Data/hora: 25/06/2024 08:58:09

Biblioteca(s): 	Embrapa Amapá; Embrapa Amazônia Ocidental.	
Data corrente: 	07/03/2022	
Data da última atualização: 	17/11/2022	
Autoria: 	SEBASTIÃO, F. de A.; ROCHA, M. J. S.; BRANDÃO, F. R.; OLIVEIRA, M. I. B. de; SOUZA, D. C. de M; BARBOSA, B. C. do N.; MONTEIRO, P. C.; MAJOLO, C.; CRESCENCIO, R.; TAVARES-DIAS, M.; CHAGAS, E. C.	
Afiliação: 	FERNANDA DE ALEXANDRE SEBASTIÃO, FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DO AMAZONAS - FAPEAM; MARIA JULIETE SOUZA ROCHA, UNIVERSIDADE FEDERAL DO AMAZONAS - UFAM; FRANMIR RODRIGUES BRANDÃO, FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DO AMAZONAS - FAPEAM; MARIA INÊS BRAGA DE OLIVEIRA, UNIVERSIDADE FEDERAL DO AMAZONAS - UFAM; DAMY CAROLINE DE MELO SOUZA, UNIVERSIDADE FEDERAL DO AMAZONAS - UFAM; BRUNA CARLOS DO NASCIMENTO BARBOSA, UNINORTE LAUREATE INTERNATIONAL UNIVERSITIES; PATRÍCIA CASTRO MONTEIRO, SECRETARIA MUNICIPAL DE EDUCAÇÃO - MANAUS; CLAUDIA MAJOLO, CPAA; ROGER CRESCENCIO, CPAA; MARCOS TAVARES DIAS, CPAF-AP; EDSANDRA CAMPOS CHAGAS, CPAA.	
Título: 	Evaluation of the clinical safety and efficacy of fenbendazole and levamisole in the control of Neoechinorhynchus buttnerae in Colossoma macropomum: Acanthocephalosis treatments.	
Ano de publicação: 	2022	
Fonte/Imprenta: 	Aquaculture International, v. 30, p. 1341-1351, 2022.	
DOI: 	https://doi.org/10.1007/s10499-022-00854-2	
Idioma: 	Inglês	
Conteúdo: 	Occurrences of parasitic infections caused by Neoechinorhynchus buttnerae in Colossoma macropomum (tambaqui), especially in the northern region of Brazil, have increased in the
past two decades and have caused economic losses in tambaqui production. The aim of this study was to evaluate the in vivo efcacy and clinical safety of fenbendazole and levamisole in controlling and treating N. buttnerae in tambaqui for 30 days. Juvenile tambaqui naturally infected with N. buttnerae were distributed in 15 tanks (n = 12 per 1,000 L-tank),
constituting fve treatments, in triplicate. Treatments were administered via diet (mg kg - 1 of live weight): control (0 mg kg - 1), F1 (100 mg kg - 1 of fenbendazole), F2 (200 mg kg - 1 of fenbendazole), L1 (200 mg kg - 1 of levamisole), and L2 (300 mg kg - 1 of levamisole). Fish survival rate was 100% during the entire experimental period. Fenbendazole treatments were not efective against N. buttnerae; however, L1 and L2 showed efcacy of 73.4 and 99.15%, respectively. Treatments with fenbendazole or levamisole did not afect the growth parameters of tambaqui. F1 and F2 showed signifcant reduction in the hemato- crit values when compared to L1, and hemoglobin values were signifcantly reduced in F1 when compared to L1, L2, and the control group. There were no signifcant diferences in RBC, MCV, and CHCM. The plasma glucose value was statistically lower in F1 than in the L1 (p = 0.03) and L2 (p = 0.02) treatments. For alanine aminotransferase, there was a signifcant reduction (p = 0.004) in the F1 and F2 groups compared to the L2 group. No statistical diference was observed for aspartate aminotransferase among the treatments. More studies are warranted to further evaluate other therapeutic strategies using shorter periods for controlling and efciently treating N. buttnerae.	
Palavras-Chave: 	Acantocephalan; Antiparasitic treatment; Neoechinorhynchus buttnerae.	
Thesagro: 	Colossoma Macropomum; Peixe de Água Doce; Tambaqui; Verminose.	
Categoria do assunto: 	--
L Ciência Animal e Produtos de Origem Animal	
Registro original: 	Embrapa Amapá (CPAF-AP)	
Exemplares: 	CPAA - (38689-1) - UPC - AP - DD -  -  -  - DIS
CPAF-AP - (18534-1) - UPC - AP - DD -  -  -  - DIS