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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
01/08/1992 |
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Data da última atualização: |
02/01/2024 |
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Autoria: |
HEGARTY, M. P.; SCHINCKEL, P. G.; COURT, R. D. |
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Título: |
Reaction of sheep to the consumption of Leucaena glauca Benth. and to its toxic principle mimosine. |
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Ano de publicação: |
1964 |
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Fonte/Imprenta: |
Australian Journal of Agricultural Research, v. 15, n. 1, p. 153-167, 1964. |
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DOI: |
https://doi.org/10.1071/AR9640153 |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: Sheep on a sole diet of Leucaena glauca Benth. shed their fleece. The amino acid mimosine has been shown to be the depilatory agent. The depilatory effect of L. glauca was influenced by level and method of feeding. Small quantities of mimosine were excreted by sheep consuming L. glauca, but the major metabolite in the urine was identified as 3,4-dihydroxypyridine (DHP). It was established from the results of intravenous, intra-abomasal, and intraruminal administration of mimosine that sheep cannot detoxicate mimosine after absorption, but extensive degradation of mimosine to DHP takes place in the rumen. The absence of toxic symptoms in a sheep conditioned to L. glauca appeared to be due to increased detoxication in the rumen rather than to the development of an adaptive tolerance after absorption.
The histological changes in the skin are described, and reasons for conflicting reports on the toxicity of L. glauca are discussed. A simple method for the isolation of mimosine from the seed of L. glauca is described in the Appendix. |
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Palavras-Chave: |
Acacia glauca; Techniques. |
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Thesagro: |
Doença; Intoxicação; Leucaena Leucocephala; Mimosa; Ovelha; Ovino; Planta Tóxica; Rúmen. |
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Thesaurus Nal: |
Degradation; Methodology; Mimosine; Ruminant nutrition; Sheep feeding; Toxicity. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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Marc: |
LEADER 02013naa a2200349 a 4500
001 1523093
005 2024-01-02
008 1964 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1071/AR9640153$2DOI
100 1 $aHEGARTY, M. P.
245 $aReaction of sheep to the consumption of Leucaena glauca Benth. and to its toxic principle mimosine.
260 $c1964
520 $aAbstract: Sheep on a sole diet of Leucaena glauca Benth. shed their fleece. The amino acid mimosine has been shown to be the depilatory agent. The depilatory effect of L. glauca was influenced by level and method of feeding. Small quantities of mimosine were excreted by sheep consuming L. glauca, but the major metabolite in the urine was identified as 3,4-dihydroxypyridine (DHP). It was established from the results of intravenous, intra-abomasal, and intraruminal administration of mimosine that sheep cannot detoxicate mimosine after absorption, but extensive degradation of mimosine to DHP takes place in the rumen. The absence of toxic symptoms in a sheep conditioned to L. glauca appeared to be due to increased detoxication in the rumen rather than to the development of an adaptive tolerance after absorption. The histological changes in the skin are described, and reasons for conflicting reports on the toxicity of L. glauca are discussed. A simple method for the isolation of mimosine from the seed of L. glauca is described in the Appendix.
650 $aDegradation
650 $aMethodology
650 $aMimosine
650 $aRuminant nutrition
650 $aSheep feeding
650 $aToxicity
650 $aDoença
650 $aIntoxicação
650 $aLeucaena Leucocephala
650 $aMimosa
650 $aOvelha
650 $aOvino
650 $aPlanta Tóxica
650 $aRúmen
653 $aAcacia glauca
653 $aTechniques
700 1 $aSCHINCKEL, P. G.
700 1 $aCOURT, R. D.
773 $tAustralian Journal of Agricultural Research$gv. 15, n. 1, p. 153-167, 1964.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
