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Registro Completo |
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Biblioteca(s): |
Embrapa Rondônia. |
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Data corrente: |
14/08/2013 |
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Data da última atualização: |
14/08/2013 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
AKBAR, H.; SCHMITT, E.; BALLOU, M. A.; CORRÊA, M. N.; DEPETERS, E. J.; LOOR, J. J. |
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Afiliação: |
haji Akbar, University of illinois, Urbana; EDUARDO SCHMITT, CPAF-RO; Michael A. Ballou, Texas Tech University; Marcio N. Corrêa, NUPeeC, UFPel; Edward J. DePeter, University of California; Juan J. Loor, University of illinois, Urbana. |
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Título: |
Dietary Lipid During Late-pregnancy and early-Lactation to Manipulate Metabolic and Inflammatory Gene Network Expression in Dairy Cattle Liver with a Focus on PPARs. |
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Ano de publicação: |
2013 |
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Fonte/Imprenta: |
Gene Regulation and Systems Biology, v. 7, p. 103?123, 2013. |
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Idioma: |
Inglês |
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Conteúdo: |
Polyunsaturated (PUFA) long-chain fatty acids (LCFAs) are more potent in eliciting molecular and tissue functional changes in monogastrics than saturated LCFA. From −21 through 10 days relative to parturition dairy cows were fed no supplemental LCFA (control), saturated LCFA (SFAT; mainly 16:0 and 18:0), or fish oil (FISH; high-PUFA). Twenty-seven genes were measured via quantitative RT-PCR in liver tissue on day −14 and day 10. Expression of nuclear receptor co-activators (CARM1, MED1), LCFA metabolism (ACSL1, SCD, ACOX1), and inflammation (IL6, TBK1, IKBKE) genes was lower with SFAT than control on day −14. Expression of SCD, however, was markedly lower with FISH than control or SFAT on both −14 and 10 days. FISH led to further decreases in expression on day 10 of LCFA metabolism (CD36, PLIN2, ACSL1, ACOX1), intracellular energy (UCP2, STK11, PRKAA1), de novo cholesterol synthesis (SREBF2), inflammation (IL6, TBK1, IKBKE), and nuclear receptor signaling genes (PPARD, MED1, NRIP1). No change in expression was observed for PPARA and RXRA. The increase of DGAT2, PLIN2, ACSL1, and ACOX1 on day 10 versus −14 in cows fed SFAT suggested upregulation of both beta-oxidation and lipid droplet (LD) formation. However, liver triacylglycerol concentration was similar among treatments. The hepatokine FGF21 and the gluconeogenic genes PC and PCK1 increased markedly on day 10 versus −14 only in controls. At the levels supplemented, the change in the profile of metabolic genes after parturition in cows fed saturated fat suggested a greater capacity for uptake of fatty acids and intracellular handling without excessive storage of LD. MenosPolyunsaturated (PUFA) long-chain fatty acids (LCFAs) are more potent in eliciting molecular and tissue functional changes in monogastrics than saturated LCFA. From −21 through 10 days relative to parturition dairy cows were fed no supplemental LCFA (control), saturated LCFA (SFAT; mainly 16:0 and 18:0), or fish oil (FISH; high-PUFA). Twenty-seven genes were measured via quantitative RT-PCR in liver tissue on day −14 and day 10. Expression of nuclear receptor co-activators (CARM1, MED1), LCFA metabolism (ACSL1, SCD, ACOX1), and inflammation (IL6, TBK1, IKBKE) genes was lower with SFAT than control on day −14. Expression of SCD, however, was markedly lower with FISH than control or SFAT on both −14 and 10 days. FISH led to further decreases in expression on day 10 of LCFA metabolism (CD36, PLIN2, ACSL1, ACOX1), intracellular energy (UCP2, STK11, PRKAA1), de novo cholesterol synthesis (SREBF2), inflammation (IL6, TBK1, IKBKE), and nuclear receptor signaling genes (PPARD, MED1, NRIP1). No change in expression was observed for PPARA and RXRA. The increase of DGAT2, PLIN2, ACSL1, and ACOX1 on day 10 versus −14 in cows fed SFAT suggested upregulation of both beta-oxidation and lipid droplet (LD) formation. However, liver triacylglycerol concentration was similar among treatments. The hepatokine FGF21 and the gluconeogenic genes PC and PCK1 increased markedly on day 10 versus −14 only in controls. At the levels supplemented, the change in the pro... Mostrar Tudo |
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Palavras-Chave: |
Fat supplementation; Hepatic gene network; Rede de gene hepática; Suplementação de gordura; Vacas leiteiras. |
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Thesaurus Nal: |
dairy cows. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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Marc: |
LEADER 02512naa a2200253 a 4500
001 1964101
005 2013-08-14
008 2013 bl uuuu u00u1 u #d
100 1 $aAKBAR, H.
