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Biblioteca(s): |
Embrapa Cerrados. |
Data corrente: |
12/12/2018 |
Data da última atualização: |
12/12/2018 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
PERIPOLLI, E.; METZGER, J.; LEMOS, M. V. A. de; STAFUZZA, N. B.; KLUSKA, S.; OLIVIERI, B. F.; FEITOSA, F. L. B.; BERTON, M. P.; LOPES, F. B.; MUNARI, D. P.; LOBO, R. B.; MAGNABOSCO, C. de U.; DI CROCE, F.; OSTERSTOCK, J.; DENISE, S.; PEREIRA, A. S. C.; BALDI, F. |
Afiliação: |
ELISA PERIPOLLI, UNESP; JULIA METZGER, University of Veterinary Medicine Hannover; MARCOS VINICIUS ANTUNES DE LEMOS, UNESP; NEDENIA BONVINOSTAFUZZA, UNESP; SABRINA KLUSKA, UNESP; BIANCA FERREIRA OLIVIERI, UNESP; FABIELI LOUISE BRAGA FEITOSA, UNESP; MARIANA PIATTO BERTON, UNESP; FERNANDO BRITO LOPES, UNESP; DANISIO PRADO MUNARI, UNESP; RAYSILDO BARBOSA LOBO, Associação Nacional de Criadores e Pesquisadores; CLAUDIO DE ULHOA MAGNABOSCO, CPAC; FERNANDO DI CROCE, Zoetis; JASON OSTERSTOCK, Zoetis; SUE DENISE, Zoetis; ANGELICA SIMONE CRAVO PEREIRA, USP; FERNANDO BALDI, UNESP. |
Título: |
Autozygosity islands and ROH patterns in Nellore lineages: evidence of selection for functionally important traits. |
Ano de publicação: |
2018 |
Fonte/Imprenta: |
BMC Genomics, v. 19, 680, 2018. |
DOI: |
https://dx.doi.org/10.1186%2Fs12864-018-5060-8 |
Idioma: |
Inglês |
Conteúdo: |
Abstract Background The aim of this study was to assess genome-wide autozygosity in a Nellore cattle population and to characterize ROH patterns and autozygosity islands that may have occurred due to selection within its lineages. It attempts also to compare estimates of inbreeding calculated from ROH (FROH), genomic relationship matrix (FGRM), and pedigree-based coefficient (FPED). Results The average number of ROH per animal was 55.15 ± 13.01 with an average size of 3.24 Mb. The Nellore genome is composed mostly by a high number of shorter segments accounting for 78% of all ROH, although the proportion of the genome covered by them was relatively small. The genome autozygosity proportion indicates moderate to high inbreeding levels for classical standards, with an average value of 7.15% (178.70 Mb). The average of FPED and FROH, and their correlations (− 0.05 to 0.26) were low. Estimates of correlation between FGRM-FPED was zero, while the correlation (− 0.01 to − 0.07) between FGRM-FROH decreased as a function of ROH length, except for FROH > 8Mb (− 0.03). Overall, inbreeding coefficients were not high for the genotyped animals. Autozygosity islands were evident across the genome (n = 62) and their genomic location did not largely differ within lineages. Enriched terms (p < 0.01) associated with defense response to bacteria (GO:0042742), immune complex reaction (GO:0045647), pregnancy-associated glycoproteins genes (GO:0030163), and organism growth (GO:0040014) were described within the autozygotic islands. Conclusions Low FPED-FROH correlation estimates indicate that FPED is not the most suitable method for capturing ancient inbreeding when the pedigree does not extend back many generations and FROH should be used instead. Enriched terms (p < 0.01) suggest a strong selection for immune response. Non-overlapping islands within the lineages greatly explain the mechanism underlying selection for functionally important traits in Nellore cattle. MenosAbstract Background The aim of this study was to assess genome-wide autozygosity in a Nellore cattle population and to characterize ROH patterns and autozygosity islands that may have occurred due to selection within its lineages. It attempts also to compare estimates of inbreeding calculated from ROH (FROH), genomic relationship matrix (FGRM), and pedigree-based coefficient (FPED). Results The average number of ROH per animal was 55.15 ± 13.01 with an average size of 3.24 Mb. The Nellore genome is composed mostly by a high number of shorter segments accounting for 78% of all ROH, although the proportion