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Registro Completo |
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Biblioteca(s): |
Embrapa Agricultura Digital; Embrapa Pecuária Sul. |
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Data corrente: |
02/01/2014 |
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Data da última atualização: |
22/01/2020 |
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Tipo da produção científica: |
Resumo em Anais de Congresso |
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Autoria: |
GIACHETTO, P. F.; PEREIRA, F. C. P.; MOKRY, F. B.; HIGA, R. H.; MUDADU, M. A.; SILVA, M. V.; NICIURA, S. C. M.; CARDOSO, F. F.; ALENCAR, M. M.; MEIRELLES, S. L. C.; LIMA, A. O.; REGITANO, L. C. A. |
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Afiliação: |
POLIANA FERNANDA GIACHETTO, CNPTIA; FERNANDA C. P. PEREIRA; FABIANA B. MOKRY; ROBERTO HIROSHI HIGA, CNPTIA; MAURICIO DE ALVARENGA MUDADU, CPPSE; MARCOS VINICIUS GUALBERTO B SILVA, CNPGL; SIMONE CRISTINA MEO NICIURA, CPPSE; FERNANDO FLORES CARDOSO, CPPSUL; MAURICIO MELLO DE ALENCAR, CPPSE; SARAH L. C. MEIRELLES, UFV; ANDRESSA O. LIMA, UFSCar; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE. |
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Título: |
Initial analysis of copy number variations in canchim beef cattle with extreme phenotypes for ribeye area. |
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Ano de publicação: |
2013 |
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Fonte/Imprenta: |
In: INTERNATIONAL PLANT & ANIMAL GENOME, 21., 2013, San Diego. [Abstracts...]. [S.l.: s.n.], 2013. |
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Páginas: |
Não paginado. |
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Idioma: |
Inglês |
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Notas: |
Pôster P0572. |
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Conteúdo: |
Genomic structural variation, in the form of large-scale insertions and deletions, as well as inversions and translocations, are referred to as copy number variations (CNVs). Compared to single nucleotide polymorphisms (SNPs), CNVs have potentially greater effects on gene structure, dosage and regulation, being an important source of phenotypic variation. In humans, CNVs are widespread in the genome and have been shown to be associated with complex traits. In livestock species, the characterization of this genetic variation is an important step toward linking genes or genomic regions with phenotypic traits of economic importance. Studies in cattle have revealed some CNVs associated with differences in host parasite resistance and breed-specific differences in adaptation, health, and production traits. We report initial data from an analysis of CNVs in Canchim, a synthetic cattle (5/8 Charolais + 3/8 Zebu) that has been selected for meat production in Brazil. Using the PennCNV software and data from 192 Canchim DNA samples with extreme phenotypes for ribeye area, genotyped with Illumina BovineHD BeadChip, a total of 6,985 CNVs were detected. The regions ranged from 20,012bp to 4,157,122bp, with mean and median of 140,484bp and 81,303bp, respectively. Copy number gains (62.09%) were found to be more common than deletions. Gene content of discovered CNVs and functional enrichment analysis are being assessed using Ensembl genes and cattle RefSeq databases, and PANTHER classification system, respectively. We expect to use these findings in genome wide association studies to better understand the genetic variation underlying meat quality in beef cattle. MenosGenomic structural variation, in the form of large-scale insertions and deletions, as well as inversions and translocations, are referred to as copy number variations (CNVs). Compared to single nucleotide polymorphisms (SNPs), CNVs have potentially greater effects on gene structure, dosage and regulation, being an important source of phenotypic variation. In humans, CNVs are widespread in the genome and have been shown to be associated with complex traits. In livestock species, the characterization of this genetic variation is an important step toward linking genes or genomic regions with phenotypic traits of economic importance. Studies in cattle have revealed some CNVs associated with differences in host parasite resistance and breed-specific differences in adaptation, health, and production traits. We report initial data from an analysis of CNVs in Canchim, a synthetic cattle (5/8 Charolais + 3/8 Zebu) that has been selected for meat production in Brazil. Using the PennCNV software and data from 192 Canchim DNA samples with extreme phenotypes for ribeye area, genotyped with Illumina BovineHD BeadChip, a total of 6,985 CNVs were detected. The regions ranged from 20,012bp to 4,157,122bp, with mean and median of 140,484bp and 81,303bp, respectively. Copy number gains (62.09%) were found to be more common than deletions. Gene content of discovered CNVs and functional enrichment analysis are being assessed using Ensembl genes and cattle RefSeq databases, and PANTHER classifica... Mostrar Tudo |
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Palavras-Chave: |
Bioinformática; Copy number variations; Polimorfismo de nucleotídeo único; Single nucleotide polymorphisms. |
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Thesagro: |
Variação Genética. |
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Thesaurus Nal: |
Bioinformatics; Genetic variation; Single nucleotide polymorphism. |
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Categoria do assunto: |
X Pesquisa, Tecnologia e Engenharia |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/94588/1/P0572.odt
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/97848/1/P0572.odt
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Marc: |
LEADER 02834nam a2200361 a 4500
001 1974748
005 2020-01-22
008 2013 bl uuuu u00u1 u #d
100 1 $aGIACHETTO, P. F.