245 $aDietary Lipid During Late-pregnancy and early-Lactation to Manipulate Metabolic and Inflammatory Gene Network Expression in Dairy Cattle Liver with a Focus on PPARs.$h[electronic resource]
260 $c2013
520 $aPolyunsaturated (PUFA) long-chain fatty acids (LCFAs) are more potent in eliciting molecular and tissue functional changes in monogastrics than saturated LCFA. From −21 through 10 days relative to parturition dairy cows were fed no supplemental LCFA (control), saturated LCFA (SFAT; mainly 16:0 and 18:0), or fish oil (FISH; high-PUFA). Twenty-seven genes were measured via quantitative RT-PCR in liver tissue on day −14 and day 10. Expression of nuclear receptor co-activators (CARM1, MED1), LCFA metabolism (ACSL1, SCD, ACOX1), and inflammation (IL6, TBK1, IKBKE) genes was lower with SFAT than control on day −14. Expression of SCD, however, was markedly lower with FISH than control or SFAT on both −14 and 10 days. FISH led to further decreases in expression on day 10 of LCFA metabolism (CD36, PLIN2, ACSL1, ACOX1), intracellular energy (UCP2, STK11, PRKAA1), de novo cholesterol synthesis (SREBF2), inflammation (IL6, TBK1, IKBKE), and nuclear receptor signaling genes (PPARD, MED1, NRIP1). No change in expression was observed for PPARA and RXRA. The increase of DGAT2, PLIN2, ACSL1, and ACOX1 on day 10 versus −14 in cows fed SFAT suggested upregulation of both beta-oxidation and lipid droplet (LD) formation. However, liver triacylglycerol concentration was similar among treatments. The hepatokine FGF21 and the gluconeogenic genes PC and PCK1 increased markedly on day 10 versus −14 only in controls. At the levels supplemented, the change in the profile of metabolic genes after parturition in cows fed saturated fat suggested a greater capacity for uptake of fatty acids and intracellular handling without excessive storage of LD.
650 $adairy cows
653 $aFat supplementation
653 $aHepatic gene network
653 $aRede de gene hepática
653 $aSuplementação de gordura
653 $aVacas leiteiras
700 1 $aSCHMITT, E.
700 1 $aBALLOU, M. A.
700 1 $aCORRÊA, M. N.
700 1 $aDEPETERS, E. J.
700 1 $aLOOR, J. J.
773 $tGene Regulation and Systems Biology$gv. 7, p. 103?123, 2013.
