Data/hora: 23/06/2024 23:26:28

Biblioteca(s): 	Embrapa Meio Ambiente.	
Data corrente: 	19/01/2017	
Data da última atualização: 	19/10/2020	
Autoria: 	FUKUSHIMA, H. C. S.; LEAL, C. A. G.; CAVALCANTE, R. B.; FIGUEIREDO, H. C. P.; ARIJO, S.; MORIÑIGO, M. A.; ISHIKAWA, M. M.; BORRA, R. C.; RANZANI-PAIVA, M. J. T.	
Afiliação: 	HIRLA COSTA SILVA FUKUSHIMA, FCAV-UNESP; CARLOS AUGUSTO GOMES LEAL, UFMG; RAISSA BERTONCELLO CAVALCANTE, Instituto de Pesca - APTA; HENRIQUE CESAR PEREIRA FIGUEIREDO, UFMG; SALVADOR ARIJO, Universidad de Málaga; MIGUEL ANGEL MORINIGO, Universidad de Málaga; MARCIA MAYUMI ISHIKAWA, CNPMA; RICARDO CARNEIRO BORRA, UFSCar; MARIA JOSE TAVARES RANZANI-PAIVA, Instituto de Pesca - APTA.	
Título: 	Lactococcus garvieae outbreaks in Brazilian farms Lactococcosis in Pseudoplatystoma sp.: development of an autogenous vaccine as a control strategy.	
Ano de publicação: 	2017	
Fonte/Imprenta: 	Journal of Fish Diseases, Oxford, v. 40, n. 2, p. 263-272, 2017.	
DOI: 	dx.doi.org/10.1111/jfd.12509	
Idioma: 	Inglês	
Conteúdo: 	Abstract: This study evaluated the control of streptococcosis outbreaks in Brazil, isolated from diseased sorubim and identified as Lactococcus garvieae by genetic sequencing. This report determined the potential for lactococcosis control in sorubim Pseudoplatystoma sp. with two vaccines: an aqueous-based, whole-cell inactivated vaccine (bacterin) and an oil-adjuvanted bacterin. Their efficacy was evaluated at 30 days post-vaccination (d.p.v.) by challenge with L. garvieae, and the antibody production response at 15, 30 and 60 d.p.v. and the non-specific immune response were compared amongst treatments. High protection levels (P < 0.05) were achieved with the oil-adjuvanted vaccine with a relative percentage survival value of 81.7% at 30 d.p.v. Additionally, the oil-adjuvanted vaccine increased the immunogenicity of the bacterin as indicated by greater agglutination antibody titres from 15 until 60 d.p.v. This is the first report of a positive effect of vaccine administration on the specific immunity of sorubim, and the study showed that a specific antibody plays an important role in sorubim defence against lactococcosis because the innate immune responses were similar in all of the studied animals. These results demonstrated that oil-adjuvanted vaccine can be an effective alternative for the protection of sorubim from L. garvieae disease.	
Palavras-Chave: 	Koch's postulate; Molecular diagnosis.	
Thesagro: 	Bacteriose; Doença animal; Imunologia; Peixe de água doce; Surubim; Vacina inativada; Vacina oleosa.	
Thesaurus Nal: 	Aquaculture; Bacterial vaccines; Freshwater fish; Immunology; Inactivated vaccines; Lactococcus garvieae; Pseudoplatystoma reticulatum.	
Categoria do assunto: 	H Saúde e Patologia	
Registro original: 	Embrapa Meio Ambiente (CNPMA)	
Exemplares: 	CNPMA - (15217-1) - UPC - AP - DD -  -  -  - DIS