Data/hora: 11/06/2024 22:24:03

Biblioteca(s): | Embrapa Meio Ambiente.
Data corrente: | 02/08/2017
Data da última atualização: | 09/08/2021
Autoria: | SCHINKE, C.; MARTINS, T.; QUEIROZ, S. C. do N. de; MELO, I. S. de; REYES, F. G. R.
Afiliação: | CLAUDIA SCHINKE, FEA-UNICAMP; THAMIRES MARTINS, FEA-UNICAMP; SONIA CLAUDIA DO N DE QUEIROZ, CNPMA; ITAMAR SOARES DE MELO, CNPMA; FELIX GUILLERMO REYES REYES, FEA-UNICAMP.
Título: | Antibacterial compounds from marine bacteria, 2010-2015.
Ano de publicação: | 2017
Fonte/Imprenta: | Journal of Natural Products, Cincinnati, v. 80, n. 4, p. 1215?1228, 2017.
DOI: | http://dx.doi.org/10.1021/acs.jnatprod.6b00235
Idioma: | Inglês
Conteúdo: | This review summarizes the reports on antibacterial compounds that have been obtained from marine-derived bacteria during the period 2010?2015. Over 50 active compounds were isolated during this period, most of which (69%) were obtained from Actinobacteria. Several compounds were already known, such as etamycin A (11) and nosiheptide (65), and new experiments with them showed some previously undetected antibacterial activities, highlighting the fact that known natural products may be an important source of new antibacterial leads. New broad-spectrum antibacterial compounds were reported with activity against antibiotic resistant Gram-positive and Gram-negative bacteria. Anthracimycin (33), kocurin (66), gageotetrins A?C(72?74), and gageomacrolactins 1?3(86?88) are examples of compounds that display promising properties and could be leads to new antibiotics. A number of microbes produced mixtures of metabolites sharing similar chemical sca?olds, and structure?activity relationships are discussed.
Palavras-Chave: | Agente antimicrobiano; Bactéria marinha.
Thesagro: | Actinomiceto; Bactéria.
Categoria do assunto: | S Ciências Biológicas
Registro original: | Embrapa Meio Ambiente (CNPMA)
Exemplares: | CNPMA - (15552-1) - UPC - AP - DD -  -  -  - DIS