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 | Acesso ao texto completo restrito à biblioteca da Embrapa Meio Ambiente. Para informações adicionais entre em contato com cnpma.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Meio Ambiente. |
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Data corrente: |
01/11/2018 |
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Data da última atualização: |
01/11/2018 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
BARRETO, F. M.; SILVA, M. R. da; BRAGA, P. A. C.; BRAGOTTO, A. P. A.; HISANO, H.; REYES, F. G. R. |
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Afiliação: |
FABIOLA MALAGA BARRETO, FEA-UNICAMP; MARIANA R DA SILVA, FEA-UNICAMP; PATRICIA APARECIDA DE CAMPOS BRAGA, FEA-UNICAMP; ADRIANA PAVESI ARISSETO BRAGOTTO, FEA-UNICAMP; HAMILTON HISANO, CNPMA; FELIX GUILLERMO REYES REYES, FEA-UNICAMP. |
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Título: |
Evaluation of the leaching of florfenicol from coated medicated fish feed into water. |
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Ano de publicação: |
2018 |
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Fonte/Imprenta: |
Environmental Pollution, v. 242, Part B, p. 1245-1252, 2018. |
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ISSN: |
0269-7491 |
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DOI: |
https://doi.org/10.1016/j.envpol.2018.08.017 |
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Idioma: |
Inglês |
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Conteúdo: |
Florfenicol is one of the most-used antimicrobial agents in global fish farming. Nevertheless, in most countries, its use is not conducted in accordance with good practices. The aim of this work was to evaluate the leaching of florfenicol from coated fish feed into the water. Analytical methods were developed and validated for the quantitation of florfenicol in medicated feed and water by UHPLC-MS/MS. Florfenicol residues in the water were quantified after 5- and 15-min exposures of the medicated feed in the water at 22 and 28°C and at pH 4.5 and 8.0. The influence of pellet size and three coating agents (vegetable oil, carboxymethylcellulose, and low-methoxylated pectin) on the leaching of the drug was also assessed. Pellet size, coating agent, water temperature, and time of exposure significantly (p <0.05) affected florfenicol leaching, while water pH did not interfere with the leaching. Coating with vegetable oil was the most efficient method to reduce florfenicol leaching, while coating with carboxymethylcellulose presented the highest leaching (approximately 60% after 15 min at 28°C). Thus, the coating agent has a significant effect on the florfenicol leaching rate and, consequently, on the necessary dose of the drug to be administered. Moreover, it is worth mentioning that higher florfenicol leaching will pose a greater risk to environmental health, specifically in terms of the development of bacteria resistant to florfenicol. Additional studies are needed with other polymers and veterinary drugs used in medicated feed for fish farming. MenosFlorfenicol is one of the most-used antimicrobial agents in global fish farming. Nevertheless, in most countries, its use is not conducted in accordance with good practices. The aim of this work was to evaluate the leaching of florfenicol from coated fish feed into the water. Analytical methods were developed and validated for the quantitation of florfenicol in medicated feed and water by UHPLC-MS/MS. Florfenicol residues in the water were quantified after 5- and 15-min exposures of the medicated feed in the water at 22 and 28°C and at pH 4.5 and 8.0. The influence of pellet size and three coating agents (vegetable oil, carboxymethylcellulose, and low-methoxylated pectin) on the leaching of the drug was also assessed. Pellet size, coating agent, water temperature, and time of exposure significantly (p <0.05) affected florfenicol leaching, while water pH did not interfere with the leaching. Coating with vegetable oil was the most efficient method to reduce florfenicol leaching, while coating with carboxymethylcellulose presented the highest leaching (approximately 60% after 15 min at 28°C). Thus, the coating agent has a significant effect on the florfenicol leaching rate and, consequently, on the necessary dose of the drug to be administered. Moreover, it is worth mentioning that higher florfenicol leaching will pose a greater risk to environmental health, specifically in terms of the development of bacteria resistant to florfenicol. Additional studies are needed with other p... Mostrar Tudo |
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Thesagro: |
Antibiótico; Florfenicol; Lixiviação; Piscicultura. |
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Thesaurus Nal: |
Antibiotics; Carboxymethylcellulose; Fish feeds; Leaching; Pectins. |
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Categoria do assunto: |
P Recursos Naturais, Ciências Ambientais e da Terra |
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Marc: |
LEADER 02473naa a2200313 a 4500
001 2098693
005 2018-11-01
008 2018 bl uuuu u00u1 u #d
022 $a0269-7491
024 7 $ahttps://doi.org/10.1016/j.envpol.2018.08.017$2DOI
100 1 $aBARRETO, F. M.
245 $aEvaluation of the leaching of florfenicol from coated medicated fish feed into water.$h[electronic resource]
260 $c2018
520 $aFlorfenicol is one of the most-used antimicrobial agents in global fish farming. Nevertheless, in most countries, its use is not conducted in accordance with good practices. The aim of this work was to evaluate the leaching of florfenicol from coated fish feed into the water. Analytical methods were developed and validated for the quantitation of florfenicol in medicated feed and water by UHPLC-MS/MS. Florfenicol residues in the water were quantified after 5- and 15-min exposures of the medicated feed in the water at 22 and 28°C and at pH 4.5 and 8.0. The influence of pellet size and three coating agents (vegetable oil, carboxymethylcellulose, and low-methoxylated pectin) on the leaching of the drug was also assessed. Pellet size, coating agent, water temperature, and time of exposure significantly (p <0.05) affected florfenicol leaching, while water pH did not interfere with the leaching. Coating with vegetable oil was the most efficient method to reduce florfenicol leaching, while coating with carboxymethylcellulose presented the highest leaching (approximately 60% after 15 min at 28°C). Thus, the coating agent has a significant effect on the florfenicol leaching rate and, consequently, on the necessary dose of the drug to be administered. Moreover, it is worth mentioning that higher florfenicol leaching will pose a greater risk to environmental health, specifically in terms of the development of bacteria resistant to florfenicol. Additional studies are needed with other polymers and veterinary drugs used in medicated feed for fish farming.
