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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
30/08/2016 |
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Data da última atualização: |
03/10/2016 |
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Autoria: |
REIS, P. J.; TUNKS, D. A.; DOWNES, A. M. |
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Título: |
Mimosine, administered orally, and two related compounds of chemical defleecing agents for sheep. |
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Ano de publicação: |
1978 |
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Fonte/Imprenta: |
Australian Journal of Agricultural Research, v. 29, n. 5, p. 1065-1075, 1978. |
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DOI: |
10.1071/AR9781065 |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: Oral doses of mimosine (ranging from 400 to 800 mg/kg body weight) were given to 71 sheep, either as two successive daily doses (10 sheep) or as a single dose (61 sheep). The effectiveness of these treatments for defleecing was assessed and in some sheep measurements were made of the concentration of mimosine in plasma after dosing, and of the rate of wool growth before and after dosing. In addition, the effectiveness as defleecing agents of two related compounds (an analogue of mimosine, 'isomimosine', and a metabolite, 3,4-dihydroxypyridine (DHP)) was assessed. Two successive daily doses of mimosine (300 mg/kg/day) allowed all sheep to be defleeced. With sheep consuming a daily ration of 600 g, a single oral dose of mimosine (400 mg/kg) was sufficient to allow defleecing of most sheep; when the daily ration was 1200 g, a dose of 600 mg/kg was required to allow defleecing of most sheep. The effectiveness of oral doses for defleecing could be explained by the absorption of mimosine over a period in excess of 24 hr. Concentrations of mimosine in plasma were usually above 100 µmoles/l 24 hr after an effective dose. Failure to achieve complete cessation of fibre growth occurred occasionally, irrespective of dose level, and two sheep died after dosing. Fasting prior to dosing appeared to obviate the effects of previous high nutrition, but increased the risk of toxic effects. Fasting resulted in exceptionally high concentrations of mimosine in plasma (200?300 µmoles/l) 1 and 2 days after dosing. Both fibre diameter and mass of wool grown were increased in the early regrowth after dosing with mimosine. 'Isomimosine' had a similar potency to mimosine for stopping fibre growth in sheep, whether given as an intravenous infusion or as a single oral dose. DHP, given as an intravenous infusion, was ineffective as a defleecing agent. MenosAbstract: Oral doses of mimosine (ranging from 400 to 800 mg/kg body weight) were given to 71 sheep, either as two successive daily doses (10 sheep) or as a single dose (61 sheep). The effectiveness of these treatments for defleecing was assessed and in some sheep measurements were made of the concentration of mimosine in plasma after dosing, and of the rate of wool growth before and after dosing. In addition, the effectiveness as defleecing agents of two related compounds (an analogue of mimosine, 'isomimosine', and a metabolite, 3,4-dihydroxypyridine (DHP)) was assessed. Two successive daily doses of mimosine (300 mg/kg/day) allowed all sheep to be defleeced. With sheep consuming a daily ration of 600 g, a single oral dose of mimosine (400 mg/kg) was sufficient to allow defleecing of most sheep; when the daily ration was 1200 g, a dose of 600 mg/kg was required to allow defleecing of most sheep. The effectiveness of oral doses for defleecing could be explained by the absorption of mimosine over a period in excess of 24 hr. Concentrations of mimosine in plasma were usually above 100 µmoles/l 24 hr after an effective dose. Failure to achieve complete cessation of fibre growth occurred occasionally, irrespective of dose level, and two sheep died after dosing. Fasting prior to dosing appeared to obviate the effects of previous high nutrition, but increased the risk of toxic effects. Fasting resulted in exceptionally high concentrations of mimosine in plasma (200?300 µmoles/l) ... Mostrar Tudo |
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Palavras-Chave: |
Mimosina. |
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Thesagro: |
Nutrição animal; Ovino. |
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Thesaurus Nal: |
Animal nutrition; Mimosine; Sheep. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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Marc: |
LEADER 02519naa a2200229 a 4500
001 2052097
005 2016-10-03
008 1978 bl uuuu u00u1 u #d
024 7 $a10.1071/AR9781065$2DOI
100 1 $aREIS, P. J.
245 $aMimosine, administered orally, and two related compounds of chemical defleecing agents for sheep.
