Data/hora: 12/06/2024 06:10:36

Biblioteca(s): 	Embrapa Gado de Leite.	
Data corrente: 	18/01/2023	
Data da última atualização: 	11/04/2023	
Autoria: 	GARCIA, A. O.; OTTO, P. I.; GLATZL JUNIOR, L. A.; ROCHA, R. de F. B.; SANTOS, M. G. dos; OLIVEIRA, D. A. de; SILVA, M. V. G. B.; PANETTO, J. C. do C.; MACHADO, M. A.; VERNEQUE, R. da S.; GUIMARÃES, S. E. F.	
Afiliação: 	ARIELLY OLIVEIRA GARCIA, Universidade Federal de Viçosa; PAMELA ITAJARA OTTO, Universidade Federal de Santa Maria; LUIZ AFONSO GLATZL JUNIOR, Universidade Federal de Juiz de Fora; RENATA DE FÁTIMA BRETANHA ROCHA, Universidade Federal de Viçosa; MATEUS GUIMARÃES DOS SANTOS, Universidade Federal de Viçosa; DANIELE ALVES DE OLIVEIRA, Universidade Federal de Santa Maria; MARCOS VINICIUS GUALBERTO B SILVA, CNPGL; JOAO CLAUDIO DO CARMO PANETTO, CNPGL; MARCO ANTONIO MACHADO, CNPGL; RUI DA SILVA VERNEQUE, CNPGL; SIMONE ELIZA FACIONI GUIMARÃES, Universidade Federal de Viçosa.	
Título: 	Pedigree reconstruction and population structure using SNP markers in Gir cattle.	
Ano de publicação: 	2023	
Fonte/Imprenta: 	Journal of Applied Genetics, v. 64, p. 329-340, 2023.	
DOI: 	https://doi.org/10.1007/s13353-023-00747-x	
Idioma: 	Inglês	
Conteúdo: 	Our objective was to establish a SNPs panel for pedigree reconstruction using microarrays of different densities and evaluate the genomic relationship coefficient of the inferred pedigree, in addition to analyzing the population structure based on genomic analyses in Gir cattle. For parentage analysis and genomic relationship, 16,205 genotyped Gir animals (14,458 females and 1747 males) and 1810 common markers to the four SNP microarrays were used. For population structure analyses, including linkage disequilibrium, effective population size, and runs of homozygosity (ROH), genotypes from 21,656 animals were imputed. Likelihood ratio (LR) approach was used to reconstruct the pedigree, deepening the pedigree and showing it is well established in terms of recent information. Coefficients for each relationship category of the inferred pedigree were adequate. Linkage disequilibrium showed rapid decay. We detected a decrease in the effective population size over the last 50 generations, with the average generation interval around 9.08 years. Higher ROH-based inbreeding coefficient in a class of short ROH segments, with moderate to high values, was also detected, suggesting bottlenecks in the Gir genome. Breeding strategies to minimize inbreeding and avoid massive use of few proven sires with high genetic value are suggested to maintain genetic variability in future generations. In addition, we recommend reducing the generation interval to maximize genetic progress and increase effective population size.	
Thesagro: 	Bovino; DNA; Endogamia; Gado Gir; Marcador Genético.	
Categoria do assunto: 	L Ciência Animal e Produtos de Origem Animal	
URL: 	http://ainfo.cnptia.embrapa.br/digital/bitstream/item/248991/1/Pedigree-reconstruction-and-population-structure-using-SNP-markers-in-Gir-cattle.pdf	
Registro original: 	Embrapa Gado de Leite (CNPGL)	
Exemplares: 	CNPGL - (25948-1) - UPC - AP - DD -  -  -  - DIS