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 | Acesso ao texto completo restrito à biblioteca da Embrapa Meio Ambiente. Para informações adicionais entre em contato com cnpma.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Amazônia Ocidental; Embrapa Meio Ambiente. |
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Data corrente: |
25/11/2021 |
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Data da última atualização: |
10/06/2022 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
CORDEIRO, R. P.; BRAGA, P. A. de C.; JONSSON, C. M.; BRANDÃO, F. R.; CHAGAS, E. C.; REYES, F. G. R. |
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Afiliação: |
RAFAELLE PEREIRA CORDEIRO, UNICAMP; PATRÍCIA APARECIDA DE CAMPOS BRAGA, UNICAMP; CLAUDIO MARTIN JONSSON, CNPMA; FRANMIR RODRIGUES BRANDÃO, Bolsista CPAA; EDSANDRA CAMPOS CHAGAS, CPAA; FELIX GUILLERMO REYES REYES, UNICAMP. |
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Título: |
Therapeutic efficacy and bioaccumulation of albendazole in the treatment of tambaqui (Colossoma macropomum) parasitized by acanthocephalan (Neoechinorhynchus buttnerae). |
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Ano de publicação: |
2022 |
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Fonte/Imprenta: |
Aquaculture Research, v. 53, n. 4, p. 1446-1455, 2022. |
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DOI: |
https://doi.org/10.1111/are.15677 |
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Idioma: |
Inglês |
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Conteúdo: |
The therapeutic efficacy of different doses of albendazole (ABZ) in the treatment of infection by acanthocephalan (Neoechinorhynchus buttnerae) in tambaqui (Colossoma macropomum) was evaluated. The bioaccumulation of ABZ and its main metabolites in the target tissue (muscle plus skin in natural proportions) was also evaluated. The fish received a daily dose of 10, 20 or 30 mg ABZ kg-1 bw via medicated feed for 34 days. Incorporation of ABZ in the fish feed was performed by coating with ethyl cellulose (EC) (0.75% w/w). The quantitation of ABZ residues and its metabolites in the target tissue was done using a validated ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) analytical method. In relation with the therapeutic efficacy, no statistically difference was found between the treated groups. The total residue (sum of ABZ residues and its metabolites) in the target tissue at steady-state was significantly higher for the high dose. Biomagnification factors in all treatments were of low values, indicating that ABZ and its metabolites do not offer the risk of bioaccumulation in the target tissue. Thus, ABZ dose of 10 mg kg-1 bw is recommend. However, the effect of feed coating on treatment effectiveness and bioaccumulation of albendazole relative to an uncoated feed, and joint therapeutic studies of ABZ with anthelmintic natural products are recommended to be conducted. |
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Palavras-Chave: |
Acanthocephalan; Neoechinorhynchus buttnerae; Therapeutic efficacy. |
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Thesagro: |
Colossoma Macropomum; Tambaqui; Verminose. |
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Thesaurus Nal: |
Albendazole; Bioaccumulation; Freshwater fish. |
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Categoria do assunto: |
--
H Saúde e Patologia |
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Marc: |
LEADER 02403naa a2200301 a 4500
001 2136674
005 2022-06-10
008 2022 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1111/are.15677$2DOI
100 1 $aCORDEIRO, R. P.
245 $aTherapeutic efficacy and bioaccumulation of albendazole in the treatment of tambaqui (Colossoma macropomum) parasitized by acanthocephalan (Neoechinorhynchus buttnerae).$h[electronic resource]
260 $c2022
520 $aThe therapeutic efficacy of different doses of albendazole (ABZ) in the treatment of infection by acanthocephalan (Neoechinorhynchus buttnerae) in tambaqui (Colossoma macropomum) was evaluated. The bioaccumulation of ABZ and its main metabolites in the target tissue (muscle plus skin in natural proportions) was also evaluated. The fish received a daily dose of 10, 20 or 30 mg ABZ kg-1 bw via medicated feed for 34 days. Incorporation of ABZ in the fish feed was performed by coating with ethyl cellulose (EC) (0.75% w/w). The quantitation of ABZ residues and its metabolites in the target tissue was done using a validated ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) analytical method. In relation with the therapeutic efficacy, no statistically difference was found between the treated groups. The total residue (sum of ABZ residues and its metabolites) in the target tissue at steady-state was significantly higher for the high dose. Biomagnification factors in all treatments were of low values, indicating that ABZ and its metabolites do not offer the risk of bioaccumulation in the target tissue. Thus, ABZ dose of 10 mg kg-1 bw is recommend. However, the effect of feed coating on treatment effectiveness and bioaccumulation of albendazole relative to an uncoated feed, and joint therapeutic studies of ABZ with anthelmintic natural products are recommended to be conducted.
