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 | Acesso ao texto completo restrito à biblioteca da Embrapa Pecuária Sudeste. Para informações adicionais entre em contato com cppse.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Pecuária Sudeste. |
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Data corrente: |
28/08/2018 |
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Data da última atualização: |
03/01/2019 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
LOPES, P. D.; OKINO, C. H.; FERNANDO, F. S.; PAVANI, C.; CASAGRANDE, V. M.; LOPEZ, R. F. V.; MONTASSIER, M. F. de; MONTASSIER, H. J. |
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Afiliação: |
Priscila Diniz Lopes, UNESP; CINTIA HIROMI OKINO, CPPSE; Filipe Santos Fernando, UNESP; Caren Pavani, UNESP; Viviane Mariguela Casagrande, UNESP; Renata F. V. Lopez, USP; Maria de Fátima Silva Montassier, UNESP; Helio José Montassier, UNESP. |
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Título: |
Inactivated infectious bronchitis virus vaccine encapsulated in chitosan nanoparticles induces mucosal immune responses and effective protection against challenge. |
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Ano de publicação: |
2018 |
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Fonte/Imprenta: |
Vaccine, v. 36, p. 2630-2636, abr. 2018. |
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Volume: |
36 |
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Idioma: |
Inglês |
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Conteúdo: |
Avian infectious bronchitis virus (IBV) is one of the most important viral diseases of poultry. The mucosa of upper respiratory tract, specially the trachea, is the primary replication site for this virus. However, conventional inactivate IBV vaccines usually elicit reduced mucosal immune responses and local protection. Thus, an inactivated IBV vaccine containing BR-I genotype strain encapsulated in chitosan nanoparticles (IBV-CS) was produced by ionic gelation method to be administered by oculo-nasal route to chickens. IBV-CS vaccine administered alone resulted in markedly mucosal immune responses, characterized by high levels of anti-IBV IgA isotype antibodies and IFNc gene expression at 1dpi. The association of live attenuated Massachusetts IBV and IBV-CS vaccine also induced strong mucosal immune responses, though a switch from IgA isotype to IgG was observed, and IFNc gene expression peak was late (at 5 dpi). Efficacy of IBV-CS was evaluated by tracheal ciliostasis analysis, histopathology examination, and viral load determination in the trachea and kidney. The results indicated that IBV-CS vaccine administered alone or associated with a live attenuated heterologous vaccine induced both humoral and cellmediated immune responses at the primary site of viral replication, and provided an effective protection against IBV infection at local (trachea) and systemic (kidney) sites. |
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Thesagro: |
Bronquite; Vacina; Vacina Inativada. |
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Thesaurus Nal: |
Inactivated vaccines; Infectious bronchitis; Infectious bronchitis virus; Mucosal immunity. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02347naa a2200313 a 4500
001 2094598
005 2019-01-03
008 2018 bl uuuu u00u1 u #d
100 1 $aLOPES, P. D.
245 $aInactivated infectious bronchitis virus vaccine encapsulated in chitosan nanoparticles induces mucosal immune responses and effective protection against challenge.$h[electronic resource]
260 $c2018
300 $a36
490 $v36
520 $aAvian infectious bronchitis virus (IBV) is one of the most important viral diseases of poultry. The mucosa of upper respiratory tract, specially the trachea, is the primary replication site for this virus. However, conventional inactivate IBV vaccines usually elicit reduced mucosal immune responses and local protection. Thus, an inactivated IBV vaccine containing BR-I genotype strain encapsulated in chitosan nanoparticles (IBV-CS) was produced by ionic gelation method to be administered by oculo-nasal route to chickens. IBV-CS vaccine administered alone resulted in markedly mucosal immune responses, characterized by high levels of anti-IBV IgA isotype antibodies and IFNc gene expression at 1dpi. The association of live attenuated Massachusetts IBV and IBV-CS vaccine also induced strong mucosal immune responses, though a switch from IgA isotype to IgG was observed, and IFNc gene expression peak was late (at 5 dpi). Efficacy of IBV-CS was evaluated by tracheal ciliostasis analysis, histopathology examination, and viral load determination in the trachea and kidney. The results indicated that IBV-CS vaccine administered alone or associated with a live attenuated heterologous vaccine induced both humoral and cellmediated immune responses at the primary site of viral replication, and provided an effective protection against IBV infection at local (trachea) and systemic (kidney) sites.
650 $aInactivated vaccines
650 $aInfectious bronchitis
650 $aInfectious bronchitis virus
650 $aMucosal immunity
650 $aBronquite
650 $aVacina
650 $aVacina Inativada
700 1 $aOKINO, C. H.
700 1 $aFERNANDO, F. S.
700 1 $aPAVANI, C.
700 1 $aCASAGRANDE, V. M.
