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Registro Completo |
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Biblioteca(s): |
Embrapa Meio Norte / UEP-Parnaíba. |
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Data corrente: |
12/07/1995 |
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Data da última atualização: |
12/07/1995 |
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Autoria: |
GODWIN, D.; SLATER, J. H. |
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Afiliação: |
University of Warwick. |
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Título: |
The influence of the growth environment on the stability of a drug resistance plasmid in Escherichia coli K12. |
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Ano de publicação: |
1979 |
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Fonte/Imprenta: |
Journal of General Microbiology, v.111, p.201-210, 1979. |
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Idioma: |
Inglês |
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Notas: |
Separata. |
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Conteúdo: |
Populations of Escherichia coli K12 containing the plasmid TP120 whichcoded for resistance to ampicillin, streptomycin, sulphonamide and tetracycline were grown in a chemostat under carbon-limited and phosphorus-limited conditions. With time, resistance to one or more of the drugs was lost, resulting in the production of mutant populations which were more competitive than the parent population. The resistance to tetracycline was always lost under both carbon and phosphorus limitations,but resistance to the other three drugs was lost only during phosphate-limited growth. Strains of E. coli which had lost resistance to one or more of the drugs were capable of higher maximum specific growth rates than the parent strain. |
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Palavras-Chave: |
Ampicilina; Plasmidio; Resistencia Tetraciclina. |
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Thesagro: |
Escherichia Coli. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 01296naa a2200193 a 4500
001 1074977
005 1995-07-12
008 1979 bl --- 0-- u #d
100 1 $aGODWIN, D.
245 $aThe influence of the growth environment on the stability of a drug resistance plasmid in Escherichia coli K12.
260 $c1979
500 $aSeparata.
520 $aPopulations of Escherichia coli K12 containing the plasmid TP120 whichcoded for resistance to ampicillin, streptomycin, sulphonamide and tetracycline were grown in a chemostat under carbon-limited and phosphorus-limited conditions. With time, resistance to one or more of the drugs was lost, resulting in the production of mutant populations which were more competitive than the parent population. The resistance to tetracycline was always lost under both carbon and phosphorus limitations,but resistance to the other three drugs was lost only during phosphate-limited growth. Strains of E. coli which had lost resistance to one or more of the drugs were capable of higher maximum specific growth rates than the parent strain.
650 $aEscherichia Coli
653 $aAmpicilina
653 $aPlasmidio
653 $aResistencia Tetraciclina
700 1 $aSLATER, J. H.
773 $tJournal of General Microbiology$gv.111, p.201-210, 1979.
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Registro original: |
Embrapa Meio Norte / UEP-Parnaíba (CPAMN-UEPP) |
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