Data/hora: 22/09/2024 23:59:45

Biblioteca(s): 	Embrapa Florestas; Embrapa Recursos Genéticos e Biotecnologia.	
Data corrente: 	09/02/2011	
Data da última atualização: 	16/09/2015	
Autoria: 	GRATTAPAGLIA, D.; RESENDE, M. D. V. de.	
Afiliação: 	DARIO GRATTAPAGLIA, CENARGEN; MARCOS DEON VILELA DE RESENDE, CNPF.	
Título: 	Genomic selection in forest tree breeding.	
Ano de publicação: 	2011	
Fonte/Imprenta: 	Tree Genetics & Genomes, v. 7, n. 2, p. 241-255, Apr. 2011.	
DOI: 	10.1007/s11295-010-0328-4	
Idioma: 	Inglês	
Conteúdo: 	Genomic selection (GS) involves selection decisions based on genomic breeding values estimated as the sum of the effects of genome-wide markers capturing most quantitative trait loci (QTL) for the target trait(s). GS is revolutionizing breeding practice in domestic animals. The same approach and concepts can be readily applied to forest tree breeding where long generation times and late expressing complex traits are also a challenge. GS in forest trees would have additional advantages: large training populations can be easily assembled and accurately phenotyped for several traits, and the extent of linkage disequilibrium (LD) can be high in elite populations with small effective population size (Ne) frequently used in advanced forest tree breeding programs. Deterministic equations were used to assess the impact of LD (modeled by Ne and intermarker distance), the size of the training set, trait heritability, and the number of QTL on the predicted accuracy of GS. Results indicate that GS has the potential to radically improve the efficiency of tree breeding. The benchmark accuracy of conventional BLUP selection is reached by GS even at a marker density ~2 markers/cM when Ne?30, while up to 20 markers/cM are necessary for larger Ne. Shortening the breeding cycle by 50% with GS provides an increase ?100% in selection efficiency. With the rapid technological advances and declining costs of genotyping, our cautiously optimistic outlook is that GS has great potential to accelerate tree breeding. However, further simulation studies and proof-of-concept experiments of GS are needed before recommending it for operational implementation.	
Palavras-Chave: 	Genome-wide selection; Melhoramento florestal; Seleção genômica.	
Thesaurus Nal: 	linkage disequilibrium; marker-assisted selection.	
Categoria do assunto: 	--	
Registro original: 	Embrapa Florestas (CNPF)	
Exemplares: 	CNPF - (47884-1) - UPC - AP - DD -  -  -  - DIS
CENARGEN - (33023-1) - UPA - AP - DD -  -  -  - DIS