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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
14/12/1999 |
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Data da última atualização: |
12/07/2023 |
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Autoria: |
SPENCER, R. R.; PARKER, R. R. |
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Título: |
Rocky mountain spotted fever: infectivity of fasting and recently fed ticks. |
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Ano de publicação: |
1923 |
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Fonte/Imprenta: |
Public Health Report, v. 38, n. 8, p. 333-339, Feb., 1923. |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract : A careful series of experiments with healthy guineapigs was carried out to determine the relative values of inoculation of the macerated tick contents and feeding as a means of conveying Rocky Mountain fever. The criterion of infection was the development of the disease in the animal, or causation of immunity. The results showed that it was unwise to rely either on feeding or inoculation alone, but the latter method is reliable if tested with recently fed ticks, that is, when the virus has been " reactivated." An infected fed tick contains virulent fever-producing virus, while the unfed infected ticks contain a non-virulent immunity-producing virus. This fact explains the comparatively small number of human cases, and the long period of attachment which is usually necessary to cause infection. It also suggests the possibility that the virus may sometimes die out in the tick when unfed for long periods, " reactivation " by ingestion of blood not having taken place. The same loss of virulence occurs in infected eggs which have been dried for four months; these when injected will give rise to immunity but not to fever. P. W. B-S. |
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Palavras-Chave: |
Experimental infection; Experimental transmission; Infectivity; Metastigmata; Tickborne diseases. |
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Thesagro: |
Alimentação; Carrapato; Febre; Infecção. |
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Thesaurus Nal: |
Animal disease models; Animal models; Guinea pigs; Human diseases; Rocky Mountain spotted fever; Virulence. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02020naa a2200313 a 4500
001 1524055
005 2023-07-12
008 1923 bl uuuu u00u1 u #d
100 1 $aSPENCER, R. R.
245 $aRocky mountain spotted fever$binfectivity of fasting and recently fed ticks.
260 $c1923
520 $aAbstract : A careful series of experiments with healthy guineapigs was carried out to determine the relative values of inoculation of the macerated tick contents and feeding as a means of conveying Rocky Mountain fever. The criterion of infection was the development of the disease in the animal, or causation of immunity. The results showed that it was unwise to rely either on feeding or inoculation alone, but the latter method is reliable if tested with recently fed ticks, that is, when the virus has been " reactivated." An infected fed tick contains virulent fever-producing virus, while the unfed infected ticks contain a non-virulent immunity-producing virus. This fact explains the comparatively small number of human cases, and the long period of attachment which is usually necessary to cause infection. It also suggests the possibility that the virus may sometimes die out in the tick when unfed for long periods, " reactivation " by ingestion of blood not having taken place. The same loss of virulence occurs in infected eggs which have been dried for four months; these when injected will give rise to immunity but not to fever. P. W. B-S.
650 $aAnimal disease models
650 $aAnimal models
650 $aGuinea pigs
650 $aHuman diseases
650 $aRocky Mountain spotted fever
650 $aVirulence
650 $aAlimentação
650 $aCarrapato
650 $aFebre
650 $aInfecção
653 $aExperimental infection
653 $aExperimental transmission
653 $aInfectivity
653 $aMetastigmata
653 $aTickborne diseases
700 1 $aPARKER, R. R.
773 $tPublic Health Report$gv. 38, n. 8, p. 333-339, Feb., 1923.
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| 1. |  | PELEGRINI, P. B.; MURAD, A. M.; GROSSI-DE-SÁ, M. F.; MELLO, L. V.; ROMEIRO, L. A. S.; NORONHA, E. F.; CALDAS, R. A; FRANCO, O. L. Structure and enzyme properties of Zabrotes subfasciatus alfa-amylase. Archives of Insect Biochemistry and Physiology, v. 61, p. 77-86, 2006.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: -- - A |
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