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Registro Completo |
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Biblioteca(s): |
Embrapa Recursos Genéticos e Biotecnologia. |
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Data corrente: |
27/02/2012 |
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Data da última atualização: |
28/02/2023 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
CHEAVEGATTI VIANOTTO, A.; ABREU, H. M. C. de; ARRUDA, P.; BESPALHOK FILHO, J. C.; BURNQUIST, W. L.; CRESTE, S.; CIERO, L. di; FERRO, J. A.; FIGUEIRA, A. V. de O.; FIULGUEIRAS, T. de S.; SA, M. F. G. de; GUZZO, E. C.; HOFFMANN, H. P.; LANDELL, M. G. de A.; MACEDO, N.; MATSUOKA, S.; REINACH, F. de C.; PINTO, E. R. de C.; SILVA, W. J. da; SILVA FILHO, M. de C.; ULIAN, E. C. |
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Afiliação: |
ADRIANA CHEAVEGATTIVIANOTTO; HELLEN MARILIA COUTO DE ABREU; PAULO ARRUDA, UNIVERSIDADE ESTADUAL DE CAMPINAS; JOAO CARLOS BESPALHOK FILHO, UFPR; WILLIAN LEE BURNQUIST; SILVANA CRESTE, IAC; LUCIANA DI CIERO; JESUS APARECIDO FERRO; ANTONIO VARGAS DE OLIVEIRA FIGUEIRA, CENA/USP; TARCISIO DE SOUSA FILGUEIRA; MARIA FATIMA GROSSI DE SA, CENARGEN; ELIO CESAR GUZZO, CPATC; HERMANN PAULO HOFFMANN; MARCOS GUIMARAES DE ANDRADE LANDELL; NEWTON MACEDO; SUZUO MATSUOKA; FERNANDO DE CASTRO REINACH; EDUARDO ROMANO DE CAMPOS PINTO, CENARGEN; WILLIAN JOSE DA SILVA; MARCIO DE CASTRO SILVA FILHO; EUGENIO CEZAR ULIAN. |
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Título: |
Sugarcane (Saccharum X officinarum): a reference study for the regulation of genetically modified cultivars in Brazil. |
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Ano de publicação: |
2011 |
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Fonte/Imprenta: |
Tropical Plant Biology, v. 4, p. 62-89, 2011. |
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Idioma: |
Inglês |
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Palavras-Chave: |
Artigo em periódico; Cana-de-açúcar. |
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Thesaurus Nal: |
sugarcane. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/183558/1/12042-2011-Article-9068.pdf
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Marc: |
LEADER 01149naa a2200385 a 4500
001 1916699
005 2023-02-28
008 2011 bl uuuu u00u1 u #d
100 1 $aCHEAVEGATTI VIANOTTO, A.
245 $aSugarcane (Saccharum X officinarum)$ba reference study for the regulation of genetically modified cultivars in Brazil.$h[electronic resource]
260 $c2011
650 $asugarcane
653 $aArtigo em periódico
653 $aCana-de-açúcar
700 1 $aABREU, H. M. C. de
700 1 $aARRUDA, P.
700 1 $aBESPALHOK FILHO, J. C.
700 1 $aBURNQUIST, W. L.
700 1 $aCRESTE, S.
700 1 $aCIERO, L. di
700 1 $aFERRO, J. A.
700 1 $aFIGUEIRA, A. V. de O.
700 1 $aFIULGUEIRAS, T. de S.
700 1 $aSA, M. F. G. de
700 1 $aGUZZO, E. C.
700 1 $aHOFFMANN, H. P.
700 1 $aLANDELL, M. G. de A.
700 1 $aMACEDO, N.
700 1 $aMATSUOKA, S.
700 1 $aREINACH, F. de C.
700 1 $aPINTO, E. R. de C.
700 1 $aSILVA, W. J. da
700 1 $aSILVA FILHO, M. de C.
700 1 $aULIAN, E. C.
773 $tTropical Plant Biology$gv. 4, p. 62-89, 2011.
