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Registro Completo |
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Biblioteca(s): |
Embrapa Pantanal. |
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Data corrente: |
11/09/1997 |
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Data da última atualização: |
11/09/1997 |
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Autoria: |
SILVA, R. A. M. S.; HERRERA, H. M.; DAVILA, A. M. R.; RAMIREZ, L.; PEREIRA, M. E. B. |
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Afiliação: |
EMBRAPA. Centro de Pesquisa Agropecuaria do Pantanal (Corumba, MS); UFMS. Centro Universitario de Corumba (Corumba, MS). |
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Título: |
Pathogenesis of Trypanosoma evansi infection in dogs and horses: light microscopic studies on erythrocyte pathologic changes. |
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Ano de publicação: |
1995 |
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Fonte/Imprenta: |
Memorias do Instituto Oswaldo Cruz, Rio de Janeiro, v.90, p.299, 1995. Suplemento I. |
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Idioma: |
Inglês |
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Conteúdo: |
Trypanosomosis continue to be a problem to human beings and domestic animals in Africa and South America. Effort at control have been only minimally successful, and several areas of the complex disease process remain unclear. Anemia is one of the most consistent findings in trypanosomosis. The nature of the anemia is not completely elucidated and several mechanisms have been proposed including increased red cell destruction, extravascular and intravascular hemolysis by immune (trypanosome antigen/antibody complex and antierythrocyte antibodies), hemolysins, nonspecific phagocytosis activation, direct traumatic effect of trypanosomes, microangiopathy associated with disseminated intravascular coagulation (DIC), splenic phagocytosis and splenic pooling, increased plasma volume, noncompensatory and/or decreased erythropoiesis and anemia of chronic disorders. In the present study, light microscopy were used to investigate aspects of erythrocite pathologic changes in dogs and horses naturally infected by T. evansi. Thin blood films stained with May Gruwald-Giemsa from ten horses and four dogs naturally infected with T. evansi were examined for morphologic abnormalities of erytrocytes. Several erytrocytes abnormalities were observed in the blood of infected dogs and horses. These included the appearance of microspherocytes, acanthocytes, dacrocytes, codocytes, vacuolated, and sometimes bizarre shapes. Polychromasia and poikilocytosis were present in both dogs and horse erythrocytes. Adhesion of erythrocytes to trypanosomes in circulanting blood and erythrophagocytosis were also observed. The adhesion phenomenon has also been demonstrated in T. gambiense, T. rhodesiense, T. brucei, T. congolense and T. lewisi. The adhesion may damage the erythrocyte through alterations of membrane and to predispose to destruction of the affected red cell. Erythrophagocytosis demonstrated in our study with light microscopy has also been observed in various infections by other trypanosome species. We conclude that erythrocyte abnormalities, trypanosome adhesion to red cells and erythrophagocytosis are important cause of anemia in trypanosomosis due to T. evansi in dogs and horses. MenosTrypanosomosis continue to be a problem to human beings and domestic animals in Africa and South America. Effort at control have been only minimally successful, and several areas of the complex disease process remain unclear. Anemia is one of the most consistent findings in trypanosomosis. The nature of the anemia is not completely elucidated and several mechanisms have been proposed including increased red cell destruction, extravascular and intravascular hemolysis by immune (trypanosome antigen/antibody complex and antierythrocyte antibodies), hemolysins, nonspecific phagocytosis activation, direct traumatic effect of trypanosomes, microangiopathy associated with disseminated intravascular coagulation (DIC), splenic phagocytosis and splenic pooling, increased plasma volume, noncompensatory and/or decreased erythropoiesis and anemia of chronic disorders. In the present study, light microscopy were used to investigate aspects of erythrocite pathologic changes in dogs and horses naturally infected by T. evansi. Thin blood films stained with May Gruwald-Giemsa from ten horses and four dogs naturally infected with T. evansi were examined for morphologic abnormalities of erytrocytes. Several erytrocytes abnormalities were observed in the blood of infected dogs and horses. These included the appearance of microspherocytes, acanthocytes, dacrocytes, codocytes, vacuolated, and sometimes bizarre shapes. Polychromasia and poikilocytosis were present in both dogs and horse erythrocyte... Mostrar Tudo |
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Palavras-Chave: |
Cachorro; Dog; Horse. |
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Thesagro: |
Cavalo. |
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Thesaurus Nal: |
Trypanosoma evansi. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02882naa a2200229 a 4500
001 1791638
005 1997-09-11
008 1995 bl uuuu u00u1 u #d
100 1 $aSILVA, R. A. M. S.