650 $aAntibiotics
650 $aCarboxymethylcellulose
650 $aFish feeds
650 $aLeaching
650 $aPectins
650 $aAntibiótico
650 $aFlorfenicol
650 $aLixiviação
650 $aPiscicultura
700 1 $aSILVA, M. R. da
700 1 $aBRAGA, P. A. C.
700 1 $aBRAGOTTO, A. P. A.
700 1 $aHISANO, H.
700 1 $aREYES, F. G. R.
773 $tEnvironmental Pollution$gv. 242, Part B, p. 1245-1252, 2018.
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Registro original: |
Embrapa Meio Ambiente (CNPMA) |
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| Registros recuperados : 28 | |
| 21. |  | MARTINS, T.; SCHINKE, C.; QUEIROZ, S. C. do N. de; BRAGA, P A. de C.; SILVA, F. S. P.; MELO, I. S. de; REYES, F. G. R. Role of bioactive metabolites from Acremonium camptosporum associated with the marine sponge Aplysina fulva. Chemosphere, v. 274, article 129753, 2021.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Meio Ambiente. |
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| 23. | | HASHIMOTO, J. C.; PASCHOAL, J. A. R.; QUEIROZ, S. C. do N. de; FERRACINI, V. L.; ASSALIN, M. R.; REYES, F. G. R. A simple method for the determination of malachite green and leucomalachite green residues in fish by a modified QuEChERS extraction and LC/MS/MS. Journal of AOAC International, Arlington, v. 95, n. 3, p. 913-922, 2012.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Meio Ambiente. |
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| 24. | | CORDEIRO, R. P.; BRAGA, P. A. de C.; JONSSON, C. M.; BRANDÃO, F. R.; CHAGAS, E. C.; REYES, F. G. R. Therapeutic efficacy and bioaccumulation of albendazole in the treatment of tambaqui (Colossoma macropomum) parasitized by acanthocephalan (Neoechinorhynchus buttnerae). Aquaculture Research, v. 53, n. 4, p. 1446-1455, 2022.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Amazônia Ocidental; Embrapa Meio Ambiente. |
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| 25. | | SAMPAIO, F. G.; CARRA, M. L.; JONSSON, C. M.; GONÇALVES, V. T.; DAL'BÓ, G. A.; NUNES, K. S. D.; VALLIM, J. H.; DALLAGO, B. S. L.; QUEIROZ, S. C. do N. de; REYES, F. G. R. Effects of dietary exposure to sulfamethazine on the hematological parameters and hepatic oxidative stress biomarkers in nile tilapia (Oreochromis niloticus). Bulletin of Environmental Contamination and Toxicology, California, v. 97, n. 4, p. 528-535, 2016.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Meio Ambiente. |
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| 26. | | CARRA, M. L.; THOMAZ, J. M.; SAMPAIO, F. G.; DAMACENA, K.; REYES, F. G. R.; VALLIM, J. H.; JONSSON, C. M.; DAL'BÓ, G. A.; SANTANA, F.; GONÇALVES, V. T. Efeito da administração de sulfonamidas na hematologia de tilápia do nilo (Oreochromis niloticus). In: CONGRESSO NACIONAL DE INICIAÇÃO CIENTÍFICA, 13., 2013, Campinas. Anais... Campinas: Sindicato das Entidades Mantenedoras de Ensino Superior (Semesp), 2013. 10 p.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Meio Ambiente. |
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| 27. | | BAPTISTA, R. C.; FERNANDES, M. A. M.; GILAVERTE, S.; QUEIROZ, S. C. do N. de; ASSALIN, M. R.; FERRACINI, V. L.; MONTEIRO, A. L. G.; REYES, F. G. R. Determination of moxidectin in serum by liquid chromatography-tandem mass spectrometry and its application in pharmacokinetic study in lambs. Journal of the Brazilian Chemical Society, Campinas, v. 28, n. 2, p. 250-256, 2017.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Meio Ambiente. |
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| 28. | | BAPTISTA, R. C.; FERNANDES, M. A. M.; GILAVERTE, S.; QUEIROZ, S. C. do N. de; FERRACINI, V. L.; ASSALIN, M. R.; MONTEIRO, A. L. G.; REYES, F. G. R. Pharmacokinetic parameters of moxidectin residue in the serum of lambs. In: ANNUAL MEETING BRAZILIAN SOCIETY OF ANIMAL SCIENCE, 50., 2013, Campinas. The integration of knowledge in animal production: abstracts. Campinas: SBZ, 2013. 1 CD ROM.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Meio Ambiente. |
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| Registros recuperados : 28 | |
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| Nenhum registro encontrado para a expressão de busca informada. |
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