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Registro Completo |
Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
Data corrente: |
27/11/2023 |
Data da última atualização: |
14/12/2023 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
SOUZA, S. C. R.; PINHEIRO, R. R.; PEIXOTO, R. M.; SOUSA, A. L. M. de; ANDRIOLI, A.; LIMA, A. M. C.; MENDES, B. K. M.; MAGALHÃES, N. M. de A.; AMARAL, G. P.; TEIXEIRA, M. F. da S. |
Afiliação: |
SAMARA CRISTINA ROCHA SOUZA, STATE UNIVERSITY OF CEARÁ, VIROLOGY LABORATORY (LABOVIR); RAYMUNDO RIZALDO PINHEIRO, CNPC; RENATO MESQUITA PEIXOTO, VALE DO SALGADO UNIVERSITY CENTER (UNIVS); ANA LÍDIA MADEIRA DE SOUSA, FACULDADE EDUCAR DA IBIAPABA; ALICE ANDRIOLI PINHEIRO, CNPC; ANA MILENA CÉSAR LIMA; BÁRBARA KAREN MARQUES MENDES, FEDERAL UNIVERSITY OF PIAUÍ; NATHÁLIA MARIA DE ANDRADE MAGALHÃES, FEDERAL UNIVERSITY OF CAMPINA GRANDE; GABRIEL PAULA AMARAL, VALE DO ACARAÚ STATE UNIVERSITY; MARIA FÁTIMA DA SILVA TEIXEIRA, STATE UNIVERSITY OF CEARÁ, VIROLOGY LABORATORY (LABOVIR). |
Título: |
In vivo evaluation of the antiretroviral activity of Melia azedarach against small ruminant lentiviruses in goat colostrum and milk. |
Ano de publicação: |
2023 |
Fonte/Imprenta: |
Brazilian Journal of Microbiology, v. 54, n. 3, Sept. 2023. |
DOI: |
| https://doi.org/10.1038/s41598-023-31455-5 |
Idioma: |
Inglês |
Notas: |
On-line first. |
Conteúdo: |
Abstract: This study aimed to evaluate in vivo the use of the extract from the leaves of Melia azedarach in the ethyl acetate fraction at a concentration of 150 µg/mL as an antiretroviral treatment against small ruminant lentiviruses (SRLV) in goat colostrum, and milk with a 90-min action. Two groups of six kids were treated with the extract. One group received three supplies of colostrum from does naturally positive for SRLV, treated with the ethyl acetate fraction of M. azedarach (EAF-MA) for three days, while the other group consumed milk from does also carrying the virus with the respective extract twice a day for five days. After undergoing treatment, all animals began to receive thermized milk until weaning (60 days) and were monitored for six months using nested polymerase chain reaction (nPCR) and western blot (WB) tests. The study revealed cumulative percentages of positive animals in WB or nPCR in the milk group of 66.66% on the seventh day, 83.33% in the following week, and 100% at 120 days, while the colostrum group showed values of 66.66% at 14 days, 83.33% at 90 days, and 100% at 120 days. Variation and intermittency were observed in viral detection, but all animals tested positive in WB or nPCR at some point. A potential delay in infection was observed, which was more significant in the colostrum group. The need for the combination of serological and molecular tests for a more efficient detection of the disease is also emphasized. |
Palavras-Chave: |
Antimicrobial properties; Antiviral action; Antiviral plants; Lactogenic transmission; Natural products; Phytochemistry. |
Thesagro: |
Meliaceae. |
Thesaurus Nal: |
Goat diseases; Goats; Lentivirus; Medicinal plants. |
Categoria do assunto: |
H Saúde e Patologia |
Marc: |
LEADER 02655naa a2200385 a 4500 001 2158756 005 2023-12-14 008 2023 bl uuuu u00u1 u #d 024 7 $a| https://doi.org/10.1038/s41598-023-31455-5$2DOI 100 1 $aSOUZA, S. C. R. 245 $aIn vivo evaluation of the antiretroviral activity of Melia azedarach against small ruminant lentiviruses in goat colostrum and milk.$h[electronic resource] 260 $c2023 500 $aOn-line first. 