245 $aPathogenesis of Trypanosoma evansi infection in dogs and horses$blight microscopic studies on erythrocyte pathologic changes.
260 $c1995
520 $aTrypanosomosis continue to be a problem to human beings and domestic animals in Africa and South America. Effort at control have been only minimally successful, and several areas of the complex disease process remain unclear. Anemia is one of the most consistent findings in trypanosomosis. The nature of the anemia is not completely elucidated and several mechanisms have been proposed including increased red cell destruction, extravascular and intravascular hemolysis by immune (trypanosome antigen/antibody complex and antierythrocyte antibodies), hemolysins, nonspecific phagocytosis activation, direct traumatic effect of trypanosomes, microangiopathy associated with disseminated intravascular coagulation (DIC), splenic phagocytosis and splenic pooling, increased plasma volume, noncompensatory and/or decreased erythropoiesis and anemia of chronic disorders. In the present study, light microscopy were used to investigate aspects of erythrocite pathologic changes in dogs and horses naturally infected by T. evansi. Thin blood films stained with May Gruwald-Giemsa from ten horses and four dogs naturally infected with T. evansi were examined for morphologic abnormalities of erytrocytes. Several erytrocytes abnormalities were observed in the blood of infected dogs and horses. These included the appearance of microspherocytes, acanthocytes, dacrocytes, codocytes, vacuolated, and sometimes bizarre shapes. Polychromasia and poikilocytosis were present in both dogs and horse erythrocytes. Adhesion of erythrocytes to trypanosomes in circulanting blood and erythrophagocytosis were also observed. The adhesion phenomenon has also been demonstrated in T. gambiense, T. rhodesiense, T. brucei, T. congolense and T. lewisi. The adhesion may damage the erythrocyte through alterations of membrane and to predispose to destruction of the affected red cell. Erythrophagocytosis demonstrated in our study with light microscopy has also been observed in various infections by other trypanosome species. We conclude that erythrocyte abnormalities, trypanosome adhesion to red cells and erythrophagocytosis are important cause of anemia in trypanosomosis due to T. evansi in dogs and horses.
650 $aTrypanosoma evansi
650 $aCavalo
653 $aCachorro
653 $aDog
653 $aHorse
700 1 $aHERRERA, H. M.
700 1 $aDAVILA, A. M. R.
700 1 $aRAMIREZ, L.
700 1 $aPEREIRA, M. E. B.
773 $tMemorias do Instituto Oswaldo Cruz, Rio de Janeiro$gv.90, p.299, 1995. Suplemento I.
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Registro original: |
Embrapa Pantanal (CPAP) |
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| Registros recuperados : 8 | |
| 1. |  | SILVA, R. A. M. S.; DAVILA, A. M. R.; PEREIRA, M. E. B.; RAMIREZ, L.; SANCHES, W.; GUTIERREZ, J. L. Bovine trypanosomiasis due to Trypanosoma vivax in the German Bush province, Bolivia. Memorias do Instituto Oswaldo Cruz, v.92, p.124, Nov. 1997. Supplement 1.| Biblioteca(s): Embrapa Pantanal. |
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| 7. | | SILVA, R. A. M. S.; SILVA, J. A. da; SCHENEIDER, R. C.; FREITAS, J. de; MESQUITA, D. P.; MESQUITA, T. C.; RAMIREZ, L.; DAVILA, A. M. R.; PEREIRA, M. E. B. Bovine trypanosomosis due to Trypanosoma vivax in the northern subregion of Pantanal, Brazil. Trypnews, v.2, n.4, p.1-2, Dec. 1995.| Biblioteca(s): Embrapa Pantanal. |
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| 8. | | SILVA, R. A. M. S.; SILVA, J. A. da; SCHNEIDER, R. C.; FREITAS, J. de; MESQUITA, D.; MESQUITA, T.; RAMIREZ, L.; RIVERA DAVILA, A. M.; PEREIRA, M. E. B. Outbreak of Trypanosomiasis due to Trypanosoma vivax (Ziemann, 1905) in bovines of the Pantanal, Brazil. Memorias Instituto Oswaldo Cruz, Rio de Janeiro, v.91, n.5, p.561-562, 1996.| Biblioteca(s): Embrapa Pantanal. |
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| Registros recuperados : 8 | |
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