of the genome covered by them was relatively small. The genome autozygosity proportion indicates moderate to high inbreeding levels for classical standards, with an average value of 7.15% (178.70 Mb). The average of FPED and FROH, and their correlations (− 0.05 to 0.26) were low. Estimates of correlation between FGRM-FPED was zero, while the correlation (− 0.01 to − 0.07) between FGRM-FROH decreased as a function of ROH length, except for FROH > 8Mb (− 0.03). Overall, inbreeding coefficients were not high for the genotyped animals. Autozygosity islands were evident across the genome (n = 62) and their genomic location did not largely differ within lineages. Enriched terms (p < 0.01) associated with defense response to bacteria (GO:0042742), immune complex reaction (GO:0045647), pr... Mostrar Tudo |
Palavras-Chave: |
Padroes ROH. |
Thesagro: |
Endogamia; Gado Nelore; Genética Animal; Genoma. |
Thesaurus Nal: |
Homozygosity. |
Categoria do assunto: |
G Melhoramento Genético |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/188276/1/12864-2018-Article-5060-APAGAR.pdf
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Marc: |
LEADER 03204naa a2200397 a 4500 001 2101339 005 2018-12-12 008 2018 bl uuuu u00u1 u #d 024 7 $ahttps://dx.doi.org/10.1186%2Fs12864-018-5060-8$2DOI 100 1 $aPERIPOLLI, E. 245 $aAutozygosity islands and ROH patterns in Nellore lineages$bevidence of selection for functionally important traits.$h[electronic resource] 260 $c2018 520 $aAbstract Background The aim of this study was to assess genome-wide autozygosity in a Nellore cattle population and to characterize ROH patterns and autozygosity islands that may have occurred due to selection within its lineages. It attempts also to compare estimates of inbreeding calculated from ROH (FROH), genomic relationship matrix (FGRM), and pedigree-based coefficient (FPED). Results The average number of ROH per animal was 55.15 ± 13.01 with an average size of 3.24 Mb. The Nellore genome is composed mostly by a high number of shorter segments accounting for 78% of all ROH, although the proportion of the genome covered by them was relatively small. The genome autozygosity proportion indicates moderate to high inbreeding levels for classical standards, with an average value of 7.15% (178.70 Mb). The average of FPED and FROH, and their correlations (− 0.05 to 0.26) were low. Estimates of correlation between FGRM-FPED was zero, while the correlation (− 0.01 to − 0.07) between FGRM-FROH decreased as a function of ROH length, except for FROH > 8Mb (− 0.03). Overall, inbreeding coefficients were not high for the genotyped animals. Autozygosity islands were evident across the genome (n = 62) and their genomic location did not largely differ within lineages. Enriched terms (p < 0.01) associated with defense response to bacteria (GO:0042742), immune complex reaction (GO:0045647), pregnancy-associated glycoproteins genes (GO:0030163), and organism growth (GO:0040014) were described within the autozygotic islands. Conclusions Low FPED-FROH correlation estimates indicate that FPED is not the most suitable method for capturing ancient inbreeding when the pedigree does not extend back many generations and FROH should be used instead. Enriched terms (p < 0.01) suggest a strong selection for immune response. Non-overlapping islands within the lineages greatly explain the mechanism underlying selection for functionally important traits in Nellore cattle. 650 $aHomozygosity 650 $aEndogamia 650 $aGado Nelore 650 $aGenética Animal 650 $aGenoma 653 $aPadroes ROH 700 1 $aMETZGER, J. 700 1 $aLEMOS, M. V. A. de 700 1 $aSTAFUZZA, N. B. 700 1 $aKLUSKA, S. 700 1 $aOLIVIERI, B. F. 700 1 $aFEITOSA, F. L. B. 700 1 $aBERTON, M. P. 700 1 $aLOPES, F. B. 700 1 $aMUNARI, D. P. 700 1 $aLOBO, R. B. 700 1 $aMAGNABOSCO, C. de U. 700 1 $aDI CROCE, F. 700 1 $aOSTERSTOCK, J. 700 1 $aDENISE, S. 700 1 $aPEREIRA, A. S. C. 700 1 $aBALDI, F. 773 $tBMC Genomics$gv. 19, 680, 2018.
