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Registro Completo |
Biblioteca(s): |
Embrapa Instrumentação. |
Data corrente: |
20/04/2023 |
Data da última atualização: |
15/01/2024 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
GOMES, N. O.; PASCHOALIN, R. T.; BILLATO, S.; SORIGOTTI, A. R.; FARINAS, C. S.; MATTOSO, L. H. C.; MACHADO, S. A. S.; OLIVEIRA JR., O. N.; RAYMUNDO-PEREIRA, P. A. |
Afiliação: |
CRISTIANE SANCHEZ FARINAS, CNPDIA; LUIZ HENRIQUE CAPPARELLI MATTOSO, CNPDIA. |
Título: |
Flexible, Bifunctional Sensing Platform Made with Biodegradable Mats for Detecting Glucose in Urine. |
Ano de publicação: |
2023 |
Fonte/Imprenta: |
ACS Sustainable Chemistry & Engineering, v. 11, 2023. |
Páginas: |
2209–2218 |
ISSN: |
2168-0485 |
DOI: |
https://doi.org/10.1021/acssuschemeng.2c05438 |
Idioma: |
Inglês |
Conteúdo: |
: We report on a flexible, bifunctional platform made with solution-blow spinning fiber mats of polylactic acid (PLA) and polyethylene glycol (PEG). The PLA/PEG mats were designated bifunctional because they were used as a substrate for screenprinted carbon electrodes (SPCEs) and as a matrix to attach glucose oxidase (GOx)covalently. By attaching GOx only on the fiber mats, and not on the SPCE, the detectionof hydrogen peroxide generated from glucose oxidation by the enzyme was efficient,especially with Prussian blue (PB) nanoparticles electrodeposited on the SPCE surface.The bifunctional device detected hydrogen peroxide (H2O2) in synthetic and humanurine at a low applied potential (0 V vs Ag/AgCl) in the range from 1.0 to 6.0 mM, witha detection limit of 0.197 mM, being also interference-free. The biosensor whose cost is
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Palavras-Chave: |
Biodegradable and biocompatible mat; Glucose electrochemical biosensor; Polylactic acid (PLA); Solution-blow spinning; Urine non-invasive sample. |
Categoria do assunto: |
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Marc: |
LEADER 02286naa a2200313 a 4500 001 2153278 005 2024-01-15 008 2023 bl uuuu u00u1 u #d 022 $a2168-0485 024 7 $ahttps://doi.org/10.1021/acssuschemeng.2c05438$2DOI 100 1 $aGOMES, N. O. 245 $aFlexible, Bifunctional Sensing Platform Made with Biodegradable Mats for Detecting Glucose in Urine.$h[electronic resource] 260 $c2023 300 $a2209–2218 520 $a: We report on a flexible, bifunctional platform made with solution-blow spinning fiber mats of polylactic acid (PLA) and polyethylene glycol (PEG). The PLA/PEG mats were designated bifunctional because they were used as a substrate for screenprinted carbon electrodes (SPCEs) and as a matrix to attach glucose oxidase (GOx)covalently. By attaching GOx only on the fiber mats, and not on the SPCE, the detectionof hydrogen peroxide generated from glucose oxidation by the enzyme was efficient,especially with Prussian blue (PB) nanoparticles electrodeposited on the SPCE surface.The bifunctional device detected hydrogen peroxide (H2O2) in synthetic and humanurine at a low applied potential (0 V vs Ag/AgCl) in the range from 1.0 to 6.0 mM, witha detection limit of 0.197 mM, being also interference-free. The biosensor whose cost is<US$ 0.25 per unit (estimated from the price of the materials used) had performance comparable to the gold standard method while measuring glucose in human urine samples, in addition to exhibiting a rapid response and long lifetime. The design of the bifunctional device is generic and may be extended to other biosensors for on-site monitoring as well as for wearable devices and inmonitoring the environment and water in varied resources 653 $aBiodegradable and biocompatible mat 653 $aGlucose electrochemical biosensor 653 $aPolylactic acid (PLA) 653 $aSolution-blow spinning 653 $aUrine non-invasive sample 700 1 $aPASCHOALIN, R. T. 700 1 $aBILLATO, S. 700 1 $aSORIGOTTI, A. R. 700 1 $aFARINAS, C. S. 700 1 $aMATTOSO, L. H. C. 700 1 $aMACHADO, S. A. S. 700 1 $aOLIVEIRA JR., O. N. 700 1 $aRAYMUNDO-PEREIRA, P. A. 773 $tACS Sustainable Chemistry & Engineering$gv. 11, 2023.
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Registros recuperados : 3 | |
1. | | SORIGOTTI, A. R.; PASCHOALIN, R. T.; SILVA, R. R.; OTONI, C. G.; BARUD, H. S.; RIBEIRO, S. J. L.; OLIVEIRA JR, O. N.; MATTOSO, L. H. C. Nanofibras de fibroína de seda obtidas por fiação por sopro em solução para aplicações biomédicas. In: JORNADA CIENTÍFICA - EMBRAPA SÃO CARLOS, 11., 2019, São Carlos, SP. Anais... São Carlos: Embrapa Pecuária Sudeste: Embrapa Instrumentação, 2019. Editores técnicos: Alexandre Berndt, Ana Rita de Araujo Nogueira, Lea Chapaval, Marcelo Mattos Cavallari, Manuel Antonio Chagas Jacinto. 57 Embrapa Pecuária Sudeste. Documentos, 134.Tipo: Resumo em Anais de Congresso |
Biblioteca(s): Embrapa Instrumentação. |
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2. | | GOMES, N. O.; PASCHOALIN, R. T.; BILLATO, S.; SORIGOTTI, A. R.; FARINAS, C. S.; MATTOSO, L. H. C.; MACHADO, S. A. S.; OLIVEIRA JR, O. N.; RAYMUNDO-PEREIRA, P. A. Biodegradable Mats for the Design of Bifunctional Biosensors for Glucose Detection in Urine. Engineering Proceedings, v. 35, n. 1, 2023. 8 p.Tipo: Artigo em Periódico Indexado |
Biblioteca(s): Embrapa Instrumentação. |
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3. | | GOMES, N. O.; PASCHOALIN, R. T.; BILLATO, S.; SORIGOTTI, A. R.; FARINAS, C. S.; MATTOSO, L. H. C.; MACHADO, S. A. S.; OLIVEIRA JR., O. N.; RAYMUNDO-PEREIRA, P. A. Flexible, Bifunctional Sensing Platform Made with Biodegradable Mats for Detecting Glucose in Urine. ACS Sustainable Chemistry & Engineering, v. 11, 2023. 2209–2218Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Instrumentação. |
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Registros recuperados : 3 | |
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