650 $aAlbendazole
650 $aBioaccumulation
650 $aFreshwater fish
650 $aColossoma Macropomum
650 $aTambaqui
650 $aVerminose
653 $aAcanthocephalan
653 $aNeoechinorhynchus buttnerae
653 $aTherapeutic efficacy
700 1 $aBRAGA, P. A. de C.
700 1 $aJONSSON, C. M.
700 1 $aBRANDÃO, F. R.
700 1 $aCHAGAS, E. C.
700 1 $aREYES, F. G. R.
773 $tAquaculture Research$gv. 53, n. 4, p. 1446-1455, 2022.
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Registro original: |
Embrapa Meio Ambiente (CNPMA) |
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| Registros recuperados : 28 | |
| 21. |  | MARTINS, T.; SCHINKE, C.; QUEIROZ, S. C. do N. de; BRAGA, P A. de C.; SILVA, F. S. P.; MELO, I. S. de; REYES, F. G. R. Role of bioactive metabolites from Acremonium camptosporum associated with the marine sponge Aplysina fulva. Chemosphere, v. 274, article 129753, 2021.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Meio Ambiente. |
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| 23. | | HASHIMOTO, J. C.; PASCHOAL, J. A. R.; QUEIROZ, S. C. do N. de; FERRACINI, V. L.; ASSALIN, M. R.; REYES, F. G. R. A simple method for the determination of malachite green and leucomalachite green residues in fish by a modified QuEChERS extraction and LC/MS/MS. Journal of AOAC International, Arlington, v. 95, n. 3, p. 913-922, 2012.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Meio Ambiente. |
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| 24. | | CORDEIRO, R. P.; BRAGA, P. A. de C.; JONSSON, C. M.; BRANDÃO, F. R.; CHAGAS, E. C.; REYES, F. G. R. Therapeutic efficacy and bioaccumulation of albendazole in the treatment of tambaqui (Colossoma macropomum) parasitized by acanthocephalan (Neoechinorhynchus buttnerae). Aquaculture Research, v. 53, n. 4, p. 1446-1455, 2022.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Amazônia Ocidental; Embrapa Meio Ambiente. |
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| 25. | | SAMPAIO, F. G.; CARRA, M. L.; JONSSON, C. M.; GONÇALVES, V. T.; DAL'BÓ, G. A.; NUNES, K. S. D.; VALLIM, J. H.; DALLAGO, B. S. L.; QUEIROZ, S. C. do N. de; REYES, F. G. R. Effects of dietary exposure to sulfamethazine on the hematological parameters and hepatic oxidative stress biomarkers in nile tilapia (Oreochromis niloticus). Bulletin of Environmental Contamination and Toxicology, California, v. 97, n. 4, p. 528-535, 2016.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Meio Ambiente. |
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| 26. | | CARRA, M. L.; THOMAZ, J. M.; SAMPAIO, F. G.; DAMACENA, K.; REYES, F. G. R.; VALLIM, J. H.; JONSSON, C. M.; DAL'BÓ, G. A.; SANTANA, F.; GONÇALVES, V. T. Efeito da administração de sulfonamidas na hematologia de tilápia do nilo (Oreochromis niloticus). In: CONGRESSO NACIONAL DE INICIAÇÃO CIENTÍFICA, 13., 2013, Campinas. Anais... Campinas: Sindicato das Entidades Mantenedoras de Ensino Superior (Semesp), 2013. 10 p.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Meio Ambiente. |
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| 27. | | BAPTISTA, R. C.; FERNANDES, M. A. M.; GILAVERTE, S.; QUEIROZ, S. C. do N. de; ASSALIN, M. R.; FERRACINI, V. L.; MONTEIRO, A. L. G.; REYES, F. G. R. Determination of moxidectin in serum by liquid chromatography-tandem mass spectrometry and its application in pharmacokinetic study in lambs. Journal of the Brazilian Chemical Society, Campinas, v. 28, n. 2, p. 250-256, 2017.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Meio Ambiente. |
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| 28. | | BAPTISTA, R. C.; FERNANDES, M. A. M.; GILAVERTE, S.; QUEIROZ, S. C. do N. de; FERRACINI, V. L.; ASSALIN, M. R.; MONTEIRO, A. L. G.; REYES, F. G. R. Pharmacokinetic parameters of moxidectin residue in the serum of lambs. In: ANNUAL MEETING BRAZILIAN SOCIETY OF ANIMAL SCIENCE, 50., 2013, Campinas. The integration of knowledge in animal production: abstracts. Campinas: SBZ, 2013. 1 CD ROM.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Meio Ambiente. |
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| Registros recuperados : 28 | |
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| Nenhum registro encontrado para a expressão de busca informada. |
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