|
|
Registro Completo |
Biblioteca(s): |
Embrapa Agricultura Digital. |
Data corrente: |
06/11/2020 |
Data da última atualização: |
06/11/2020 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
LEMOS, M. P. L.; SARAIVA, M. M. S.; LEITE, E. L.; SILVA, N. M. V.; VASCONCELOS, P. C.; GIACHETTO, P. F.; FREITAS NETO, O. C.; GIVISIEZ, P. E. N.; GEBREYES, W. A.; OLIVEIRA, C. J. B. |
Afiliação: |
MATEUS P. L. LEMOS, CCA/UFPB; MAURO M. S. SARAIVA, CCA/UFPB; ELMA L. LEITE, CCA/UFPB; NÚBIA M. V. SILVA, CCA/UFPB; PRISCYLLA C. VASCONCELOS, CCA/UFPB; POLIANA FERNANDA GIACHETTO, CNPTIA; OLIVEIRO C. FREITAS NETO, UFMG; PATRÍCIA E. N. GIVISIEZ, CCA/UFPB; WONDWOSSEN A. GEBREYES, The Ohio State University, Columbus; CELSO J. B. OLIVEIRA, CCA/UFPB, The Ohio State University, Columbus. |
Título: |
The posthatch prophylactic use of ceftiofur affects the cecalmicrobiota similar to the dietary sanguinarine supplementation in broilers. |
Ano de publicação: |
2020 |
Fonte/Imprenta: |
Poultry Science, v. 99, n. 11, p. 6013-6021, Nov. 2020. |
DOI: |
https://doi.org/10.1016/j.psj.2020.06.078 |
Idioma: |
Inglês |
Conteúdo: |
Abstract. The prophylactic administration of ceftiofur to newly hatched chicks is a common practice in some hatcheries worldwide to mitigate early gastrointestinal infections caused by Enterobacteriaceae. In spite of the crucial role of the gut microbiome for the broiler's health, there is still limited information on how the microbial composition is affected by such procedure. We investigated the effects of posthatch prophylactic application of ceftiofur on the cecal microbiota of 14-day-old broilers fed regular or sanguinarine-supplemented diets. DNA samples were extracted from cecal contents, amplified for the V3-V4 regions of the microbial 16S rRNA gene, and sequenced in a high-throughput sequencing platform (Illumina MiSeq). After downstream bioinformatics and statistical analyses, our results demonstrated that both ceftiofur and sanguinarine treatments similarly increased the proportions of the phylum Bacteroidetes and the genera Bacteroides and Megamonas, whereas reduced the relative abundances of Firmicutes and Lachnospiraceae in the ceca of the birds. Such changes are probably associated with increased carbohydrate fermentation processes favoring the production of short-chain fatty acids. This was also corroborated by the functional prediction findings, which suggest an increase in some metabolic pathways associated with digestibility in broilers receiving ceftiofur. Considering that antimicrobial stewardship in animal production systems is strongly needed to mitigate the threat of antimicrobial resistance, our findings show that supplementation with a phytogenic feed additive can lead to a similar microbial composition in the ceca of commercial broiler chickens, suggesting that the use of alternative products could lead to functional modifications without increasing pressure for antimicrobial resistance. MenosAbstract. The prophylactic administration of ceftiofur to newly hatched chicks is a common practice in some hatcheries worldwide to mitigate early gastrointestinal infections caused by Enterobacteriaceae. In spite of the crucial role of the gut microbiome for the broiler's health, there is still limited information on how the microbial composition is affected by such procedure. We investigated the effects of posthatch prophylactic application of ceftiofur on the cecal microbiota of 14-day-old broilers fed regular or sanguinarine-supplemented diets. DNA samples were extracted from cecal contents, amplified for the V3-V4 regions of the microbial 16S rRNA gene, and sequenced in a high-throughput sequencing platform (Illumina MiSeq). After downstream bioinformatics and statistical analyses, our results demonstrated that both ceftiofur and sanguinarine treatments similarly increased the proportions of the phylum Bacteroidetes and the genera Bacteroides and Megamonas, whereas reduced the relative abundances of Firmicutes and Lachnospiraceae in the ceca of the birds. Such changes are probably associated with increased carbohydrate fermentation processes favoring the production of short-chain fatty acids. This was also corroborated by the functional prediction findings, which suggest an increase in some metabolic pathways associated with digestibility in broilers receiving ceftiofur. Considering that antimicrobial stewardship in animal production systems is strongly needed to mitiga... Mostrar Tudo |
Palavras-Chave: |