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Registro original: |
Embrapa Cerrados (CPAC) |
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Biblioteca(s): |
Embrapa Florestas; Embrapa Pecuária Sul. |
Data corrente: |
05/12/2016 |
Data da última atualização: |
05/12/2016 |
Tipo da produção científica: |
Artigo em Anais de Congresso |
Autoria: |
ABREU, U. G. P. de; DIAS, F. R. T.; BARIONI, L. G.; FASIABEN, M. do C. R.; LAMPERT, V. do N.; COSTA, F. P.; MOREIRA, J. M. M. A. P.; GOMES, E. G. |
Afiliação: |
URBANO GOMES PINTO DE ABREU, CPAP; FERNANDO RODRIGUES TEIXEIRA DIAS, CPAP; LUIS GUSTAVO BARIONI, CNPTIA; MARIA DO CARMO RAMOS FASIABEN, CNPTIA; VINICIUS DO NASCIMENTO LAMPERT, CPPSUL; FERNANDO PAIM COSTA, CNPGC; JOSE MAURO M AVILA PAZ MOREIRA, CNPF; ELIANE GONCALVES GOMES, SGI. |
Título: |
Greenhouse gas emissions intensity assessment in beef cattle production systems: a data envelopment analysis (DEA) approach with variable returns to scale. |
Ano de publicação: |
2016 |
Fonte/Imprenta: |
In: INTERNATIONAL SYMPOSIUM ON GREENHOUSE GASES IN AGRICULTURE, 2., 2016, Campo Grande, MS. Proceedings... Brasília, DF: Embrapa, 2016. |
Páginas: |
p. 195-199. |
Série: |
(Embrapa Gado de Corte. Documentos, 216). |
Idioma: |
Inglês |
Notas: |
Coordenador: Roberto Giolo de Almeida. II SIGEE. |
Conteúdo: |
This paper aims at evaluating the efficiency of beef cattle productive systems in the Cerrado, Pampa and Pantanal biomes, regarding their emissions intensity (CO2 equivalent per kilogram of carcass weight produced). |
Palavras-Chave: |
Gases do efeito estufa. |
Thesagro: |
Efeito estufa; Gado de corte. |
Thesaurus NAL: |
Beef cattle; Greenhouse gas emissions. |
Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/150884/1/abreu-greenhouse.pdf
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Marc: |
LEADER 01309naa a2200301 a 4500 001 2057914 005 2016-12-05 008 2016 bl --- 0-- u #d 100 1 $aABREU, U. G. P. de 245 $aGreenhouse gas emissions intensity assessment in beef cattle production systems$ba data envelopment analysis (DEA) approach with variable returns to scale.$h[electronic resource] 260 $c2016 300 $ap. 195-199. 490 $a(Embrapa Gado de Corte. Documentos, 216). 500 $aCoordenador: Roberto Giolo de Almeida. II SIGEE. 520 $aThis paper aims at evaluating the efficiency of beef cattle productive systems in the Cerrado, Pampa and Pantanal biomes, regarding their emissions intensity (CO2 equivalent per kilogram of carcass weight produced). 650 $aBeef cattle 650 $aGreenhouse gas emissions 650 $aEfeito estufa 650 $aGado de corte 653 $aGases do efeito estufa 700 1 $aDIAS, F. R. T. 700 1 $aBARIONI, L. G. 700 1 $aFASIABEN, M. do C. R. 700 1 $aLAMPERT, V. do N. 700 1 $aCOSTA, F. P. 700 1 $aMOREIRA, J. M. M. A. P. 700 1 $aGOMES, E. G. 773 $tIn: INTERNATIONAL SYMPOSIUM ON GREENHOUSE GASES IN AGRICULTURE, 2., 2016, Campo Grande, MS. Proceedings... Brasília, DF: Embrapa, 2016.
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Embrapa Pecuária Sul (CPPSUL) |
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