245 $aInitial analysis of copy number variations in canchim beef cattle with extreme phenotypes for ribeye area.$h[electronic resource]
260 $aIn: INTERNATIONAL PLANT & ANIMAL GENOME, 21., 2013, San Diego. [Abstracts...]. [S.l.: s.n.]$c2013
300 $aNão paginado.
500 $aPôster P0572.
520 $aGenomic structural variation, in the form of large-scale insertions and deletions, as well as inversions and translocations, are referred to as copy number variations (CNVs). Compared to single nucleotide polymorphisms (SNPs), CNVs have potentially greater effects on gene structure, dosage and regulation, being an important source of phenotypic variation. In humans, CNVs are widespread in the genome and have been shown to be associated with complex traits. In livestock species, the characterization of this genetic variation is an important step toward linking genes or genomic regions with phenotypic traits of economic importance. Studies in cattle have revealed some CNVs associated with differences in host parasite resistance and breed-specific differences in adaptation, health, and production traits. We report initial data from an analysis of CNVs in Canchim, a synthetic cattle (5/8 Charolais + 3/8 Zebu) that has been selected for meat production in Brazil. Using the PennCNV software and data from 192 Canchim DNA samples with extreme phenotypes for ribeye area, genotyped with Illumina BovineHD BeadChip, a total of 6,985 CNVs were detected. The regions ranged from 20,012bp to 4,157,122bp, with mean and median of 140,484bp and 81,303bp, respectively. Copy number gains (62.09%) were found to be more common than deletions. Gene content of discovered CNVs and functional enrichment analysis are being assessed using Ensembl genes and cattle RefSeq databases, and PANTHER classification system, respectively. We expect to use these findings in genome wide association studies to better understand the genetic variation underlying meat quality in beef cattle.
650 $aBioinformatics
650 $aGenetic variation
650 $aSingle nucleotide polymorphism
650 $aVariação Genética
653 $aBioinformática
653 $aCopy number variations
653 $aPolimorfismo de nucleotídeo único
653 $aSingle nucleotide polymorphisms
700 1 $aPEREIRA, F. C. P.
700 1 $aMOKRY, F. B.
700 1 $aHIGA, R. H.
700 1 $aMUDADU, M. A.
700 1 $aSILVA, M. V.
700 1 $aNICIURA, S. C. M.
700 1 $aCARDOSO, F. F.
700 1 $aALENCAR, M. M.
700 1 $aMEIRELLES, S. L. C.
700 1 $aLIMA, A. O.
700 1 $aREGITANO, L. C. A.