700 1 $aLOPEZ, R. F. V.
700 1 $aMONTASSIER, M. F. de
700 1 $aMONTASSIER, H. J.
773 $tVaccine$gv. 36, p. 2630-2636, abr. 2018.
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Embrapa Pecuária Sudeste (CPPSE) |
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| Registros recuperados : 25 | |
| 3. |  | MONTASSIER, M. F. S.; BRENTANO, L.; RICHTZENHAIN, L. J.; OKINO, C. H.; MONTASSIER, H. J. Genetic diversity of partial S1 an N gene sequences of infectious bronckitis virus isolates from Brazil. Virus Reviews and Research, v. 15, supl. 1, p. 196, oct. 2010. Trabalho apresentado no NATIONAL MEETING OF VIROLOGY, 21.; MERCOSUL MEETING OF VIROLOGY, 5. Projeto/Plano de Ação: 03.09.01900-01.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Suínos e Aves. |
|   |
| 4. | | MONTASSIER, M. F. S.; BRENTANO, L.; RICHTZENHAIN, L. J.; MONTASSIER, H. J. Diversity in relevant epitopes of S1 glycoprotein and nucleocapsid (N) protein of Brazilian variants of infectious bronchitis virus. Virus Reviews and Research, v. 15, supl. 1, p. 196, oct. 2010. Trabalho apresentado no NATIONAL MEETING OF VIROLOGY, 21.; MERCOSUL MEETING OF VIROLOGY, 5. Projeto/Plano de Ação: 03.09.01900-01.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Suínos e Aves. |
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| 6. | | OKINO, C. H.; MONTASSIER, M. de F. S.; SILVA, K. R.; FERNANDO, F. S.; BRENTANO, L.; MONTASSIER, H. J. Avian infectious bronchitis vírus (IBV): effect of vaccine doses on mucosal imune responses and protection after challenge in chickens. In: WORLD´S POULTRY CONGRESS, 24., 2012, Salvador. Abstract... Salvador: WSPA, 2012. 1 CD-ROM. World's Poultry Science Journal, v. 68, supl. 1, 2012. Projeto/Plano de Ação: 05.11.11.002.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Suínos e Aves. |
|  |
| 7. | | SANTOS, I. L.; OKINO, C. H.; MONTASSIER, M. de F. S.; SILVA, K. R.; FERNANDO, F. S.; MONTASSIER, H. J. Immune-protection mechanisms against late challenge with avian infectious bronchitis vírus (IBV) induced by a single-dose of an attenuated vaccine in day-old chicks. In: WORLD´S POULTRY CONGRESS, 24., 2012, Salvador. Abstract... Salvador: WSPA, 2012. 1 CD-ROM. World's Poultry Science Journal, v. 68, supl. 1, 2012. Projeto/Plano de Ação: 05.11.11.002| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Suínos e Aves. |
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| 8. | | SANTOS, I. L.; GIBERTONI, A. M.; MONTASSIER, M. de F. S.; OKINO, C. H.; MONTASSIER, H. J. Improvement of immunodiagnosis of avian infectious bronchitis virus (IBV) infection by the detection of IgM and IgG antibodies using a new recombinant nucleoprotein-based Elisa. In: WORLD´S POULTRY CONGRESS, 24., 2012, Salvador. Abstract... Salvador: WSPA, 2012. 1 CD-ROM. World's Poultry Science Journal, v. 68, supl. 1, 2012. Projeto/Plano de Ação: 05.11.11.002.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Suínos e Aves. |
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| 11. | | MATTOS, G. L. M.; OKINO, C. H.; TREVISOL, I. M.; MORES, M. A. Z.; LOPES, L. dos S.; MONTASSIER, H. J. Avaliação da imunidade celular contra isolado de campo de vírus da bronquite infecciosa (VBI) das galinhas. In: ANAIS DA CONFERÊNCIA NACIONAL DE DEFESA AGROPECUÁRIA: Defesa agropecuária a serviço de um estado de excelência, 5, 2014, Florianópolis, SC. Anais... Concórdia: Embrapa Suínos e Aves, 2014. 1 CD-ROM. ISBN 978-85-68630-00-6. P. 353| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Suínos e Aves. |
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| 12. | | BORZI, M. M.; MONTASSIER, M. F. S.; OLIVEIRA, E. S.; SILVA, K. R.; SILVA, F. S.; OKINO, C. H.; MONTASSIER, H. J.; REISCHAK, D.; MENDONÇA, A. de O. Cloned nucleoprotein (NP) gene of avian influenza virus for using as a positive control in syber green I real time RT-PCR (RRT-PCR). In: BRAZILIAN CONGRESS OF VIROLOGY, 23.; MERCOSUR MEETING OF VIROLOGY, 7., 2012, Foz do Iguaçu. Virus and Research? Foz do Iguaçu: SBV, 2012. p. 409. Journal of the Brazilian Society for Virology, v. 17, n. 2, suppl. 1, 2012. Projeto/Plano de Ação: 11.11.11.111.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Suínos e Aves. |
