increased expression of FABP1 gene was associated with enhanced values for RFI and DMI. Likewise, higher expression level of SLC2A5 was related to higher KI and RGR. There was no phenotypic correlation between RFI and ADG, BW, and MBW. The positive correlations between FABP1 and SLC2A5, and between FABP1 and FADS2 gene expression suggest a putative co-regulation affecting feed efficiency phenotypes.	
Palavras-Chave: 	Cattle feed efficiency; Relative growth rate.	
Thesaurus Nal: 	Average daily gain; Dry matter intake; Gene expression.	
Categoria do assunto: 	G Melhoramento Genético	
URL: 	http://ainfo.cnptia.embrapa.br/digital/bitstream/item/218621/1/FABP1-SLC2A5-Expression.pdf	
Registro original: 	Embrapa Pecuária Sudeste (CPPSE)	
Exemplares: 	CPPSE - (25177-1) - UPC - AP - DD - PROCI-2020.00091 - DIN - 2020.00142 - DIS