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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
01/08/1992 |
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Data da última atualização: |
01/12/2023 |
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Autoria: |
SMITH, W. D.; JACKSON, F.; JACKSON, E.; WILLIAMS, J. |
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Título: |
Age immunity to ostertagia circuncincta comparison to the local immune responses of 4 1/2 and 10-Month-old lambs. |
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Ano de publicação: |
1985 |
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Fonte/Imprenta: |
Journal of Comparative Pathology, v. 95, n. 2, p. 235-245, Apr. 1985. |
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DOI: |
https://doi.org/10.1016/0021-9975(85)90010-6 |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: In 2 experiments, the local immune response to infection with 50 000 O. circumcincta was monitored in previously infected lambs by following changes in the composition of gastric lymph. The previously infected lambs were partially resistant to the challenge in that they harboured a greater proportion of early fourth stage parasites and that the developing larvae recovered from them were distinctly shorter than those present in controls. They also exhibited a secondary local immune response in the gastric lymph consisting of increases in the output of lymphoblasts and IgA cells which peaked 3 to 5 days after challenge, followed by increases in lymph IgA and IgA anti-larval antibody on days 6 and 7. The size of the total IgA response in a sheep was highly correlated with the degree of stunting of its larvae, suggesting that IgA antibody can reduce the growth of developing Ostertagia. When compared with the results of 2 identically designed experiments carried out previously in 10-month-old sheep, the younger lambs were measurably less resistant to challenge and most aspects of the magnitude of the local immune response were significantly depressed, although the timing of the response was similar. It is suggested that this poorly developed ability to mount a secondary mucosal immune response may explain the relative failure of the younger lamb to develop resistance to gastro-intestinal nematodes. |
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Palavras-Chave: |
Nematode gastrintestinal; Trichostrongyloidiasis / veterinary*. |
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Thesagro: |
Ovino; Parasitologia; Resistência. |
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Thesaurus Nal: |
Biosynthesis; Gastrointestinal nematodes; Immunoglobulin A; Immunology; Kinetics; Lymphocytes; Ostertagia; Regression analysis; Sheep diseases. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02459naa a2200337 a 4500
001 1521259
005 2023-12-01
008 1985 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1016/0021-9975(85)90010-6$2DOI
100 1 $aSMITH, W. D.
245 $aAge immunity to ostertagia circuncincta comparison to the local immune responses of 4 1/2 and 10-Month-old lambs.$h[electronic resource]
260 $c1985
520 $aAbstract: In 2 experiments, the local immune response to infection with 50 000 O. circumcincta was monitored in previously infected lambs by following changes in the composition of gastric lymph. The previously infected lambs were partially resistant to the challenge in that they harboured a greater proportion of early fourth stage parasites and that the developing larvae recovered from them were distinctly shorter than those present in controls. They also exhibited a secondary local immune response in the gastric lymph consisting of increases in the output of lymphoblasts and IgA cells which peaked 3 to 5 days after challenge, followed by increases in lymph IgA and IgA anti-larval antibody on days 6 and 7. The size of the total IgA response in a sheep was highly correlated with the degree of stunting of its larvae, suggesting that IgA antibody can reduce the growth of developing Ostertagia. When compared with the results of 2 identically designed experiments carried out previously in 10-month-old sheep, the younger lambs were measurably less resistant to challenge and most aspects of the magnitude of the local immune response were significantly depressed, although the timing of the response was similar. It is suggested that this poorly developed ability to mount a secondary mucosal immune response may explain the relative failure of the younger lamb to develop resistance to gastro-intestinal nematodes.
650 $aBiosynthesis
650 $aGastrointestinal nematodes
650 $aImmunoglobulin A
650 $aImmunology
650 $aKinetics
650 $aLymphocytes
650 $aOstertagia
650 $aRegression analysis
650 $aSheep diseases
650 $aOvino
650 $aParasitologia
650 $aResistência
653 $aNematode gastrintestinal
653 $aTrichostrongyloidiasis / veterinary*
700 1 $aJACKSON, F.
700 1 $aJACKSON, E.
700 1 $aWILLIAMS, J.
773 $tJournal of Comparative Pathology$gv. 95, n. 2, p. 235-245, Apr. 1985.
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| Registros recuperados : 7 | |
| 3. |  | MATOS, A. F. I. M. de; NOBRE, C. O. R.; MONTEIRO, J. P.; BEVILAQUA, C. M. L.; SMITH, W. D.; TEIXEIRA, M. Attempt to control Haemonchus contortus in dairy goats with Barbervax®, a vaccine derived from the nematode gut membrane glycoproteins. Small Ruminant Research, Amsterdam, v. 151, p. 1-4, June, 2017.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Caprinos e Ovinos. |
|    |
| 5. | | NOBRE, C. O. R.; MATOS, A. F. I. M.; VIEIRA, L. da S.; MONTEIRO, J. P.; SMITH, W. D.; TEIXEIRA, M. Haemonchus contortus control and performance of dairy goats vaccinated with Barbervax®: preliminary data. In: INTERNATIONAL CONFERENCE OF THE WORLD ASSOCIATION FOR THE ADVANCEMENT OF VETERINARY PARASITOLOGY, 26., 2017, Kuala Lumpur, Malaysia. Abstract book. Perth: WAAVP, 2017. p. 467. Abstract 4883. In conjunction with 53rd MSPTM Annual Conference.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Caprinos e Ovinos. |
|  |
| 6. | | TEIXEIRA, M.; MATOS, A. F. I. M.; ALBUQUERQUE, F. H. M. A. R. de; BASSETTO, C. C.; SMITH, W. D.; MONTEIRO, J. P. Strategic vaccination of hair sheep against Haemonchus contortus. Parasitology Research, v. 118, n. 8, p. 2383-2388, Aug. 2019.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Caprinos e Ovinos. |
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| 7. | | SMITH, W. D.; NEWLANDS, G.; FITZPATRICK, J.; SPICKETT, A.; AMARANTE, A.; SOUZA, C. J. H. de; BENAVIDES, M. V.; BESIER, B. Towards a commercial vaccine for Haemonchosis in ruminants. In: INTERNATIONAL CONFERENCE OF THE WORLD ASSOCIATION FOR THE ADVANCEMENT OF VETERINARY PARASITOLOGY, 23., 2011, Buenos Aires. Proceedings... Buenos Aires: WAAVP, 2011. 1 CD-ROM.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Pecuária Sul. |
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| Registros recuperados : 7 | |
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| Nenhum registro encontrado para a expressão de busca informada. |
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