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| 13. | | OKINO, C. H.; MALAGO JUNIOR, W.; MARCONDES, C. R.; GIGLIOTI, R.; MONTASSIER, H. J.; OLIVEIRA, H. N. DE; OLIVEIRA, M. C. de S. CD4 bovine gene: differential polymorphisms among cattle breeds and a new tool for rapid identification. Veterinary Immunology and Immunopathology, v. 251, sep. 2022, 110462. 18 p.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 14. | | FERNANDO, F. S.; OKINO, C. H.; SILVA, K. R.; FERNANDES, C. C.; GONÇALVES, M. C. M.; MONTASSIER, M. F. S.; VASCONCELOS, R. O.; MONTASSIER, H. J. Increased expression of Interleukin-6 related to nephritis in chickens challenged with an Avian infectious bronchitis virus variant. Pesquisa Veterinária Brasileira, Brasília, DF, v. 35, n. 3, p. 216-222, mar. 2015.| Biblioteca(s): Embrapa Unidades Centrais. |
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| 15. | | OKINO, C. H.; ALESSI, A. C.; MONTASSIER, M. de F. S.; ROSA, A. J. de M.; WANG, X.; MONTASSIER, H. J. Humoral and Cell-Mediated Immune Responses to Different Doses of Attenuated Vaccine Against Avian Infectious Bronchitis Virus. Viral Immunology, Nova York, v. 26, n. 4, p. 1-9, 2013.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 1 |
| Biblioteca(s): Embrapa Cerrados. |
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| 16. | | LOPES, P. D.; OKINO, C. H.; FERNANDO, F. S.; PAVANI, C.; CASAGRANDE, V. M.; LOPEZ, R. F. V.; MONTASSIER, M. F. de; MONTASSIER, H. J. Inactivated infectious bronchitis virus vaccine encapsulated in chitosan nanoparticles induces mucosal immune responses and effective protection against challenge. Vaccine, v. 36, p. 2630-2636, abr. 2018. 36| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 17. | | OKINO, C. H.; MORES, M. A. Z.; MATTOS, G. L. M.; ESTEVES, P. A.; BRENTANO, L.; MONTASSIER, H. J.; TREVISOL, I. M. Diferentes respostas imunes locais induzidas após desafio com isolados de campo brasileiros do vírus da bronquite infecciosa das galinhas. In: CONFERÊNCIA FACTA, 2014, Atibaia. [Anais...] Campinas: Fundação APINCO de Ciência e Tecnologia Avícolas, 2014. 1 CD-ROM.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Suínos e Aves. |
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| 18. | | BORZI, M. M.; PIZA, V. T.; MONTASSIER, M. F. S.; MORA, A. G.; OKINO, C. H.; REISCHAK, D.; MENDONÇA, A.; MONTASSIER, H. J. Development of a microplate immunocapture (IC) RT-PCR assays for the detection of avian influenza virus (AIV) and infectious bronchitis virus (IBV). In: BRAZILIAN CONGRESS OF VIROLOGY, 23.; MERCOSUR MEETING OF VIROLOGY, 7., 2012, Foz do Iguaçu. Virus and Research? Foz do Iguaçu: SBV, 2012. p.468-469. Journal of the Brazilian Society for Virology, v. 17, n. 2, suppl. 1, 2012. Projeto/Plano de Ação: 11.11.11.111.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Suínos e Aves. |
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| 19. | | LOPES, P. D.; OKINO, C. H.; FERNANDO, F. S.; PAVANI, C.; MARIGUELA, V. C.; MONTASSIER, M. DE F. S.; MONTASSIER, H. J. Comparative evaluation of immune responses and protection of chitosan nanoparticles and oil-emulsion adjuvants in avian coronavirus inactivated vaccines in chickens. Vaccines, v.9, n.12, 1457, 2021.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 20. | | MORES, M. A. Z.; OKINO, C. H.; MONTASSIER, H. J.; MATTOS, G. L. M.; BRENTANO, L.; COLDEBELLA, A.; ESTEVES, P. A.; TREVISOL, I. M. Microscopic lesions after challenge with two Brazilian avian infectious bronchitis variants. Journal of the Brazilian Society for Virology, Ribeirão Preto, v. 19, 2014. Suppl. 2. Edição dos anais do 25º. Brazilian Congress of Virology e 9º. Mercosur Meeting of Virology, Ribeirão Preto, set./out, 2014. p. 231| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Suínos e Aves. |
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| Registros recuperados : 25 | |
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| Nenhum registro encontrado para a expressão de busca informada. |
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