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Registro original: |
Embrapa Recursos Genéticos e Biotecnologia (CENARGEN) |
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Biblioteca |
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Origem |
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Classificação |
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Registro |
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Voltar
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Registro Completo
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Biblioteca(s): |
Embrapa Meio Ambiente. |
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Data corrente: |
19/08/2021 |
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Data da última atualização: |
28/12/2021 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
LUIS, A. I. S.; CAMPOS, E. V. R.; OLIVEIRA, J. L. de; VALLIM, J. H.; PROENÇA, P. L. de F.; CASTANHA, R. F.; CASTRO, V. L. S. S. de; FRACETO, L. F. |
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Afiliação: |
ANGÉLICA IRASEMA SIBAJA LUIS, ICTS-UNESP; ESTEFÂNIA VANGELIE RAMOS CAMPOS, UFABC; JHONES LUIZ DE OLIVEIRA, ICTS-UNESP; JOSE HENRIQUE VALLIM, CNPMA; PATRÍCIA LUIZA DE FREITAS PROENÇA, ICTS-UNESP; RODRIGO FERNANDES CASTANHA, CNPMA; VERA LUCIA SCHERHOLZ S DE CASTRO, CNPMA; LEONARDO FERNANDES FRACETO, ICTS-UNESP. |
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Título: |
Ecotoxicity evaluation of polymeric nanoparticles loaded with ascorbic acid for fish nutrition in aquaculture. |
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Ano de publicação: |
2021 |
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Fonte/Imprenta: |
Journal of Nanobiotechnology, v. 19, n. 1, article 163, 2021. |
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Páginas: |
p. 1-22. |
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ISSN: |
1477-3155 |
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DOI: |
https://doi.org/10.1186/s12951-021-00910-8 |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: Background: Ascorbic acid (AA) is a micronutrient essential for the mechanisms of reproduction, growth, and defense in fish. However, the biosynthesis of this micronutrient does not occur in fish, so it must be supplied with food. A difficulty is that plain AA is unstable, due to the effects of light, high temperature, and oxygen, among others. The use of nanoencapsulation may provide protection and preserve the physicochemical characteristics of AA for extended periods of time, decreasing losses due to environmental factors. Method: This study evaluated the protective effect of nanoencapsulation in polymeric nanoparticles (chitosan and polycaprolactone) against AA degradation. Evaluation was made of the physicochemical stability of the nanoformulations over time, as well as the toxicological effects in zebrafish (Danio rerio), considering behavior, development, and enzymatic activity. For the statistical tests, ANOVA (two-way, significance of p < 0.05) was used. Results: Both nanoparticle formulations showed high encapsulation efficiency and good physicochemical stability during 90 days. Chitosan (CS) and polycaprolactone (PCL) nanoparticles loaded with AA had mean diameters of 314 and 303 nm and polydispersity indexes of 0.36 and 0.28, respectively. Both nanosystems provided protection against degradation of AA exposed to an oxidizing agent, compared to plain AA. Total degradation of AA was observed after 7, 20, and 480 min for plain AA, the CS nanoparticle formulation, and the PCL nanoparticle formulation, respectively. For zebrafish larvae, the LC50 values were 330.7, 57.4, and 179.6 mg/L for plain AA, the CS nanoparticle formulation, and the PCL nanoparticle formulation, respectively. In toxicity assays using AA at a concentration of 50 mg/L, both types of nanoparticles loaded with AA showed lower toxicity towards the development of the zebrafish, compared to plain AA at the same concentration. Although decreased activity of the enzyme acetylcholinesterase (AChE) did not affect the swimming behavior of zebrafish larvae in the groups evaluated, it may have been associated with the observed morphometric changes, such as curvature of the tail. Conclusions: This study showed that the use of nanosystems is promising for fish nutritional supplementation in aquaculture. In particular, PCL nanoparticles loaded with AA seemed to be most promising, due to higher protection against AA degradation, as well as lower toxicity to zebrafish, compared to the chitosan nanoparticles. The use of nanotechnology opens new perspectives for aquaculture, enabling the reduction of feed nutrient losses, leading to faster fish growth and improved sustainability of this activity. MenosAbstract: Background: Ascorbic acid (AA) is a micronutrient essential for the mechanisms of reproduction, growth, and defense in fish. However, the biosynthesis of this micronutrient does not occur in fish, so it must be supplied with food. A difficulty is that plain AA is unstable, due to the effects of light, high temperature, and oxygen, among others. The use of nanoencapsulation may provide protection and preserve the physicochemical characteristics of AA for extended periods of time, decreasing losses due to environmental factors. Method: This study evaluated the protective effect of nanoencapsulation in polymeric nanoparticles (chitosan and polycaprolactone) against AA degradation. Evaluation was made of the physicochemical stability of the nanoformulations over time, as well as the toxicological effects in zebrafish (Danio rerio), considering behavior, development, and enzymatic activity. For the statistical tests, ANOVA (two-way, significance of p < 0.05) was used. Results: Both nanoparticle formulations showed high encapsulation efficiency and good physicochemical stability during 90 days. Chitosan (CS) and polycaprolactone (PCL) nanoparticles loaded with AA had mean diameters of 314 and 303 nm and polydispersity indexes of 0.36 and 0.28, respectively. Both nanosystems provided protection against degradation of AA exposed to an oxidizing agent, compared to plain AA. Total degradation of AA was observed after 7, 20, and 480 min for plain AA, the CS nanoparticle formu... Mostrar Tudo |
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Palavras-Chave: |
Nanoencapsulação; Nanopartículas de quitosana; Polycaprolactone nanoparticles; Zebrafish. |
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Thesagro: |
Aquicultura; Peixe de Água Doce; Toxidez; Vitamina C. |
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Thesaurus NAL: |
Ascorbic acid; Chitosan; Danio rerio; Nanoparticles; Toxicity; Vitamin supplements. |
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Categoria do assunto: |
W Química e Física |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/225347/1/Vallim-Ecotoxicity-evaluation-2021.pdf
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Marc: |
LEADER 03930naa a2200409 a 4500
001 2133729
005 2021-12-28
008 2021 bl uuuu u00u1 u #d
022 $a1477-3155
024 7 $ahttps://doi.org/10.1186/s12951-021-00910-8$2DOI
100 1 $aLUIS, A. I. S.