260 $c1978
520 $aAbstract: Oral doses of mimosine (ranging from 400 to 800 mg/kg body weight) were given to 71 sheep, either as two successive daily doses (10 sheep) or as a single dose (61 sheep). The effectiveness of these treatments for defleecing was assessed and in some sheep measurements were made of the concentration of mimosine in plasma after dosing, and of the rate of wool growth before and after dosing. In addition, the effectiveness as defleecing agents of two related compounds (an analogue of mimosine, 'isomimosine', and a metabolite, 3,4-dihydroxypyridine (DHP)) was assessed. Two successive daily doses of mimosine (300 mg/kg/day) allowed all sheep to be defleeced. With sheep consuming a daily ration of 600 g, a single oral dose of mimosine (400 mg/kg) was sufficient to allow defleecing of most sheep; when the daily ration was 1200 g, a dose of 600 mg/kg was required to allow defleecing of most sheep. The effectiveness of oral doses for defleecing could be explained by the absorption of mimosine over a period in excess of 24 hr. Concentrations of mimosine in plasma were usually above 100 µmoles/l 24 hr after an effective dose. Failure to achieve complete cessation of fibre growth occurred occasionally, irrespective of dose level, and two sheep died after dosing. Fasting prior to dosing appeared to obviate the effects of previous high nutrition, but increased the risk of toxic effects. Fasting resulted in exceptionally high concentrations of mimosine in plasma (200?300 µmoles/l) 1 and 2 days after dosing. Both fibre diameter and mass of wool grown were increased in the early regrowth after dosing with mimosine. 'Isomimosine' had a similar potency to mimosine for stopping fibre growth in sheep, whether given as an intravenous infusion or as a single oral dose. DHP, given as an intravenous infusion, was ineffective as a defleecing agent.
650 $aAnimal nutrition
650 $aMimosine
650 $aSheep
650 $aNutrição animal
650 $aOvino
653 $aMimosina
700 1 $aTUNKS, D. A.
700 1 $aDOWNES, A. M.
773 $tAustralian Journal of Agricultural Research$gv. 29, n. 5, p. 1065-1075, 1978.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Agrossilvipastoril. Para informações adicionais entre em contato com cpamt.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Agrossilvipastoril; Embrapa Soja. |
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Data corrente: |
09/05/2018 |
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Data da última atualização: |
09/05/2018 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
LANA, F. D.; PAUL, P. A.; GODOY, C. V.; UTIAMADA, C. M.; SILVA, L. H. C. P. da; SIQUERI, F. V.; FORCELINI, C. A.; JACCOUD-FILHO, D. de S.; WRUCK, D. S. M.; BORGES, E. P.; JULIATTI, F. C.; CAMPOS, H. D.; NUNES JUNIOR, J.; CARNEIRO, L. C.; CANTERI, M. G.; ITO, M. F.; MEYER, M. C.; MARTINS, M. C.; BALARDIN, R. S.; FURLAN, S. H.; CARLIN, V. J.; DEL PONTE, E. M. |
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Afiliação: |
OSU; OSU; CLAUDIA VIEIRA GODOY, CNPSO; TAGRO, LONDRINA; AGRO CARREGAL, RIO VERDE, GO; FUNDAÇÃO MT, RONDONÓPOLIS, MT; UPF; UEPG; DULANDULA SILVA MIGUEL WRUCK, CPAMT; FUNDAÇÃO CHAPADÃO, CHAPADÃO DO SUL, MS; UFU; UNIRV; CTPA, GOIÂNIA, GO; UFG, JATAÍ, GO; UEL; IAC; MAURICIO CONRADO MEYER, CNPSO; CÍRCULO VERDE, LUÍS EDUARDO MAGALHÃES, BA; UFSM; IB, CAMPINAS; AGRODINÂMICA, TANGARÁ DA sERRA, MT; UFV. |
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Título: |
Meta-analytic modeling of the decline in performance of fungicides for managing soybean rust after a decade of use in Brazil. |
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Ano de publicação: |
2018 |
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Fonte/Imprenta: |
Plant disease, v. 102, n. 4, p. 807-817, Apr. 2018. |
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DOI: |
10.1094/PDIS-03-17-0408-RE |
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Idioma: |
Inglês |
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Conteúdo: |
