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Registro Completo |
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Biblioteca(s): |
Embrapa Pantanal. |
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Data corrente: |
12/07/1996 |
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Data da última atualização: |
12/07/1996 |
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Autoria: |
GERKEN, S. E.; MOTA-SANTOS, T.A.; VAZ, N. M.; CORREA-OLIVEIRA, R.; SILVA, W. D. da; GAZZINELLI, G. |
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Título: |
Recovery of schistosomula of Schistosoma mansoni from mouse skin: involvement of mast cells and vasoactive amines. |
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Ano de publicação: |
1984 |
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Fonte/Imprenta: |
Brazilian Journal of Medical and Biological Research, v.17, p.301-307, 1984. |
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Idioma: |
Inglês |
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Conteúdo: |
1. Normal and S. mansoni-infected mice were exposed to the penetration of 250-350 cercariae through one ear .Two days later, when the ear was removed and chopped, 30 to 50% more schistosomula were recovered from the ears of normal mice than from the ears of infected (immune ) mice.
2. Administration of cyproheptadine, a histamine-serotonin antagonist (2 mg/kg), 30 min
before challenge infection rendered immune mice indistinguishable from normal rnice.
3. Partial depletion of histamine by pretreatment with compound 48-80, a histarnime releaser (1 mg/kg) 2 days before challenge infection increased the numbers of schistosomula recovered from the ears of both normal and immune mice.
4. These results are interpreted to mean that vasoactive amines released by skin mast cells play an important role in hindering the viable passage of schistosomula through the skin of normal and immune mice.
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Palavras-Chave: |
Acquired resistance; Celula de mastro; Mast cell; Mouse skin; Pele de rato; Resistencia adquerida. |
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Thesagro: |
Imunidade; Schistosoma Mansoni. |
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Thesaurus Nal: |
anaphylaxis; cyproheptadine; immunity. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 01811naa a2200313 a 4500
001 1789401
005 1996-07-12
008 1984 bl --- 0-- u #d
100 1 $aGERKEN, S. E.
245 $aRecovery of schistosomula of Schistosoma mansoni from mouse skin$binvolvement of mast cells and vasoactive amines.
260 $c1984
520 $a1. Normal and S. mansoni-infected mice were exposed to the penetration of 250-350 cercariae through one ear .Two days later, when the ear was removed and chopped, 30 to 50% more schistosomula were recovered from the ears of normal mice than from the ears of infected (immune ) mice. 2. Administration of cyproheptadine, a histamine-serotonin antagonist (2 mg/kg), 30 min before challenge infection rendered immune mice indistinguishable from normal rnice. 3. Partial depletion of histamine by pretreatment with compound 48-80, a histarnime releaser (1 mg/kg) 2 days before challenge infection increased the numbers of schistosomula recovered from the ears of both normal and immune mice. 4. These results are interpreted to mean that vasoactive amines released by skin mast cells play an important role in hindering the viable passage of schistosomula through the skin of normal and immune mice.
650 $aanaphylaxis
650 $acyproheptadine
650 $aimmunity
650 $aImunidade
650 $aSchistosoma Mansoni
653 $aAcquired resistance
653 $aCelula de mastro
653 $aMast cell
653 $aMouse skin
653 $aPele de rato
653 $aResistencia adquerida
700 1 $aMOTA-SANTOS, T.A.
700 1 $aVAZ, N. M.
700 1 $aCORREA-OLIVEIRA, R.
700 1 $aSILVA, W. D. da
700 1 $aGAZZINELLI, G.
773 $tBrazilian Journal of Medical and Biological Research$gv.17, p.301-307, 1984.
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Registro original: |
Embrapa Pantanal (CPAP) |
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| Registros recuperados : 1 | |
| 1. |  | SILVA, L. G. de O.; HOOGERHEIDE, E. S. S.; ROSSI, A. A. B.; BOTELHO, S. de C. C.; SILVA, B. R. da; SILVA, W. D. da. Caracterização biométrica de quiabo-de-metro. In: ENCONTRO DE CIÊNCIA E TECNOLOGIAS AGROSSUSTENTÁVEIS, 5.; JORNADA CIENTÍFICA DA EMBRAPA AGROSSILVIPASTORIL, 10., 2021. Sinop. Resumos... Brasília, DF: Embrapa, 2021. p. 14.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Agrossilvipastoril. |
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| Registros recuperados : 1 | |
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