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Registro Completo |
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Biblioteca(s): |
Embrapa Gado de Leite. |
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Data corrente: |
05/02/2013 |
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Data da última atualização: |
08/02/2024 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
OTENIO, C. C. M.; FONSECA, I.; MARTINS, M. F.; RIBEIRO, L. C.; ASSIS, N. M. S. P.; FERREIRA, A. P.; RIBEIRO, R. A. |
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Afiliação: |
C. C. M. OTENIO, UFJF; I. FONSECA, UFV; MARTA FONSECA MARTINS, CNPGL; L. C. RIBEIRO, UFV; N. M. S. P. ASSIS, UFJF; A. P. FERREIRA, UFJF; R. A. RIBEIRO, UFJF. |
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Título: |
Expression of IL-1B, IL-6, TNF-a and iNOS in pregnant women with periodontal disease. |
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Ano de publicação: |
2012 |
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Fonte/Imprenta: |
Genetics and Molecular Research, v. 11, n. 4, p. 4468-4478, 2012. |
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DOI: |
https://doi.org/10.4238/2012.september.20.3 |
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Idioma: |
Inglês |
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Conteúdo: |
Periodontal disease is one of the most prevalent oral diseases. An association between this disease and pregnancy has been suggested, but available findings are controversial. We evaluated the expression levels of interleukins (IL-1β and IL-6), tumor necrosis factor-alpha (TNF-α), and inducible nitric oxide synthase (iNOS) in pregnant women with and without periodontal disease in comparison with non-pregnant women with and without periodontal disease since studies have suggested a relationship between periodontitis and the expression levels of these genes. The women in the sample were distributed into four groups: pregnant and non-pregnant women, with or without periodontal disease, a total of 32 women. The periodontal condition was evaluated according to the probing depth, clinical attachment level and bleeding on probing. Analysis of gene expression was performed by real-time PCR. Comparisons were made of the level of gene expression among the four groups. Expression of IL-1β in the non-pregnant women with periodontal disease was 12.6 times higher than in the non-pregnant women without periodontal disease (P < 0.01), while expression of TNF-α in the non-pregnant women without periodontal disease was 3.5 times higher than in the pregnant women with periodontal disease (P < 0.05). Despite these differences, our overall findings indicate no differences in the expression levels of the cytokines IL-1β, IL-6, TNF-α, and iNOS in pregnant women with and without periodontal disease in comparison with expression of the same genes in non-pregnant women with and without periodontal disease, suggesting that periodontal disease is not influenced by pregnancy. MenosPeriodontal disease is one of the most prevalent oral diseases. An association between this disease and pregnancy has been suggested, but available findings are controversial. We evaluated the expression levels of interleukins (IL-1β and IL-6), tumor necrosis factor-alpha (TNF-α), and inducible nitric oxide synthase (iNOS) in pregnant women with and without periodontal disease in comparison with non-pregnant women with and without periodontal disease since studies have suggested a relationship between periodontitis and the expression levels of these genes. The women in the sample were distributed into four groups: pregnant and non-pregnant women, with or without periodontal disease, a total of 32 women. The periodontal condition was evaluated according to the probing depth, clinical attachment level and bleeding on probing. Analysis of gene expression was performed by real-time PCR. Comparisons were made of the level of gene expression among the four groups. Expression of IL-1β in the non-pregnant women with periodontal disease was 12.6 times higher than in the non-pregnant women without periodontal disease (P < 0.01), while expression of TNF-α in the non-pregnant women without periodontal disease was 3.5 times higher than in the pregnant women with periodontal disease (P < 0.05). Despite these differences, our overall findings indicate no differences in the expression levels of the cytokines IL-1β, IL-6, TNF-α, and iNOS in pregnant women with and without periodontal disease... Mostrar Tudo |
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Palavras-Chave: |
Gengiva; Periodonto. |
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Categoria do assunto: |
H Saúde e Patologia |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/948391/1/Expression-of-IL-1B-IL-6-TNF-a-and-iNOS-in-pregnant.pdf
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Marc: |
LEADER 02389naa a2200229 a 4500
001 1948391
005 2024-02-08
008 2012 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.4238/2012.september.20.3$2DOI
100 1 $aOTENIO, C. C. M.
