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 | Acesso ao texto completo restrito à biblioteca da Embrapa Instrumentação. Para informações adicionais entre em contato com cnpdia.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Instrumentação. |
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Data corrente: |
09/12/2015 |
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Data da última atualização: |
31/07/2018 |
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Tipo da produção científica: |
Artigo em Anais de Congresso |
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Autoria: |
PEREIRA, M. F. L.; CRUVINEL, P. E. |
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Afiliação: |
PAULO ESTEVAO CRUVINEL, SGE. |
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Título: |
Ferramenta de visualização tridimensional de amostras indeformadas de solo agrícolas obtidas com a técnica de tomografia de raios-x. |
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Ano de publicação: |
2015 |
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Fonte/Imprenta: |
In: CONGRESSO BRASILEIRO DE AGROINFORMÁTICA, 10., 2015, Ponta Grossa. [Anais...] Viçosa: SBIAGRO, 2015. |
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Idioma: |
Português |
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Palavras-Chave: |
Evento. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 00508nam a2200121 a 4500
001 2031249
005 2018-07-31
008 2015 bl uuuu u00u1 u #d
100 1 $aPEREIRA, M. F. L.
245 $aFerramenta de visualização tridimensional de amostras indeformadas de solo agrícolas obtidas com a técnica de tomografia de raios-x.$h[electronic resource]
260 $aIn: CONGRESSO BRASILEIRO DE AGROINFORMÁTICA, 10., 2015, Ponta Grossa. [Anais...] Viçosa: SBIAGRO$c2015
653 $aEvento
700 1 $aCRUVINEL, P. E.
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Embrapa Instrumentação (CNPDIA) |
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Biblioteca(s): |
Embrapa Pecuária Sul; Embrapa Pesca e Aquicultura; Embrapa Recursos Genéticos e Biotecnologia. |
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Data corrente: |
14/07/2014 |
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Data da última atualização: |
13/03/2023 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
SOUZA, C. J. H. de; McNEILLY, A. S.; BENAVIDES, M. V.; MELO, E. O.; MORAES, J. C. F. |
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Afiliação: |
CARLOS JOSE HOFF DE SOUZA, CNPASA; A. S. McNeilly, University of Edinburgh; MAGDA VIEIRA BENAVIDES, SRI; EDUARDO DE OLIVEIRA MELO, CENARGEN; JOSE CARLOS FERRUGEM MORAES, CPPSUL. |
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Título: |
Mutation in the protease cleavage site of GDF9 increases ovulation rate and litter size in heterozygous ewes and causes infertility in homozygous ewes. |
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Ano de publicação: |
2014 |
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Fonte/Imprenta: |
Animal Genetics, Oxford, v. 45, n. 5, p. 732-739, Oct. 2014. |
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DOI: |
10.1111/age.12190 |
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Idioma: |
Inglês |
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Conteúdo: |
Litter size (LS) in sheep is determined mainly by ovulation rate (OR). Several polymorphisms have been identified in the growth differentiation factor 9 (GDF9) gene that result in an increase in OR and prolificacy of sheep. Screening the databank of the Brazilian Sheep Breeders Association for triplet delivery, we identified flocks of prolific Ile de France ewes. After resequencing of GDF9, a point mutation (c.943C>T) was identified, resulting in a nonconservative amino acid change (p.Arg315Cys) in the cleavage site of the propeptide. This new allele was called Vacaria (FecGv). A flock of half-sib ewes was evaluated for OR in the first three breeding seasons, and Vacaria heterozygotes had higher OR (P < 0.001), averaging 2.1 +- 0.1 when compared to 1.2 +- 0.1 in wild-type ewes. The OR was also influenced by age, increasing in the second and third breeding seasons (P < 0.001). In flocks segregating this allele, the LS was higher in mutant sheep (P < 0.001), averaging 1.61 +- 0.07 in heterozygotes and 1.29 +- 0.03 in wild-type ewes. Analysis of homozygote reproductive tract morphology revealed uterine and ovarian hypoplasia. Ovarian follicles continue to develop up to small antral stages, although with abnormal oocyte morphology and altered arrangement of granulosa cells. After the collapse of the oocyte in most follicles, the remaining cells formed clusters that persisted in