16S rRNA; Aplicação profilática pós-parto; Bioinformática; Broiler; Cecal microbiota. |
Thesagro: |
Análise Estatística; Frango; Frango de Corte. |
Thesaurus Nal: |
Bioinformatics; Broiler chickens; Ceftiofur; Sanguinarine; Statistical analysis. |
Categoria do assunto: |
-- |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/217539/1/AP-Posthatch-prophylactic-2020.pdf
|
Marc: |
LEADER 03064naa a2200397 a 4500 001 2126346 005 2020-11-06 008 2020 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.1016/j.psj.2020.06.078$2DOI 100 1 $aLEMOS, M. P. L. 245 $aThe posthatch prophylactic use of ceftiofur affects the cecalmicrobiota similar to the dietary sanguinarine supplementation in broilers.$h[electronic resource] 260 $c2020 520 $aAbstract. The prophylactic administration of ceftiofur to newly hatched chicks is a common practice in some hatcheries worldwide to mitigate early gastrointestinal infections caused by Enterobacteriaceae. In spite of the crucial role of the gut microbiome for the broiler's health, there is still limited information on how the microbial composition is affected by such procedure. We investigated the effects of posthatch prophylactic application of ceftiofur on the cecal microbiota of 14-day-old broilers fed regular or sanguinarine-supplemented diets. DNA samples were extracted from cecal contents, amplified for the V3-V4 regions of the microbial 16S rRNA gene, and sequenced in a high-throughput sequencing platform (Illumina MiSeq). After downstream bioinformatics and statistical analyses, our results demonstrated that both ceftiofur and sanguinarine treatments similarly increased the proportions of the phylum Bacteroidetes and the genera Bacteroides and Megamonas, whereas reduced the relative abundances of Firmicutes and Lachnospiraceae in the ceca of the birds. Such changes are probably associated with increased carbohydrate fermentation processes favoring the production of short-chain fatty acids. This was also corroborated by the functional prediction findings, which suggest an increase in some metabolic pathways associated with digestibility in broilers receiving ceftiofur. Considering that antimicrobial stewardship in animal production systems is strongly needed to mitigate the threat of antimicrobial resistance, our findings show that supplementation with a phytogenic feed additive can lead to a similar microbial composition in the ceca of commercial broiler chickens, suggesting that the use of alternative products could lead to functional modifications without increasing pressure for antimicrobial resistance. 650 $aBioinformatics 650 $aBroiler chickens 650 $aCeftiofur 650 $aSanguinarine 650 $aStatistical analysis 650 $aAnálise Estatística 650 $aFrango 650 $aFrango de Corte 653 $a16S rRNA 653 $aAplicação profilática pós-parto 653 $aBioinformática 653 $aBroiler 653 $aCecal microbiota 700 1 $aSARAIVA, M. M. S. 700 1 $aLEITE, E. L. 700 1 $aSILVA, N. M. V. 700 1 $aVASCONCELOS, P. C. 700 1 $aGIACHETTO, P. F. 700 1 $aFREITAS NETO, O. C. 700 1 $aGIVISIEZ, P. E. N. 700 1 $aGEBREYES, W. A. 700 1 $aOLIVEIRA, C. J. B. 773 $tPoultry Science$gv. 99, n. 11, p. 6013-6021, Nov. 2020.
Download
Esconder MarcMostrar Marc Completo |
Registro original: |
Embrapa Agricultura Digital (CNPTIA) |
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
Registros recuperados : 2 | |
1. | | LEMOS, M. P. L.; SARAIVA, M. M. S.; LEITE, E. L.; SILVA, N. M. V.; VASCONCELOS, P. C.; GIACHETTO, P. F.; FREITAS NETO, O. C.; GIVISIEZ, P. E. N.; GEBREYES, W. A.; OLIVEIRA, C. J. B. The posthatch prophylactic use of ceftiofur affects the cecalmicrobiota similar to the dietary sanguinarine supplementation in broilers. Poultry Science, v. 99, n. 11, p. 6013-6021, Nov. 2020.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Agricultura Digital. |
| |
2. | | ROLIM, F. R. L.; OLIVEIRA, C. J. B.; FREITAS NETO, O. C. de; SANTOS, K. M. O. dos; GUERRA, G. C. B.; RODRIGUES, R. V.; ASSIS, P. O. A. de; ARAUJO, D. F. de S.; CARVALHO, V. A. G. de; LEMOS, M. L. P.; SILVA, N. M. V. da; SOARES, J. K.; GARCIA, H. E. M.; SOUZA, E. L. de; SOUZA, F. de A. L.; BARROS, M. E. G.; OLIVEIRA, M. E. G.; QUEIROGA, R. C. R. E. Microbiological, immunological, and histological changes in the gut of Salmonella Enteritidis-challenged rats fed goat cheese containing Lactobacillus rhamnosus EM1107. Journal of Dairy Science, v. 104, n. 1, p. 179-197, 2021.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Agroindústria de Alimentos. |
| |
Registros recuperados : 2 | |
|
Nenhum registro encontrado para a expressão de busca informada. |
|
|