245 $aExpression of IL-1B, IL-6, TNF-a and iNOS in pregnant women with periodontal disease.$h[electronic resource]
260 $c2012
520 $aPeriodontal disease is one of the most prevalent oral diseases. An association between this disease and pregnancy has been suggested, but available findings are controversial. We evaluated the expression levels of interleukins (IL-1β and IL-6), tumor necrosis factor-alpha (TNF-α), and inducible nitric oxide synthase (iNOS) in pregnant women with and without periodontal disease in comparison with non-pregnant women with and without periodontal disease since studies have suggested a relationship between periodontitis and the expression levels of these genes. The women in the sample were distributed into four groups: pregnant and non-pregnant women, with or without periodontal disease, a total of 32 women. The periodontal condition was evaluated according to the probing depth, clinical attachment level and bleeding on probing. Analysis of gene expression was performed by real-time PCR. Comparisons were made of the level of gene expression among the four groups. Expression of IL-1β in the non-pregnant women with periodontal disease was 12.6 times higher than in the non-pregnant women without periodontal disease (P < 0.01), while expression of TNF-α in the non-pregnant women without periodontal disease was 3.5 times higher than in the pregnant women with periodontal disease (P < 0.05). Despite these differences, our overall findings indicate no differences in the expression levels of the cytokines IL-1β, IL-6, TNF-α, and iNOS in pregnant women with and without periodontal disease in comparison with expression of the same genes in non-pregnant women with and without periodontal disease, suggesting that periodontal disease is not influenced by pregnancy.
653 $aGengiva
653 $aPeriodonto
700 1 $aFONSECA, I.
700 1 $aMARTINS, M. F.
700 1 $aRIBEIRO, L. C.
700 1 $aASSIS, N. M. S. P.
700 1 $aFERREIRA, A. P.
700 1 $aRIBEIRO, R. A.
773 $tGenetics and Molecular Research$gv. 11, n. 4, p. 4468-4478, 2012.
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Registro original: |
Embrapa Gado de Leite (CNPGL) |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Agricultura Digital. Para informações adicionais entre em contato com cnptia.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Agricultura Digital. |
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Data corrente: |
18/12/1995 |
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Data da última atualização: |
19/12/2007 |
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Autoria: |
FIGUEIREDO, A. M. C. M.; GUSMAO, G. L.; TSURUTA, J. H.; FREITAS, J. B. P. G. de; CAMARGO NETO, J.; LUZ, M. de C. P. da; ARGOLLO JUNIOR, M. de T. e; COLOMBO, R. M. T. |
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Afiliação: |
EMBRAPA-CNPTIA. |
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Título: |
Iconus: a user interface management system. |
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Ano de publicação: |
1990 |
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Fonte/Imprenta: |
In: INTERNATIONAL WORKSHOP ON THE BRAZILIAN SOFTWARE PLANT PROJECT, 2., 1990, Campinas. Proceedings... Campinas: Banco do Brasil: EMBRAPA-NTIA: CTI, 1990. |
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Páginas: |
p. 57-71. |
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Idioma: |
Inglês |
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Conteúdo: |
This paper describes Iconus, a user interface management system, through its structure, functionality, implementation details and its role in a software production integrated environment. Detailed steps to create a presentation object are described and directions for next increments are also reported. |
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Palavras-Chave: |
Ambiente integrado de producao de software; Ferramentas de software; Interface de usuario; Object-oriented system; Sistema orientado a objetos; Software production integrated environment; Software tools. |
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Thesaurus NAL: |
user interface. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 01346naa a2200313 a 4500
001 1002190
005 2007-12-19
008 1990 bl uuuu u00u1 u #d
100 1 $aFIGUEIREDO, A. M. C. M.
245 $aIconus$ba user interface management system.
260 $c1990
300 $ap. 57-71.
520 $aThis paper describes Iconus, a user interface management system, through its structure, functionality, implementation details and its role in a software production integrated environment. Detailed steps to create a presentation object are described and directions for next increments are also reported.
650 $auser interface
653 $aAmbiente integrado de producao de software
653 $aFerramentas de software
653 $aInterface de usuario
653 $aObject-oriented system
653 $aSistema orientado a objetos
653 $aSoftware production integrated environment
653 $aSoftware tools
700 1 $aGUSMAO, G. L.
700 1 $aTSURUTA, J. H.
700 1 $aFREITAS, J. B. P. G. de
700 1 $aCAMARGO NETO, J.
700 1 $aLUZ, M. de C. P. da
700 1 $aARGOLLO JUNIOR, M. de T. e
700 1 $aCOLOMBO, R. M. T.
773 $tIn: INTERNATIONAL WORKSHOP ON THE BRAZILIAN SOFTWARE PLANT PROJECT, 2., 1990, Campinas. Proceedings... Campinas: Banco do Brasil: EMBRAPA-NTIA: CTI, 1990.
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