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Esconder MarcMostrar Marc Completo |
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Registro original: |
Embrapa Agricultura Digital (CNPTIA) |
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Biblioteca |
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Origem |
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Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
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Registro Completo
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Biblioteca(s): |
Embrapa Suínos e Aves. |
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Data corrente: |
17/11/2020 |
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Data da última atualização: |
17/11/2020 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
B - 1 |
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Autoria: |
BESSA, M. J.; HAAS, S.; RAMOS, S. C.; ROCHA, R.; RECH, D. V.; REBELATTO, R.; DUARTE, S. C.; COLDEBELLA, A.; VAZ, C. S. L. |
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Afiliação: |
MARJO CARDÓ BESSA, UFRGS; SIMONE HAAS, SES/RS; ROSANE CAMPANHER RAMOS, SES/RS; RAQUEL ROCHA, SES/RS; DAIANE VOSS RECH, CNPSA; RAQUEL REBELATTO, CNPSA; SABRINA CASTILHO DUARTE, CNPSA; ARLEI COLDEBELLA, CNPSA; CLARISSA SILVEIRA LUIZ VAZ, CNPSA. |
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Título: |
Survey of campylobacter in foods implicated in foodborne diseases in Southern Brazil. |
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Ano de publicação: |
2020 |
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Fonte/Imprenta: |
Revista do Instituto de Medicina Tropical de São Paulo, v. 62, artigo e90, 2020. |
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DOI: |
http://doi.org/10.1590/S1678-9946202062090 |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: Campylobacter is not routinely tested in foodborne disease investigations in Brazil. Here, we studied the occurrence of Campylobacter among other food-related bacteria commonly found in foodborne disease outbreaks reported in Rio Grande do Sul State, Southern Brazil. Seventy-two food samples were analyzed by using culture-based detection methods during the 18-month investigation of 36 foodborne disease outbreaks. The sampled foods from the foodborne disease outbreaks were all negative for Campylobacter. However, at least one of other routinely investigated foodborne-related bacteria was detected in 29.17% (21/72) of the samples. Taken together, these results suggest the need to monitor Campylobacter in foodborne diseases to detect sporadic cases caused by Campylobacter that might go unnoticed in Rio Grande do Sul. |
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Palavras-Chave: |
Surto. |
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Thesagro: |
Campilobacteriose; Segurança Alimentar. |
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Thesaurus NAL: |
Campylobacter; Food safety; Outbreak investigation. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/217902/1/final9338.pdf
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Marc: |
LEADER 01730naa a2200301 a 4500
001 2126712
005 2020-11-17
008 2020 bl uuuu u00u1 u #d
024 7 $ahttp://doi.org/10.1590/S1678-9946202062090$2DOI
100 1 $aBESSA, M. J.
245 $aSurvey of campylobacter in foods implicated in foodborne diseases in Southern Brazil.$h[electronic resource]
260 $c2020
520 $aAbstract: Campylobacter is not routinely tested in foodborne disease investigations in Brazil. Here, we studied the occurrence of Campylobacter among other food-related bacteria commonly found in foodborne disease outbreaks reported in Rio Grande do Sul State, Southern Brazil. Seventy-two food samples were analyzed by using culture-based detection methods during the 18-month investigation of 36 foodborne disease outbreaks. The sampled foods from the foodborne disease outbreaks were all negative for Campylobacter. However, at least one of other routinely investigated foodborne-related bacteria was detected in 29.17% (21/72) of the samples. Taken together, these results suggest the need to monitor Campylobacter in foodborne diseases to detect sporadic cases caused by Campylobacter that might go unnoticed in Rio Grande do Sul.
650 $aCampylobacter
650 $aFood safety
650 $aOutbreak investigation
650 $aCampilobacteriose
650 $aSegurança Alimentar
653 $aSurto
700 1 $aHAAS, S.
700 1 $aRAMOS, S. C.
700 1 $aROCHA, R.
700 1 $aRECH, D. V.
700 1 $aREBELATTO, R.
700 1 $aDUARTE, S. C.
700 1 $aCOLDEBELLA, A.
700 1 $aVAZ, C. S. L.
773 $tRevista do Instituto de Medicina Tropical de São Paulo$gv. 62, artigo e90, 2020.
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Registro original: |
Embrapa Suínos e Aves (CNPSA) |
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