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Registro Completo |
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Biblioteca(s): |
Embrapa Cerrados. |
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Data corrente: |
29/11/2018 |
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Data da última atualização: |
29/11/2018 |
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Tipo da produção científica: |
Resumo em Anais de Congresso |
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Autoria: |
SILVA JUNIOR, O. B. da; PESSOA FILHO, M. A. C. de P.; SA, M. E. L.; DEAL, R.; RAGOUSSIS, I.; GRATTAPAGLIA, D.; RECH FILHO, E. L. |
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Afiliação: |
ORZENIL BONFIM DA SILVA JUNIOR, Cenargen; MARCO AURELIO CALDAS DE PINHO PESSO, CPAC; Cenargen; EMORY UNIVERSITY; MCGILL UNIVERSITY; DARIO GRATTAPAGLIA, Cenargen; ELIBIO LEOPOLDO RECH FILHO, Cenargen. |
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Título: |
Coupling in-depth genome annotations with genome editing technology for harnessing genomic variation to promote precision breeding in tropical soybean. |
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Ano de publicação: |
2018 |
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Fonte/Imprenta: |
In: BRAZILIAN BIOTECHNOLOGY CONGRESS, 7.; BIOTECHNOLOGY IBERO-AMERICAN CONGRESS, 2., 2018, Brasília, DF. Proceedings... Brasília, DF: SBBiotec, 2018. |
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Idioma: |
Inglês |
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Conteúdo: |
ABSTRACT: Directional selection during crop domestication and advanced breeding has resulted in significant changes in plant genomes. The extent of intraspecific variation in a crop documents domestication and highlights variants underlying complex traits. Studies demonstrate that most naturally occurring variants in crops are low frequency, and only a small fraction of those might have important functions to trait variation. To understand the inheritance of quantitative traits, diversity panels have become available by crossing inbred lines to produce genomic maps that relate phenotypic variation to recombination and ultimately to genome structure. Using these resources, genomics studies have suggested that selection performs poorly in pericentromeric regions because of reduced recombination frequency (RF). Thus, manipulating RF and meiotic crossover location is an appealing issue to advance crop breeding. In our study, we are using genomic analysis to characterize intragenomic diversity of tropical elite soybean lines in terms of heterozygosity, RF, chromatin structure and accessibility. Our results to date include the generation of draft genome assemblies for two soybean advanced lines using PACBIO long-read sequencing, Chromium Linked-Reads sequencing and an approach rooted in polymer physics that determines the most likely genome structure using chromosomal contact data. In-depth genome-wide characterization is ongoing using ATAC-Seq and Parent-Progeny resequencing. We also present our efforts to apply DNA-free editing tools in implementing genetic alterations that are expected to engineer desirable traits in soybeans by modifying meiotic specific expression. These changes are expected to increase genetic and epigenetic variations with favorable outcomes in seed oil and protein pathway regulation. Financial support: Embrapa-Monsanto Fund/Project:03.17.03.002.00.00 MenosABSTRACT: Directional selection during crop domestication and advanced breeding has resulted in significant changes in plant genomes. The extent of intraspecific variation in a crop documents domestication and highlights variants underlying complex traits. Studies demonstrate that most naturally occurring variants in crops are low frequency, and only a small fraction of those might have important functions to trait variation. To understand the inheritance of quantitative traits, diversity panels have become available by crossing inbred lines to produce genomic maps that relate phenotypic variation to recombination and ultimately to genome