Data/hora: 22/06/2024 13:27:27

Biblioteca(s): 	Embrapa Mandioca e Fruticultura.	
Data corrente: 	24/01/2001	
Data da última atualização: 	24/01/2001	
Autoria: 	OGIHARA, T.; OKI, K.; IIDA, Y.; HAYASHI, S. -I.	
Afiliação: 	First Department of Medicine. Department of Pediatrics and. Department of nutrition and physiological Chemistry of Osaka University Medical School, Osaka.	
Título: 	Endemic goiter in sarawak, Borneo Island; prevalence and Pathogenesis	
Ano de publicação: 	1972	
Fonte/Imprenta: 	Endocrinol. Japon., v.19, n.3, p.285-293, June-1972.	
Idioma: 	Inglês	
Conteúdo: 	A survey for endemic goiter was carried out on Iban natives (Sea Dayak) in four districts along the Rajang River in Sarawak, Borneo Island. Among 608 subjects (271 males and 337 females) examined, 134 subjects (22 males and 112 females) were found to be goitrous, the prevalece of goiter being 8.1% for male and 33.2% for male. None were clinically hypo-or hypethyroid, no cretinism was dected. Twenty-four hr. thyroidal I-uptake was 54.3 = 13.1% (mean = S.D.) in goitrous subjects while 47.1=10.2% in non-goitrous (no statistical significance). Urinary excretion of iodine was 45 = 27 ug per day in groitrous group and 49 = 25 ug in nongoitrous group (no significance). Iodone content of drinking water was extremely low in ali four districts, the lowest one being obtained from region in wich the prevalence of goiter is highest. Thyroid parameters such as PBI, T3 resin sponge uptake and cholesterol were all within normal limits. Anti-thyroid antibodies were not demonstrared in sera from either goitrous or nongoitrous subjects. KSCN discharge test was positive in two cases in a single family, among 33 cases studied. Experimental feeding of cassava on our expedition members for two weeks did not show any change in thyroid  parametrs including KSCN discharge test. It is thought that iodine deficiency is probably a major causative factor of endemic goiter in Sarawak, Borneo Island. Other factors such as organification defect or defective thyroxine binding proteins might have some role in individual cases.                         	
Palavras-Chave: 	Disease; Efeito; Effect; Goitre; Thyroid.	
Thesagro: 	Bócio; Doença; Mandioca; Tireóide.	
Thesaurus Nal: 	cassava.	
Categoria do assunto: 	--	
Registro original: 	Embrapa Mandioca e Fruticultura (CNPMF)	
Exemplares: 	CNPMF - (18882-1) - ADD - SP - -- - S1811 -  - S1811 - DIS