Data/hora: 20/06/2024 07:58:20

Biblioteca(s): 	Embrapa Gado de Leite.	
Data corrente: 	02/06/2022	
Data da última atualização: 	14/03/2023	
Autoria: 	CARMO, I. A. D.; SOUZA, A. K. N. de; FAYER, L.; MUNK, M.; BRANDAO, H. de M.; OLIVEIRA, L. F. C. de; BANDEIRA, S.; CAVALLINI, G. S.; SOUZA, N. L. G. D. de.	
Afiliação: 	IAGO AGUIAR DIAS CARMO, Universidade Federal do Tocantins; ALINE KARLA NOLBERTO DE SOUZA, Universidade Federal do Tocantins; LEONARA FAYER, Universidade Federal de Juiz de Fora; MICHELE MUNK, Universidade Federal de Juiz de Fora; HUMBERTO DE MELLO BRANDAO, CNPGL; LUIZ FERNANDO CAPPA DE OLIVEIRA, Universidade Federal de Juiz de Fora; STEPHANE BANDEIRA; GRASIELE SOARES CAVALLINI, Universidade Federal do Tocantins; NELSON LUIS GONÇALVES DIAS DE SOUZA, Universidade Federal do Tocantins.	
Título: 	Cytotoxicity and bactericidal activity of alginate/polyethylene glycol films with zinc oxide or silicon oxide nanoparticles for food packaging.	
Ano de publicação: 	2022	
Fonte/Imprenta: 	International Journal of Polymeric Materials and Polymeric Biomaterials, v. 72, n. 8, p. 577-588, 2022.	
Idioma: 	Inglês	
Conteúdo: 	In the food industry, packaging is used to protect food. However, traditional packaging has serious environmental impacts. Thus, studies have investigated packaging composed of biodegradable polymers. Accordingly, the present study aimed to obtain and characterize polymeric films of sodium alginate and polyethylene glycol crosslinked with tetraethoxysilane and doped with nano-zinc oxide or nano-silicon oxide and evaluate their cytotoxicity and bactericidal activity against coliforms and Escherichia coli. The nanoparticles and crosslinked materials were characterized using infrared and Raman spectroscopy. The cytotoxicity of the films was evaluated using a direct contact assay with a bovine fibroblast cell model. The bactericidal activity of the films was assessed by determining whether the contamination indicators were activated. The average sizes of the ZnO and SiO2 nanoparticles were 408.3 and 125.3?nm, respectively, and their zeta potentials were ?31.6 and ?31.1?mV, respectively. Cell growth inhibition zone tests indicated that 75 ALG/25 PEG/SiO2 was slightly toxic, while 25 ALG/75 PEG/ZnO exhibited mild toxicity. Cell area analysis showed that the addition of SiO2 decreased the cytotoxicity of the obtained films. Finally, it was possible to observe the inactivation of both contamination bioindicators. Therefore, films containing nanoparticles could be promising biomaterials for packaging in the food industry.	
Palavras-Chave: 	Agente antimicrobiano; Atividade bactericida; Citotoxicidade; Nanotecnologia.	
Thesagro: 	Alimento; Embalagem; Indústria Alimentícia.	
Categoria do assunto: 	X Pesquisa, Tecnologia e Engenharia	
Registro original: 	Embrapa Gado de Leite (CNPGL)	
Exemplares: 	CNPGL - (25669-1) - UPC - AP - DD -  -  -  - DIS