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Registro Completo |
Biblioteca(s): |
Embrapa Gado de Leite. |
Data corrente: |
15/09/2021 |
Data da última atualização: |
15/09/2021 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
PEREIRA, H. P.; VERARDO, L. L.; WELLER, M. M. D. C. A.; SBARDELLA, A. P.; MUNARI, D. P.; DAIBERT, R. M. de P.; CARVALHO, W. A.; MACHADO, M. A.; MARTINS, M. F. |
Afiliação: |
HYAGO PASSE PEREIRA, Universidade Federal de Juiz de Fora; LUCAS LIMA VERARDO, Universidade Federal dos Vales do Jequitinhonha e Mucuri; MAYARA MORENA DEL CAMBRE AMARAL WELLER, Universidade Federal do Espírito Santo; ANA PAULA SBARDELLA, Universidade Estadual Paulista Júlio de Mesquita Filho; DANÍSIO PRADO MUNARI, Universidade Estadual Paulista Júlio de Mesquita Filho; RAQUEL MORAIS DE PAIVA DAIBERT; WANESSA ARAUJO CARVALHO, CNPGL; MARCO ANTONIO MACHADO, CNPGL; MARTA FONSECA MARTINS, CNPGL. |
Título: |
Going further post-RNA-seq: in silico functional analyses revealing candidate genes and regulatory elements related to mastitis in dairy cattle. |
Ano de publicação: |
2021 |
Fonte/Imprenta: |
Journal of Dairy Research, v. 88, p. 286-292, 2021. |
Idioma: |
Inglês |
Conteúdo: |
This study aimed to obtain a better understanding of the regulatory genes and molecules involved in the development of mastitis. For this purpose, the transcription factors (TF) and MicroRNAs (miRNA) related to differentially expressed genes previously found in extracorporeal udders infected with Streptococcus agalactiae were investigated. The Gene-TF network highlighted LOC515333, SAA3, CD14, NFKBIA, APOC2 and LOC100335608 and genes that encode the most representative transcription factors STAT3, PPARG, EGR1 and NFKB1 for infected udders. In addition, it was possible to highlight, through the analysis of the gene-miRNA network, genes that could be post-transcriptionally regulated by miRNAs, such as the relationship between the CCL5 gene and the miRNA bta-miR-363. Overall, our data demonstrated genes and regulatory elements (TF and miRNA) that can play an important role in mastitis resistance. The results provide new insights into the first functional pathways and the network of genes that orchestrate the innate immune responses to infection by Streptococcus agalactiae. Our results will increase the general knowledge about the gene networks, transcription factors and miRNAs involved in fighting intramammary infection and maintaining tissue during infection and thus enable a better understanding of the pathophysiology of mastitis. |
Thesagro: |
Bovino; Gado Leiteiro; Mamite. |
Thesaurus Nal: |
Mastitis; MicroRNA; Transcription factors. |
Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
Marc: |
LEADER 02222naa a2200289 a 4500 001 2134430 005 2021-09-15 008 2021 bl uuuu u00u1 u #d 100 1 $aPEREIRA, H. P. 245 $aGoing further post-RNA-seq$bin silico functional analyses revealing candidate genes and regulatory elements related to mastitis in dairy cattle.$h[electronic resource] 260 $c2021 520 $aThis study aimed to obtain a better understanding of the regulatory genes and molecules involved in the development of mastitis. For this purpose, the transcription factors (TF) and MicroRNAs (miRNA) related to differentially expressed genes previously found in extracorporeal udders infected with Streptococcus agalactiae were investigated. The Gene-TF network highlighted LOC515333, SAA3, CD14, NFKBIA, APOC2 and LOC100335608 and genes that encode the most representative transcription factors STAT3, PPARG, EGR1 and NFKB1 for infected udders. In addition, it was possible to highlight, through the analysis of the gene-miRNA network, genes that could be post-transcriptionally regulated by miRNAs, such as the relationship between the CCL5 gene and the miRNA bta-miR-363. Overall, our data demonstrated genes and regulatory elements (TF and miRNA) that can play an important role in mastitis resistance. The results provide new insights into the first functional pathways and the network of genes that orchestrate the innate immune responses to infection by Streptococcus agalactiae. Our results will increase the general knowledge about the gene networks, transcription factors and miRNAs involved in fighting intramammary infection and maintaining tissue during infection and thus enable a better understanding of the pathophysiology of mastitis. 650 $aMastitis 650 $aMicroRNA 650 $aTranscription factors 650 $aBovino 650 $aGado Leiteiro 650 $aMamite 700 1 $aVERARDO, L. L. 700 1 $aWELLER, M. M. D. C. A. 700 1 $aSBARDELLA, A. P. 700 1 $aMUNARI, D. P. 700 1 $aDAIBERT, R. M. de P. 700 1 $aCARVALHO, W. A. 700 1 $aMACHADO, M. A. 700 1 $aMARTINS, M. F. 773 $tJournal of Dairy Research$gv. 88, p. 286-292, 2021.
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Registro original: |
Embrapa Gado de Leite (CNPGL) |
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| Acesso ao texto completo restrito à biblioteca da Embrapa Hortaliças. Para informações adicionais entre em contato com cnph.biblioteca@embrapa.br. |
Registro Completo
Biblioteca(s): |
Embrapa Hortaliças. |
Data corrente: |
06/12/1995 |
Data da última atualização: |
06/12/1995 |
Autoria: |
TOLEDO, L. R. |
Título: |
Nada de exageros [tomate]. |
Ano de publicação: |
1995 |
Fonte/Imprenta: |
Revista Globo Rural, Sao Paulo, v.11, n.122, p.32-35, dez. 1995. |
Idioma: |
Português |
Conteúdo: |
Solucoes para colher tomates ecologicamente corretos e diminuir custos. |
Palavras-Chave: |
Bemisia argentifolli; Control; Controle; Disease; Insect; Pest; Tomato; White fly; Whitefly. |
Thesagro: |
Doença; Inseto; Lycopersicon Esculentum; Mosca Branca; Praga; Tomate. |
Thesaurus NAL: |
Aleyrodidae. |
Categoria do assunto: |
-- |
Marc: |
LEADER 00802naa a2200313 a 4500 001 1754203 005 1995-12-06 008 1995 bl uuuu u00u1 u #d 100 1 $aTOLEDO, L. R. 245 $aNada de exageros [tomate]. 260 $c1995 520 $aSolucoes para colher tomates ecologicamente corretos e diminuir custos. 650 $aAleyrodidae 650 $aDoença 650 $aInseto 650 $aLycopersicon Esculentum 650 $aMosca Branca 650 $aPraga 650 $aTomate 653 $aBemisia argentifolli 653 $aControl 653 $aControle 653 $aDisease 653 $aInsect 653 $aPest 653 $aTomato 653 $aWhite fly 653 $aWhitefly 773 $tRevista Globo Rural, Sao Paulo$gv.11, n.122, p.32-35, dez. 1995.
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