An apparent decline of fungicide performance for the control of soybean rust in Brazil has been reported but the rate at which it has occurred has not been formally quantified. Control efficacy and yield response to three fungicides applied as single active ingredients (a.i.)?azoxystrobin (AZOX), cyproconazole (CYPR), and tebuconazole (TEBU)?and four applied as mixtures?AZOX+CYPR, picoxystrobin + CYPR, pyraclostrobin + epoxiconazole, and trifloxystrobin + prothioconazole (TRIF+PROT)?were summarized using network meta-analytic models fitted to mean severity and yield data from 250 trials (10-year period). The effect of year was tested on both variables in a meta-regression model. Overall control efficacy ranged from 56 to 84%; the three single-a.i. fungicides performed the poorest (56 to 62%). Yield increase for single-a.i. fungicides was as low as 30% but ranged from 47 to 65% for the premixes. Significant declines in both variables were detected for all fungicides except TRIF+PROT. For TEBU, control efficacy (yield response) declined the most: 78% (18%) to 54% (8%) from 2004?05 to 2013?14. The recent surge of resistant populations of Phakopsora pachyrhizi to both demethylation inhibitor and quinone outside inhibitor fungicides is likely the driving force behind a significant decline after 4 years of fungicide use. |
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Palavras-Chave: |
Alternaria-solani; Azole resistance; Cytochrome-b gene; Field-resistance; Mycosphaerella-graminicola; Phakopsora-pachyrhizi; Q(O)i fungicides; QO inhibitor fungicides; Triazole-based fungicides. |
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Thesagro: |
Doença de Planta; Ferrugem; Fungicida; Fungo; Performance; Phakopsora Pachyrhizi; Soja. |
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Thesaurus NAL: |
Fungicides; Fusarium head blight; Microbial growth; Soybean rust; Soybeans. |
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Categoria do assunto: |
F Plantas e Produtos de Origem Vegetal
X Pesquisa, Tecnologia e Engenharia |
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Marc: |
LEADER 03143naa a2200637 a 4500
001 2091273
005 2018-05-09
008 2018 bl uuuu u00u1 u #d
024 7 $a10.1094/PDIS-03-17-0408-RE$2DOI
100 1 $aLANA, F. D.
245 $aMeta-analytic modeling of the decline in performance of fungicides for managing soybean rust after a decade of use in Brazil.$h[electronic resource]
260 $c2018
520 $aAn apparent decline of fungicide performance for the control of soybean rust in Brazil has been reported but the rate at which it has occurred has not been formally quantified. Control efficacy and yield response to three fungicides applied as single active ingredients (a.i.)?azoxystrobin (AZOX), cyproconazole (CYPR), and tebuconazole (TEBU)?and four applied as mixtures?AZOX+CYPR, picoxystrobin + CYPR, pyraclostrobin + epoxiconazole, and trifloxystrobin + prothioconazole (TRIF+PROT)?were summarized using network meta-analytic models fitted to mean severity and yield data from 250 trials (10-year period). The effect of year was tested on both variables in a meta-regression model. Overall control efficacy ranged from 56 to 84%; the three single-a.i. fungicides performed the poorest (56 to 62%). Yield increase for single-a.i. fungicides was as low as 30% but ranged from 47 to 65% for the premixes. Significant declines in both variables were detected for all fungicides except TRIF+PROT. For TEBU, control efficacy (yield response) declined the most: 78% (18%) to 54% (8%) from 2004?05 to 2013?14. The recent surge of resistant populations of Phakopsora pachyrhizi to both demethylation inhibitor and quinone outside inhibitor fungicides is likely the driving force behind a significant decline after 4 years of fungicide use.
650 $aFungicides
650 $aFusarium head blight
650 $aMicrobial growth
650 $aSoybean rust
650 $aSoybeans
650 $aDoença de Planta
650 $aFerrugem
650 $aFungicida
650 $aFungo
650 $aPerformance
650 $aPhakopsora Pachyrhizi
650 $aSoja
653 $aAlternaria-solani
653 $aAzole resistance
653 $aCytochrome-b gene
653 $aField-resistance
653 $aMycosphaerella-graminicola
653 $aPhakopsora-pachyrhizi
653 $aQ(O)i fungicides
653 $aQO inhibitor fungicides
653 $aTriazole-based fungicides
700 1 $aPAUL, P. A.
700 1 $aGODOY, C. V.
700 1 $aUTIAMADA, C. M.
700 1 $aSILVA, L. H. C. P. da
700 1 $aSIQUERI, F. V.
700 1 $aFORCELINI, C. A.
700 1 $aJACCOUD-FILHO, D. de S.
700 1 $aWRUCK, D. S. M.
700 1 $aBORGES, E. P.
700 1 $aJULIATTI, F. C.
700 1 $aCAMPOS, H. D.
700 1 $aNUNES JUNIOR, J.
700 1 $aCARNEIRO, L. C.
700 1 $aCANTERI, M. G.
700 1 $aITO, M. F.
700 1 $aMEYER, M. C.
700 1 $aMARTINS, M. C.
700 1 $aBALARDIN, R. S.
700 1 $aFURLAN, S. H.
700 1 $aCARLIN, V. J.
700 1 $aDEL PONTE, E. M.
773 $tPlant disease$gv. 102, n. 4, p. 807-817, Apr. 2018.
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Embrapa Soja (CNPSO) |
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