structure. Using these resources, genomics studies have suggested that selection performs poorly in pericentromeric regions because of reduced recombination frequency (RF). Thus, manipulating RF and meiotic crossover location is an appealing issue to advance crop breeding. In our study, we are using genomic analysis to characterize intragenomic diversity of tropical elite soybean lines in terms of heterozygosity, RF, chromatin structure and accessibility. Our results to date include the generation of draft genome assemblies for two soybean advanced lines using PACBIO long-read sequencing, Chromium Linked-Reads sequencing and an approach rooted in polymer physics that determines the most likely genome structure using chromosomal contact data. In-depth genome-wide characterization is ongoing using ATAC-Seq and Parent-Progeny resequencing. We ... Mostrar Tudo |
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Palavras-Chave: |
Análise genômica; Seqüenciamento de longa duração. |
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Thesagro: |
Genoma; Melhoramento Genético Vegetal; Soja. |
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Categoria do assunto: |
G Melhoramento Genético |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/187384/1/Coupling-in-depth-genome-annotations-with-genome-editing-technology-for-harnessing-genomic-variation-to-promote-precision-breeding-in-tropical-soybean-APAGAR.pdf
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Marc: |
LEADER 02810nam a2200241 a 4500
001 2100401
005 2018-11-29
008 2018 bl uuuu u00u1 u #d
100 1 $aSILVA JUNIOR, O. B. da
245 $aCoupling in-depth genome annotations with genome editing technology for harnessing genomic variation to promote precision breeding in tropical soybean.$h[electronic resource]
260 $aIn: BRAZILIAN BIOTECHNOLOGY CONGRESS, 7.; BIOTECHNOLOGY IBERO-AMERICAN CONGRESS, 2., 2018, Brasília, DF. Proceedings... Brasília, DF: SBBiotec$c2018
520 $aABSTRACT: Directional selection during crop domestication and advanced breeding has resulted in significant changes in plant genomes. The extent of intraspecific variation in a crop documents domestication and highlights variants underlying complex traits. Studies demonstrate that most naturally occurring variants in crops are low frequency, and only a small fraction of those might have important functions to trait variation. To understand the inheritance of quantitative traits, diversity panels have become available by crossing inbred lines to produce genomic maps that relate phenotypic variation to recombination and ultimately to genome structure. Using these resources, genomics studies have suggested that selection performs poorly in pericentromeric regions because of reduced recombination frequency (RF). Thus, manipulating RF and meiotic crossover location is an appealing issue to advance crop breeding. In our study, we are using genomic analysis to characterize intragenomic diversity of tropical elite soybean lines in terms of heterozygosity, RF, chromatin structure and accessibility. Our results to date include the generation of draft genome assemblies for two soybean advanced lines using PACBIO long-read sequencing, Chromium Linked-Reads sequencing and an approach rooted in polymer physics that determines the most likely genome structure using chromosomal contact data. In-depth genome-wide characterization is ongoing using ATAC-Seq and Parent-Progeny resequencing. We also present our efforts to apply DNA-free editing tools in implementing genetic alterations that are expected to engineer desirable traits in soybeans by modifying meiotic specific expression. These changes are expected to increase genetic and epigenetic variations with favorable outcomes in seed oil and protein pathway regulation. Financial support: Embrapa-Monsanto Fund/Project:03.17.03.002.00.00
650 $aGenoma
650 $aMelhoramento Genético Vegetal
650 $aSoja
653 $aAnálise genômica
653 $aSeqüenciamento de longa duração
700 1 $aPESSOA FILHO, M. A. C. de P.
700 1 $aSA, M. E. L.
700 1 $aDEAL, R.
700 1 $aRAGOUSSIS, I.
700 1 $aGRATTAPAGLIA, D.
700 1 $aRECH FILHO, E. L.