245 $aEcotoxicity evaluation of polymeric nanoparticles loaded with ascorbic acid for fish nutrition in aquaculture.$h[electronic resource]
260 $c2021
300 $ap. 1-22.
520 $aAbstract: Background: Ascorbic acid (AA) is a micronutrient essential for the mechanisms of reproduction, growth, and defense in fish. However, the biosynthesis of this micronutrient does not occur in fish, so it must be supplied with food. A difficulty is that plain AA is unstable, due to the effects of light, high temperature, and oxygen, among others. The use of nanoencapsulation may provide protection and preserve the physicochemical characteristics of AA for extended periods of time, decreasing losses due to environmental factors. Method: This study evaluated the protective effect of nanoencapsulation in polymeric nanoparticles (chitosan and polycaprolactone) against AA degradation. Evaluation was made of the physicochemical stability of the nanoformulations over time, as well as the toxicological effects in zebrafish (Danio rerio), considering behavior, development, and enzymatic activity. For the statistical tests, ANOVA (two-way, significance of p < 0.05) was used. Results: Both nanoparticle formulations showed high encapsulation efficiency and good physicochemical stability during 90 days. Chitosan (CS) and polycaprolactone (PCL) nanoparticles loaded with AA had mean diameters of 314 and 303 nm and polydispersity indexes of 0.36 and 0.28, respectively. Both nanosystems provided protection against degradation of AA exposed to an oxidizing agent, compared to plain AA. Total degradation of AA was observed after 7, 20, and 480 min for plain AA, the CS nanoparticle formulation, and the PCL nanoparticle formulation, respectively. For zebrafish larvae, the LC50 values were 330.7, 57.4, and 179.6 mg/L for plain AA, the CS nanoparticle formulation, and the PCL nanoparticle formulation, respectively. In toxicity assays using AA at a concentration of 50 mg/L, both types of nanoparticles loaded with AA showed lower toxicity towards the development of the zebrafish, compared to plain AA at the same concentration. Although decreased activity of the enzyme acetylcholinesterase (AChE) did not affect the swimming behavior of zebrafish larvae in the groups evaluated, it may have been associated with the observed morphometric changes, such as curvature of the tail. Conclusions: This study showed that the use of nanosystems is promising for fish nutritional supplementation in aquaculture. In particular, PCL nanoparticles loaded with AA seemed to be most promising, due to higher protection against AA degradation, as well as lower toxicity to zebrafish, compared to the chitosan nanoparticles. The use of nanotechnology opens new perspectives for aquaculture, enabling the reduction of feed nutrient losses, leading to faster fish growth and improved sustainability of this activity.
650 $aAscorbic acid
650 $aChitosan
650 $aDanio rerio
650 $aNanoparticles
650 $aToxicity
650 $aVitamin supplements
650 $aAquicultura
650 $aPeixe de Água Doce
650 $aToxidez
650 $aVitamina C
653 $aNanoencapsulação
653 $aNanopartículas de quitosana
653 $aPolycaprolactone nanoparticles
653 $aZebrafish
700 1 $aCAMPOS, E. V. R.
700 1 $aOLIVEIRA, J. L. de
700 1 $aVALLIM, J. H.
700 1 $aPROENÇA, P. L. de F.
700 1 $aCASTANHA, R. F.
700 1 $aCASTRO, V. L. S. S. de
700 1 $aFRACETO, L. F.
773 $tJournal of Nanobiotechnology$gv. 19, n. 1, article 163, 2021.
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Embrapa Meio Ambiente (CNPMA) |
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