520 $aAbstract: This study aimed to evaluate in vivo the use of the extract from the leaves of Melia azedarach in the ethyl acetate fraction at a concentration of 150 µg/mL as an antiretroviral treatment against small ruminant lentiviruses (SRLV) in goat colostrum, and milk with a 90-min action. Two groups of six kids were treated with the extract. One group received three supplies of colostrum from does naturally positive for SRLV, treated with the ethyl acetate fraction of M. azedarach (EAF-MA) for three days, while the other group consumed milk from does also carrying the virus with the respective extract twice a day for five days. After undergoing treatment, all animals began to receive thermized milk until weaning (60 days) and were monitored for six months using nested polymerase chain reaction (nPCR) and western blot (WB) tests. The study revealed cumulative percentages of positive animals in WB or nPCR in the milk group of 66.66% on the seventh day, 83.33% in the following week, and 100% at 120 days, while the colostrum group showed values of 66.66% at 14 days, 83.33% at 90 days, and 100% at 120 days. Variation and intermittency were observed in viral detection, but all animals tested positive in WB or nPCR at some point. A potential delay in infection was observed, which was more significant in the colostrum group. The need for the combination of serological and molecular tests for a more efficient detection of the disease is also emphasized. 650 $aGoat diseases 650 $aGoats 650 $aLentivirus 650 $aMedicinal plants 650 $aMeliaceae 653 $aAntimicrobial properties 653 $aAntiviral action 653 $aAntiviral plants 653 $aLactogenic transmission 653 $aNatural products 653 $aPhytochemistry 700 1 $aPINHEIRO, R. R. 700 1 $aPEIXOTO, R. M. 700 1 $aSOUSA, A. L. M. de 700 1 $aANDRIOLI, A. 700 1 $aLIMA, A. M. C. 700 1 $aMENDES, B. K. M. 700 1 $aMAGALHÃES, N. M. de A. 700 1 $aAMARAL, G. P. 700 1 $aTEIXEIRA, M. F. da S. 773 $tBrazilian Journal of Microbiology$gv. 54, n. 3, Sept. 2023.
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Embrapa Caprinos e Ovinos (CNPC) |
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Biblioteca(s): |
Embrapa Amazônia Ocidental. |
Data corrente: |
23/02/2010 |
Data da última atualização: |
05/04/2022 |
Tipo da produção científica: |
Artigo em Anais de Congresso / Nota Técnica |
Autoria: |
DIAS, M. C.; BARRETO, J. F.; PAMPLONA, A. M. S. R. |
Afiliação: |
MIGUEL COSTA DIAS, CPAA; JOAO FERDINANDO BARRETO, CPAA; ANA MARIA SANTA ROSA PAMPLONA, CPAA. |
Título: |
Avaliação e seleção de variedades e híbridos de mandioca no Estado do Amazonas. |
Ano de publicação: |
2009 |
Fonte/Imprenta: |
In: REUNIÃO TÉCNICA DE PESQUISA E DESENVOLVIMENTO DA EMBRAPA AMAZÔNIA OCIDENTAL, 4., 2009, Manaus. Anais... Manaus: Embrapa Amazônia Ocidental, 2009. p. 108-109. (Embrapa Amazônia Ocidental. Documentos, 73). |
Idioma: |
Português |
Conteúdo: |
Este trabalho teve como objetivo selecionar genótipos adaptados aos diferentes ecossistemas do Estado do Amazonas, para consumo fresco, farinha de mesa e para a indústria de fécula. |
Palavras-Chave: |
Amazonas; Brasil. |
Thesagro: |
Genótipo; Mandioca; Manihot Esculenta; Variedade. |
Categoria do assunto: |
-- |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/64644/1/Doc-73p110-111.pdf
|
Marc: |
LEADER 00938nam a2200205 a 4500 001 1685071 005 2022-04-05 008 2009 bl uuuu u00u1 u #d 100 1 $aDIAS, M. C. 245 $aAvaliação e seleção de variedades e híbridos de mandioca no Estado do Amazonas.$h[electronic resource] 260 $aIn: REUNIÃO TÉCNICA DE PESQUISA E DESENVOLVIMENTO DA EMBRAPA AMAZÔNIA OCIDENTAL, 4., 2009, Manaus. Anais... Manaus: Embrapa Amazônia Ocidental, 2009. p. 108-109. (Embrapa Amazônia Ocidental. Documentos, 73).$c2009 520 $aEste trabalho teve como objetivo selecionar genótipos adaptados aos diferentes ecossistemas do Estado do Amazonas, para consumo fresco, farinha de mesa e para a indústria de fécula. 650 $aGenótipo 650 $aMandioca 650 $aManihot Esculenta 650 $aVariedade 653 $aAmazonas 653 $aBrasil 700 1 $aBARRETO, J. F. 700 1 $aPAMPLONA, A. M. S. R.
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