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Registro original: |
Embrapa Cerrados (CPAC) |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Mandioca e Fruticultura. Para informações adicionais entre em contato com cnpmf.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Mandioca e Fruticultura. |
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Data corrente: |
25/11/2021 |
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Data da última atualização: |
25/11/2021 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 2 |
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Autoria: |
PAIXÃO, J. A. da; ARAÚJO NETO, J. F. de; NASCIMENTO, B. O. do; COSTA, D. M. da; BRANDÃO, H. N.; SOUZA, F. V. D.; SOUZA, E. H. de; ALVES, Q. L.; ERLING, S. B. L.; DAVID, J. P. de L. |
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Afiliação: |
JULIANA AZEVEDO DA PAIXÃO, UFBA; JOSÉ FERNANDO DE ARAÚJO NETO, UFBA; BRUNA OLIVEIRA DO NASCIMENTO, UFBA; DIEGO MOTA DA COSTA, UEFS; HUGO NEVES BRANDÃO, UEFS; FERNANDA VIDIGAL DUARTE SOUZA, CNPMF; EVERTON HILO DE SOUZA, UFRB; QUIARA LOVATTI ALVES, FIOCRUZ; SAMILE BARRETO LIMA ERLING, UNIJORGE; JUCENI PEREIRA DE LIMA DAVID, UFBA. |
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Título: |
Phharmacological actions of ananas comosus l. merril: revision of the works published from 1966 to 2020. |
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Ano de publicação: |
2021 |
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Fonte/Imprenta: |
Pharmacognosy Reviews, v. 15, Issue 29, Jan./Jun., 2021. |
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ISSN: |
0973-7847 |
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Idioma: |
Inglês |
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Conteúdo: |
Bromeliaceae family is very common in Brazilian territory, with approximately 56 genera registered. Ananas comosus (L.) Merr, known as pineapple, one of the most consumed tropical fruits in the world, is the most studied species among them. Additionally some of the plants in this family are used to treat several pathologies in traditional medicine, so this study synthesize the main pharmacological or biological actions of A. comosus and its varieties. A literature review was conducted from the main indexed databases (PubMed, SciELO, Science Direct, Lilacs) about the biological activities of the species A. comosus and its varieties. The Ananas comosus var. comosus was the most cited in the research, we found different secondary metabolites, mainly flavonoids, phenolic compounds and also the complex of enzymes bromelain which were mainly responsible for the fifteen pharmacological activities found, such as abortive, antioxidant activity, hypolipidemic and hypoglycemic. The results obtained in this work show that the species presents several pharmacological applications that can be exploited as a source for new chemical and biological studies that lead to the isolation of promising substances |
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Thesagro: |
Abacaxi. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 01970naa a2200253 a 4500
001 2136551
005 2021-11-25
008 2021 bl uuuu u00u1 u #d
022 $a0973-7847
100 1 $aPAIXÃO, J. A. da
245 $aPhharmacological actions of ananas comosus l. merril$brevision of the works published from 1966 to 2020.$h[electronic resource]
260 $c2021
520 $aBromeliaceae family is very common in Brazilian territory, with approximately 56 genera registered. Ananas comosus (L.) Merr, known as pineapple, one of the most consumed tropical fruits in the world, is the most studied species among them. Additionally some of the plants in this family are used to treat several pathologies in traditional medicine, so this study synthesize the main pharmacological or biological actions of A. comosus and its varieties. A literature review was conducted from the main indexed databases (PubMed, SciELO, Science Direct, Lilacs) about the biological activities of the species A. comosus and its varieties. The Ananas comosus var. comosus was the most cited in the research, we found different secondary metabolites, mainly flavonoids, phenolic compounds and also the complex of enzymes bromelain which were mainly responsible for the fifteen pharmacological activities found, such as abortive, antioxidant activity, hypolipidemic and hypoglycemic. The results obtained in this work show that the species presents several pharmacological applications that can be exploited as a source for new chemical and biological studies that lead to the isolation of promising substances
650 $aAbacaxi
700 1 $aARAÚJO NETO, J. F. de
700 1 $aNASCIMENTO, B. O. do
700 1 $aCOSTA, D. M. da
700 1 $aBRANDÃO, H. N.
700 1 $aSOUZA, F. V. D.
700 1 $aSOUZA, E. H. de
700 1 $aALVES, Q. L.
700 1 $aERLING, S. B. L.
700 1 $aDAVID, J. P. de L.
773 $tPharmacognosy Reviews$gv. 15, Issue 29, Jan./Jun., 2021.
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Embrapa Mandioca e Fruticultura (CNPMF) |
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