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Registro original: |
Embrapa Rondônia (CPAF-RO) |
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Biblioteca |
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Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
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Registro Completo
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Biblioteca(s): |
Embrapa Amazônia Ocidental; Embrapa Meio Ambiente; Embrapa Pesca e Aquicultura; Embrapa Semiárido. |
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Data corrente: |
26/05/2020 |
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Data da última atualização: |
06/01/2021 |
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Tipo da produção científica: |
Capítulo em Livro Técnico-Científico |
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Autoria: |
WANDELLI, E. V.; ABREU, L. S. de; TAVARES, E. D.; BIANCHINI, F.; SILVA, A. P. da; BELTRAO, S. L. L.; FERREIRA, M. do S. G. |
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Afiliação: |
ELISA VIEIRA WANDELLI, CPAA; LUCIMAR SANTIAGO DE ABREU, CNPMA; EDSON DIOGO TAVARES, CPATC; FABRICIO BIANCHINI, CPATSA; ADRIANO PRYSTHON DA SILVA, CNPASA; SELMA LUCIA LIRA BELTRAO, SIN; MARIA DO SOCORRO GONCALVES FERREIRA, CPATU. |
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Título: |
Contributions of Embrapa to poverty eradication. |
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Ano de publicação: |
2020 |
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Fonte/Imprenta: |
In: COSTA, P. da; COSTA, J. R. da; WANDELLI, E. V.; BIANCHINI, F.; TAVARES, E. D. (Ed.). No poverty: contributions of Embrapa. Brasília, DF: Embrapa, 2020. |
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Páginas: |
p. 27-37. |
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Série: |
(Sustainable Development Goals, 1). |
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ISBN: |
978-65-86056-03-7 |
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Idioma: |
Inglês
Português |
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Conteúdo: |
This chapter presents solutions related to the sustainable agrifood systems developed by Embrapa that contribute to the following targets of the Sustainable Development Goal 1 (SDG 1) (United Nations, 2018): Target 1.1) "By 2030, eradicate extreme poverty for all people everywhere, currently measured as people living on less than $1.25 a day"; and target 1.2) "By 2030, reduce at least by half the proportion of men, women and children of all ages living in poverty in all its dimensions according to national definitions. |
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Palavras-Chave: |
Embrapa; Eradicação da pobreza; Sistema agroalimentare sustentável. |
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Thesagro: |
Desenvolvimento Sustentável; Pobreza; Políticas Públicas; Segurança Alimentar. |
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Thesaurus NAL: |
Poverty; Rural communities; Rural development; Rural population; Rural poverty. |
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Categoria do assunto: |
B Sociologia Rural |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/214738/1/Contributions-of-Embrapa-2020.pdf
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Marc: |
LEADER 01700naa a2200373 a 4500
001 2129038
005 2021-01-06
008 2020 bl uuuu u00u1 u #d
020 $a978-65-86056-03-7
100 1 $aWANDELLI, E. V.
245 $aContributions of Embrapa to poverty eradication.$h[electronic resource]
260 $c2020
300 $ap. 27-37.
490 $a(Sustainable Development Goals, 1).
520 $aThis chapter presents solutions related to the sustainable agrifood systems developed by Embrapa that contribute to the following targets of the Sustainable Development Goal 1 (SDG 1) (United Nations, 2018): Target 1.1) "By 2030, eradicate extreme poverty for all people everywhere, currently measured as people living on less than $1.25 a day"; and target 1.2) "By 2030, reduce at least by half the proportion of men, women and children of all ages living in poverty in all its dimensions according to national definitions.
650 $aPoverty
650 $aRural communities
650 $aRural development
650 $aRural population
650 $aRural poverty
650 $aDesenvolvimento Sustentável
650 $aPobreza
650 $aPolíticas Públicas
650 $aSegurança Alimentar
653 $aEmbrapa
653 $aEradicação da pobreza
653 $aSistema agroalimentare sustentável
700 1 $aABREU, L. S. de
700 1 $aTAVARES, E. D.
700 1 $aBIANCHINI, F.
700 1 $aSILVA, A. P. da
700 1 $aBELTRAO, S. L. L.
700 1 $aFERREIRA, M. do S. G.
773 $tIn: COSTA, P. da; COSTA, J. R. da; WANDELLI, E. V.; BIANCHINI, F.; TAVARES, E. D. (Ed.). No poverty: contributions of Embrapa. Brasília, DF: Embrapa, 2020.
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Embrapa Amazônia Ocidental (CPAA) |
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