Data/hora: 10/06/2024 09:59:47

Biblioteca(s): | Embrapa Caprinos e Ovinos.
Data corrente: | 23/06/2017
Data da última atualização: | 23/06/2017
Autoria: | MANN, G. E.; CAMPBELL, B. K.; McNEILLY, A. S.; BAIRD, D. T.
Título: | Effects of passively immunizing ewes against inhibin and oestradiol during the follicular phase of the oestrous cycle.
Ano de publicação: | 1990
Fonte/Imprenta: | Journal of Endocrinology, v. 125, n. 3, p. 417-424, Jun. 1990.
Idioma: | Inglês
Conteúdo: | Abstract: Passive immunization was used to investigate the importance of inhibin and oestradiol in the control of FSH production during the follicular phase of the oestrous cycle in the sheep. Four groups of five mature Scottish Blackface ewes were injected with normal sheep plasma (control), antiserum to the 1-26 alpha peptide fragment of porcine inhibin, antiserum to oestradiol-17 beta, or a combination of the two antisera, 24 h following cloprostenol-induced luteal regression. There was no difference in the concentration of LH in jugular venous plasma between the control and inhibin-immunized groups following the injection of normal sheep plasma or inhibin antiserum, with both groups exhibiting normal LH surges. In both the groups immunized against oestradiol, the basal concentration of LH rose by 25-30% (P less than 0.05) during the 96-h period following injection, while the LH surge and consequent formation of a corpus luteum was inhibited. In all three immunized groups there was a significant (P less than 0.001) rise in the concentration of FSH starting 3.8-4.8 h after the injection of antiserum. The duration of the rise was similar in the groups injected with oestradiol antiserum alone (43.6 +/- 12.8 h) or in combination with inhibin antiserum (40.6 +/- 11.7 h), but was significantly (P less than 0.05) shorter in the group immunized against inhibin alone
Palavras-Chave: | Drug effects; FSH; Inhibins; Inhibition; LH.
Thesagro: | Estradiol.
Thesaurus Nal: | Blood; cloprostenol; Ovulation; Pharmacology; Physiology; Progesterone; Sheep.
Categoria do assunto: | L Ciência Animal e Produtos de Origem Animal
Registro original: | Embrapa Caprinos e Ovinos (CNPC)
Exemplares: | CNPC - (33929-1) - ADD - AP - PP -  -  -  - DIS