the ovary. This SNP is useful to improve selection for dam prolificacy and also as a model to investigate GDF9 post-translation processing and the fate of the follicular cells that remain after the oocyte demise. MenosLitter size (LS) in sheep is determined mainly by ovulation rate (OR). Several polymorphisms have been identified in the growth differentiation factor 9 (GDF9) gene that result in an increase in OR and prolificacy of sheep. Screening the databank of the Brazilian Sheep Breeders Association for triplet delivery, we identified flocks of prolific Ile de France ewes. After resequencing of GDF9, a point mutation (c.943C>T) was identified, resulting in a nonconservative amino acid change (p.Arg315Cys) in the cleavage site of the propeptide. This new allele was called Vacaria (FecGv). A flock of half-sib ewes was evaluated for OR in the first three breeding seasons, and Vacaria heterozygotes had higher OR (P < 0.001), averaging 2.1 +- 0.1 when compared to 1.2 +- 0.1 in wild-type ewes. The OR was also influenced by age, increasing in the second and third breeding seasons (P < 0.001). In flocks segregating this allele, the LS was higher in mutant sheep (P < 0.001), averaging 1.61 +- 0.07 in heterozygotes and 1.29 +- 0.03 in wild-type ewes. Analysis of homozygote reproductive tract morphology revealed uterine and ovarian hypoplasia. Ovarian follicles continue to develop up to small antral stages, although with abnormal oocyte morphology and altered arrangement of granulosa cells. After the collapse of the oocyte in most follicles, the remaining cells formed clusters that persisted in the ovary. This SNP is useful to improve selection for dam prolificacy and also as a model to investig... Mostrar Tudo |
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Thesagro: |
Fecundação; Fecundação animal; Ovino; Parto; Reprodução animal. |
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Thesaurus NAL: |
Ewes; Fecundity; Multiple births. |
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Categoria do assunto: |
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L Ciência Animal e Produtos de Origem Animal |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/180001/1/Souza-et-al-2014-Animal-Genetics.pdf
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/109667/1/age12190.pdf
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Marc: |
LEADER 02469naa a2200277 a 4500
001 1998487
005 2023-03-13
008 2014 bl uuuu u00u1 u #d
024 7 $a10.1111/age.12190$2DOI
100 1 $aSOUZA, C. J. H. de
245 $aMutation in the protease cleavage site of GDF9 increases ovulation rate and litter size in heterozygous ewes and causes infertility in homozygous ewes.$h[electronic resource]
260 $c2014
520 $aLitter size (LS) in sheep is determined mainly by ovulation rate (OR). Several polymorphisms have been identified in the growth differentiation factor 9 (GDF9) gene that result in an increase in OR and prolificacy of sheep. Screening the databank of the Brazilian Sheep Breeders Association for triplet delivery, we identified flocks of prolific Ile de France ewes. After resequencing of GDF9, a point mutation (c.943C>T) was identified, resulting in a nonconservative amino acid change (p.Arg315Cys) in the cleavage site of the propeptide. This new allele was called Vacaria (FecGv). A flock of half-sib ewes was evaluated for OR in the first three breeding seasons, and Vacaria heterozygotes had higher OR (P < 0.001), averaging 2.1 +- 0.1 when compared to 1.2 +- 0.1 in wild-type ewes. The OR was also influenced by age, increasing in the second and third breeding seasons (P < 0.001). In flocks segregating this allele, the LS was higher in mutant sheep (P < 0.001), averaging 1.61 +- 0.07 in heterozygotes and 1.29 +- 0.03 in wild-type ewes. Analysis of homozygote reproductive tract morphology revealed uterine and ovarian hypoplasia. Ovarian follicles continue to develop up to small antral stages, although with abnormal oocyte morphology and altered arrangement of granulosa cells. After the collapse of the oocyte in most follicles, the remaining cells formed clusters that persisted in the ovary. This SNP is useful to improve selection for dam prolificacy and also as a model to investigate GDF9 post-translation processing and the fate of the follicular cells that remain after the oocyte demise.
650 $aEwes
650 $aFecundity
650 $aMultiple births
650 $aFecundação
650 $aFecundação animal
650 $aOvino
650 $aParto
650 $aReprodução animal
700 1 $aMcNEILLY, A. S.
700 1 $aBENAVIDES, M. V.
700 1 $aMELO, E. O.
700 1 $aMORAES, J. C. F.
773 $tAnimal Genetics, Oxford$gv. 45, n. 5, p. 732-739, Oct. 2014.
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