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Registro Completo |
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Biblioteca(s): |
Embrapa Unidades Centrais. |
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Data corrente: |
10/03/2016 |
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Data da última atualização: |
10/03/2016 |
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Autoria: |
CAGNINI, D. Q.; CUNHA, P. H. J.; PANTOJA, J. C. F.; BADIAL, P. R.; OLIVEIRA-FILHO, J. P. de; ARAÚJO-JUNIOR, J. P.; ALFIERI, A. A.; BORGES, A. S. |
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Afiliação: |
DIDIER Q. CAGNINI, FMVZ/UNESP; PAULO H. J. CUNHA, UFG; JOSÉ C. F. PANTOJA, FMVZ/UNESP; PERES R. BADIAL, FMVZ/UNESP; JOSÉ PAES DE OLIVEIRA-FILHO, FMVZ/UNESP; JOÃO P. ARAÚJO-JUNIOR, UNESP; AMAURI A. ALFIERI, UNESP; ALEXANDRE S. BORGES, FMVZ/UNESP. |
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Título: |
Histopathological, immunohistochemical, and molecular study of BHV-5 infection in the central nervous system of experimentally infected calves. |
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Ano de publicação: |
2015 |
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Fonte/Imprenta: |
Pesquisa Veterinária Brasileira, Brasília, DF, v. 35. n. 4, p. 337-343, abr. 2015. |
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Idioma: |
Inglês |
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Conteúdo: |
Bovine meningoencephalitis caused by BHV-5, a double-stranded DNA enveloped virus that belongs to the family Herpesviridae and subfamily Alphaherpesvirinae, is an important differential diagnosis of central nervous diseases. The aim of this study was to describe the histological changes in the central nervous system of calves experimentally infected with BHV-5 and compare these changes with the PCR and IHC results. Formalin-fixed paraffin--embedded central nervous system samples from calves previously inoculated with BHV-5 were microscopically evaluated and tested using IHC and PCR. All the animals presented with nonsuppurative meningoencephalitis. From 18 evaluated areas of each calf, 32.41% and 35.19% were positive by IHC and PCR, respectively. The telencephalon presented more accentuated lesions and positive areas in the PCR than other encephalic areas and was the best sampling area for diagnostic purposes. Positive areas in the IHC and PCR were more injured than IHC and PCR negative areas. The animal with neurological signs showed more PCR- and IHC-positive areas than the other animals. |
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Palavras-Chave: |
Disease of cattle; Herpesvirus bovino 5; Meningoencefalite; Neuropatologia. |
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Thesagro: |
Bovino; Doença. |
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Thesaurus Nal: |
Bovine herpesvirus 5; Meningoencephalitis; Neuropathology. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/140970/1/Histopathological-immunohistochemical.pdf
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Marc: |
LEADER 02082naa a2200313 a 4500
001 2040471
005 2016-03-10
008 2015 bl uuuu u00u1 u #d
100 1 $aCAGNINI, D. Q.
245 $aHistopathological, immunohistochemical, and molecular study of BHV-5 infection in the central nervous system of experimentally infected calves.
260 $c2015
520 $aBovine meningoencephalitis caused by BHV-5, a double-stranded DNA enveloped virus that belongs to the family Herpesviridae and subfamily Alphaherpesvirinae, is an important differential diagnosis of central nervous diseases. The aim of this study was to describe the histological changes in the central nervous system of calves experimentally infected with BHV-5 and compare these changes with the PCR and IHC results. Formalin-fixed paraffin--embedded central nervous system samples from calves previously inoculated with BHV-5 were microscopically evaluated and tested using IHC and PCR. All the animals presented with nonsuppurative meningoencephalitis. From 18 evaluated areas of each calf, 32.41% and 35.19% were positive by IHC and PCR, respectively. The telencephalon presented more accentuated lesions and positive areas in the PCR than other encephalic areas and was the best sampling area for diagnostic purposes. Positive areas in the IHC and PCR were more injured than IHC and PCR negative areas. The animal with neurological signs showed more PCR- and IHC-positive areas than the other animals.
650 $aBovine herpesvirus 5
650 $aMeningoencephalitis
650 $aNeuropathology
650 $aBovino
650 $aDoença
653 $aDisease of cattle
653 $aHerpesvirus bovino 5
653 $aMeningoencefalite
653 $aNeuropatologia
700 1 $aCUNHA, P. H. J.
700 1 $aPANTOJA, J. C. F.
700 1 $aBADIAL, P. R.
700 1 $aOLIVEIRA-FILHO, J. P. de
700 1 $aARAÚJO-JUNIOR, J. P.
700 1 $aALFIERI, A. A.
700 1 $aBORGES, A. S.
773 $tPesquisa Veterinária Brasileira, Brasília, DF$gv. 35. n. 4, p. 337-343, abr. 2015.
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Registro original: |
Embrapa Unidades Centrais (AI-SEDE) |
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| Registros recuperados : 2 | |
| 1. |  | MANZI, M. P.; JOAQUIM, S. F.; GUIMARÃES, F. F.; BRUDER-NASCIMENTO, A. C. M. O.; PANTOJA, J. C. F.; LANGONI, H. Prevalência de Mycoplasma bovis em rebanhos de vacas leiteiras. Pesquisa Veterinária Brasileira, Rio de Janeiro, v. 38, n. 4, p. 665-669, abril 2018 Título em inglês: Prevalence of Mycoplasma bovis in dairy herds.| Biblioteca(s): Embrapa Unidades Centrais. |
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| 2. | | CAGNINI, D. Q.; CUNHA, P. H. J.; PANTOJA, J. C. F.; BADIAL, P. R.; OLIVEIRA-FILHO, J. P. de; ARAÚJO-JUNIOR, J. P.; ALFIERI, A. A.; BORGES, A. S. Histopathological, immunohistochemical, and molecular study of BHV-5 infection in the central nervous system of experimentally infected calves. Pesquisa Veterinária Brasileira, Brasília, DF, v. 35. n. 4, p. 337-343, abr. 2015.| Biblioteca(s): Embrapa Unidades Centrais. |
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| Registros recuperados : 2 | |
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